Results 21 to 30 of about 34,497 (254)
Frontiers in Pharmacology, 2023 Renal sodium retention is an essential indicator that is used for the prognosis of cirrhosis with ascites that requires diuretic treatment to restore sodium homeostasis.
Tun-Pin Hsueh +5 more
doaj +1 more source
Influence of Spironolactone on Matrix Metalloproteinase-2 in Acute Decompensated Heart Failure
Arquivos Brasileiros de Cardiologia, 2015 Background: Matrix metalloproteinases (MMPs) are a family of enzymes important for the resorption of extracellular matrices, control of vascular remodeling and repair.
João Pedro Ferreira +5 more
doaj +1 more source
Efficacy and Safety of Spironolactone in the Treatment of Resistant Hypertension：a Meta-analysis [PDF]
Zhongguo quanke yixue, 2022 BackgroundAs a special type of hypertension, resistant hypertension has complex etiology, is difficult to treat, and more likely to lead to target organ damage.
ZHANG Ping, ZOU Jing, GAO Cunzhou, WU Aiping, LI Rongshan
doaj +1 more source
Unexpected Antiviral Activity of Spironolactone
, 2020 Epstein-Barr virus (EBV) is a human herpesvirus associated with clinical infections and several types of malignancies. Sankar Swaminathan, MD, and colleagues showed that a hypertension/heart failure drug, spironolactone, also has anti-EBV effects.
Swaminathan, S.; Verma, D.
core +1 more source
International Journal of Women's Dermatology, 2019 Purpose: The necessity of serum potassium monitoring for healthy women who are prescribed spironolactone for acne has been debated. The aim of this study was to compare the incidence of hyperkalemia in women 18 to 45 years of age to that in women 46 to ...
Rebecca M. Thiede +6 more
doaj +1 more source
, 2020 This is a study of the effects of mineralocorticoid receptor blocker Spironolactone on cardiovasular function in persons with End-Stage Renal disease on hemodialysis treatment.
Michael Eklund +2 more
core +1 more source
SPIRONOLACTONE IN FIRST-LINE ANTIHYPERTENSIVE THERAPY: EFFECT ON VASCULAR REMODELING [PDF]
, 2023 Introduction. Previously, clinical studies have proven a pronounced antihypertensive effect of spironolactone in patients with true resistant hypertension.
Anna Mikhailovna Torunova
core +1 more source
Spironolactone in dermatology:uses in acne and beyond
, 2020 Spironolactone is a synthetic aldosterone receptor antagonist, with a role off-label in various dermatological conditions. Its antiandrogenic properties make it suitable for diseases in which excess androgen production results in unwanted and ...
Searle, T. N. +2 more
core +1 more source
Outcomes of Spironolactone Withdrawal in Dilated Cardiomyopathy With Improved Ejection Fraction
Frontiers in Cardiovascular Medicine, 2021 Background: The feasibility of spironolactone withdrawal in dilated cardiomyopathy patients with improved ejection fraction remains unknown. This study sought to determine whether spironolactone can be withdrawn safely in this circumstance.Methods ...
Yanjia Chen +10 more
doaj +1 more source
, 2006 BACKGROUND: The beneficial effects of beta-blockers and aldosterone receptor antagonists are now well established in patients with severe systolic chronic heart failure (CHF).
Rouleau, Jean-Lucien +18 more
core +2 more sources