Altered gut microbiota-host bile acid metabolism in IBS-D patients with liver depression and spleen deficiency pattern. [PDF]
Background Dysregulation of gut microbiota–host bile acid (BA) co-metabolism is a critical pathogenic factor of diarrhea-predominant irritable bowel syndrome (IBS-D). Traditional Chinese Medicine (TCM), instructed by pattern differentiation, is effective
Du L +9 more
europepmc +2 more sources
The Role of Ganyu in Formation of Liver Depression and Spleen Deficiency Syndrome: Analysis From Gut Microbiota. [PDF]
Conclusion: Oral administration of senna combined with restraint stress had different effects on visceral hypersensitivity, gut microbiota composition, and metabolic pathways in rats with D-IBS liver depression and spleen deficiency syndrome, and the ...
Wang Y +8 more
europepmc +2 more sources
Vitamin D and endothelial function in chronic kidney disease [PDF]
PhDVitamin D deficiency in patients with chronic kidney disease, measured by reduced serum concentrations of 25 hydroxy vitamin D, is highly prevalent and associated with both endothelial dysfunction and an increased risk of cardiovascular disease ...
Dreyer, Gavin
core +4 more sources
Role of the spleen in Plasmodium vivax: a reticulocyte-prone non-lethal malaria [PDF]
“Plasmodium vivax” és el paràsit causant de malària humana amb més àmplia distribució i és responsable cada any de 100-300 milions de casos clinics, incloent algunes manifestacions severes i mort. P.
Ferrer Almirall, Mireia
core +7 more sources
The serotonin receptor 3E variant is a risk factor for female IBS-D [PDF]
Irritable bowel syndrome (IBS) is a gut-brain disorder of multifactorial origin. Evidence of disturbed serotonergic function in IBS accumulated for the 5-HT3 receptor family.
Herzog, Wolfgang +73 more
core +1 more source
Impact of Vitamin D Supplementation on Arterial Vasomotion, Stiffness and Endothelial Biomarkers in Chronic Kidney Disease Patients [PDF]
Background: Cardiovascular events are frequent and vascular endothelial function is abnormal in patients with chronic kidney disease (CKD). We demonstrated endothelial dysfunction with vitamin D deficiency in CKD patients; however the impact of ...
Chitalia, N +31 more
core +1 more source
Spleen findings in drowning [PDF]
A retrospective study of spleen findings in 42 victims of drowning and a comparison group of 42 cases of asphyxiation due to other causes (hanging, ligature strangulation and manual strangulation), that were matched for sex, age, body weight and build ...
M. Graw +5 more
core +1 more source
Noradrenergic and Cholinergic Reinnervation of Islet Grafts in Diabetic Rats [PDF]
Grafted islets become denervated due to the islet transplantation procedure. The aim of the present study was 1) to examine whether islet grafts in the liver, the spleen, and under the kidney capsule in rats become reinnervated following the ...
Oestreicher, AB +27 more
core +1 more source
Gut Microbiota Dysbiosis: Pathogenesis, Diseases, Prevention, and Therapy. [PDF]
ABSTRACT Dysbiosis refers to the disruption of the gut microbiota balance and is the pathological basis of various diseases. The main pathogenic mechanisms include impaired intestinal mucosal barrier function, inflammation activation, immune dysregulation, and metabolic abnormalities.
Shen Y +5 more
europepmc +2 more sources

