Results 211 to 220 of about 58,017 (329)

The Immunological Consequences of Clonal Hematopoiesis in Heart Failure

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Inflammation is increasingly recognized as a central driver of heart failure (HF), particularly in older adults, yet the underlying immune mechanisms remain diverse and incompletely understood. Clonal hematopoiesis (CH), defined by the expansion of somatically mutated hematopoietic clones, has emerged as a risk factor for the development of ...
Megan A. Evans, Kenneth Walsh
wiley   +1 more source

Splicing and transcription touch base: co-transcriptional spliceosome assembly and function

Nature reviews. Molecular cell biology, 2017
Lydia Herzel, D. Ottoz, T. Alpert, K. Neugebauer   +3 more
semanticscholar   +1 more source

Controlled dynamic remodeling of the spliceosome active site enables the first step of splicing. [PDF]

Proc Natl Acad Sci U S A
Martino G, Manigrasso J, La Sala G, Marcia M, De Vivo M.   +4 more
europepmc   +1 more source

Life History and Smoltification Shape Genomic Signatures of Thermal Tolerance in Chinook Salmon

Molecular Ecology, Volume 35, Issue 1, January 2026.
ABSTRACT Temperature is a key determinant of survival and distribution in ectothermic species, but how variation in thermal resilience is influenced by developmental transitions, life‐history strategies, and their interaction with population‐specific genomic variation is poorly understood.
David C. H. Metzger, Timothy M. Healy, Kyle Wellband, Patricia M. Schulte   +3 more
wiley   +1 more source

A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation

Science, 2019
S. Fica, C. Oubridge, M. E. Wilkinson, A. Newman, K. Nagai   +4 more
semanticscholar   +1 more source

Control of 3' splice site selection in <i>S. cerevisiae</i> by a highly conserved amino acid within the Prp8 α-finger domain. [PDF]

RNA
Liu Y, Paulson JC, Hoskins AA.
europepmc   +1 more source

Differential Binding of Heterogeneous Nuclear Ribonucleoproteins to mRNA Precursors prior to Spliceosome Assembly In Vitro

, 1992
Maria Bennett, Serafı́n Piñol-Roma, David Staknis, Gideon Dreyfuss, Robin Reed   +4 more
openalex   +2 more sources

Translational control in plants: from basic mechanisms to environmental and developmental responses

The Plant Journal, Volume 125, Issue 1, January 2026.
SUMMARY Protein synthesis is an essential process for all living organisms and is tightly regulated to ensure the proper production of proteins needed for growth, development, and stress responses. As sessile organisms, plants have evolved distinct mechanisms to regulate translation, allowing them to adapt to their environment.
Jade Lyons, Catharina Merchante, Anna N. Stepanova, Jose M. Alonso   +3 more
wiley   +1 more source

The yeast U2A′/U2B″ complex is required for pre-spliceosome formation [PDF]

, 1998
Friederike Caspary, Bertrand Séraphin
openalex   +1 more source

CCDC97 is a Promising Predictor in Cancer Diagnosis: A Pan Cancer Analysis

Analytical Cellular Pathology, Volume 2026, Issue 1, 2026.
Background Coiled‐coil domain‐containing 97 (CCDC97) can bind to the splicing factor SF3B complex to participate significantly in pre‐mRNA splicing. However, there may be a risk of cancer development in the case of disrupted mechanism, necessitating further in‐depth investigation of the underlying mechanism.
Changye Yang, Ruirui Yang, Rundong Wang, Guo Ma, Lixin Hua, Maciej Wnuk   +5 more
wiley   +1 more source