Results 41 to 50 of about 757,464 (353)

Dynamic Development of Fecal Microbiome During the Progression of Diabetes Mellitus in Zucker Diabetic Fatty Rats

Frontiers in Microbiology, 2019
Background: Although substantial efforts have been made to link the gut microbiota to type 2 diabetes, dynamic changes in the fecal microbiome under the pathological conditions of diabetes have not been investigated.Methods: Four male Zucker diabetic ...
Wen Zhou, Huiying Xu, Libin Zhan, Xiaoguang Lu, Lijing Zhang   +4 more
doaj   +1 more source

Trauma of the Spleen

, 2000
Potentially serious abdominal injury is encountered on an almost daily basis in major emergency departments. Approximately 10% of the thousands of yearly fatalities are considered the direct result of abdominal injury, and survivor morbidity is significantly influenced by abdominal trauma (Budnick and Chaiken 1985).
Corthouts, B., Degryse, Hendrik R.
openaire   +5 more sources

Abscess of the spleen

Srpski arhiv za celokupno lekarstvo, 2005
Splenic abscess is a rare disease but with increasing frequency. The authors present 9 patients with splenic abscess treated at the Institute of Digestive System Diseases, Clinical Centre of Serbia, in a period from January 1, 1986 to May 15, 2004. Splenic abscess was the complication of septic endocarditis in 4, trauma in 2, dental infection in 1 ...
Radoje Colovic, Nikica Grubor, Vladimir Radak, Natasa Colovic   +3 more
openaire   +4 more sources

Pogostemon cablin Acts as a Key Regulator of NF-κB Signaling and Has a Potent Therapeutic Effect on Intestinal Mucosal Inflammation

Mediators of Inflammation
Persistent intestinal inflammation is a major contributor to various diseases, including digestive disorders, immune dysregulation, and cancer. The NF-κB signaling pathway is pivotal in the inflammatory response of intestinal cells, regulating the ...
Yuqing Deng, Xin Liang, Long Zhao, Xin Zhou, Jianqin Liu, Zhi Li, Shanshan Chen, Guohui Xiao   +7 more
doaj   +1 more source

Gut Microbial Dysbiosis and Changes in Fecal Metabolic Phenotype in Precancerous Lesions of Gastric Cancer Induced With N-Methyl-N′-Nitro-N-Nitrosoguanidine, Sodium Salicylate, Ranitidine, and Irregular Diet

Frontiers in Physiology, 2021
Background and Aims: Precancerous lesions of gastric cancer (PLGC) are the most important pathological phase with increased risk of gastric cancer (GC) and encompass the key stage in which the occurrence of GC can be prevented.
Fuhao Chu, Fuhao Chu, Fuhao Chu, Yicong Li, Xiangmei Meng, Xiangmei Meng, Yuan Li, Yuan Li, Tao Li, Tao Li, Mengyin Zhai, Mengyin Zhai, Haocheng Zheng, Haocheng Zheng, Tianxi Xin, Tianxi Xin, Zeqi Su, Zeqi Su, Jie Lin, Jie Lin, Ping Zhang, Xia Ding, Xia Ding   +22 more
doaj   +1 more source

Radiation-related lymphopenia is associated with spleen irradiation dose during radiotherapy in patients with hepatocellular carcinoma

Radiation Oncology, 2017
BackgroundThe decrease in peripheral blood lymphocytes induced by radiation lessens the antitumour effect of the immune response, which might cause immunosuppression.
Jing Liu, Qianqian Zhao, Weiye Deng, Jie Lu, Xiao-qing Xu, Ren-ben Wang, Xia Li, J. Yue   +7 more
semanticscholar   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Dendritic cells derived exosomes migration to spleen and induction of inflammation are regulated by CCR7

Scientific Reports, 2017
Mature dendritic cells (DCs) home to secondary lymphoid organs through CC chemokine receptor 7 (CCR7). Exosomes derived from DCs (DC-exos) are reported to migrate to spleen and induce inflammation in vivo.
G. Wei, Yuan Jie, L. Haibo, Chaoneng Wu, Huang Dong, Jianbing Zhu, Junjie Guo, Leilei Ma, Hong-tao Shi, Yunzeng Zou, G. Junbo   +10 more
semanticscholar   +1 more source

Hemangioma of the spleen

Srpski arhiv za celokupno lekarstvo, 2006
Although the most frequent benign tumors of the spleen, hemangiomas are very rare, much rarer than hemangiomas of the liver. They manifest as localized (either single or multiple) or diffuse lesions, vary from solid to cystic, histologically from capillary to cavernous.
Vladimir Radak, Radoje Colovic, Natasa Colovic, Marijan Micev, Vesna Cemerikic-Martinovic   +4 more
openaire   +4 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source