Results 191 to 200 of about 483,589 (358)

Tensor decomposition of multi-dimensional splicing events across multiple tissues to identify splicing-mediated risk genes associated with complex traits. [PDF]

PLoS Comput Biol
Yan Y, Chen R, Kang H, Tan Y, Tiwari A, Ma S, Wen Z, Zhong X, Li B.   +8 more
europepmc   +1 more source

Alternative splicing generates variants in important functional domains of human slow skeletal troponin T.

, 1987
Reinhold Gahlmann, Anthony B. Troutt, Robert Wade, Peter W. Gunning, Larry Kedes   +4 more
openalex   +1 more source

Chronic Psychological Stress Induces Cardiomyocyte Hypertrophy Through Corticosterone‐Glucocorticoid Receptor‐LAMA5 Axis

Advanced Science, EarlyView.
In vivo experiments suggest that cardiomyocyte hypertrophy is an early manifestation of cardiac pathological changes induced by chronic psychological stress. In vivo and in vitro experiments suggest that the corticosterone‐glucocorticoid receptor‐LAMA5 axis mediates cardiomyocyte hypertrophy induced by chronic psychological stress. The clinical results
Chuanjing Zhang, Yongfei Song, Xiaojun Jin, Qingbo Xu, Honghua Ye, Zhuonan Wu, Hui Lin, Jiale Hu, Chen Huang, Jianqing Zhou, Jiangfang Lian   +10 more
wiley   +1 more source

ALDH18A1 has carcinogenic functions and regulates alternative splicing events of DNA repair-related genes in esophageal carcinoma cells. [PDF]

Sci Rep
Yongkang W, Yisireyili M, Abudureyimu K, Enomoto A.   +3 more
europepmc   +1 more source

Patterns of fibronectin gene expression and splicing during cell migration in chicken embryos [PDF]

, 1988
Charles ffrench‐Constant, Richard O. Hynes   +1 more
openalex   +1 more source

H3K36me3‐Guided m6A Modification of Oncogenic L1CAM‐AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma

Advanced Science, EarlyView.
L1CAM‐AS1 is identified as a novel H3K36me3‐guided, m6A‐modified long noncoding RNA (lncRNA) in hepatocellular carcinoma (HCC) cells. L1CAM‐AS1 stabilizes RAN protein, enhances M2 macrophages‐released CCL5‐induced nuclear import of RELA, activates the NF‐κB signaling, up‐regulates CCL2 expression and secretion from HCC cells, and enhances M2 ...
Teng Wang, Linyu Han, Yanfei Huo, Long Zhang, Yizhou Huang, Nasha Zhang, Ming Yang   +6 more
wiley   +1 more source

Splicing-dependent restriction of the HBZ gene by Tax underlies biphasic HTLV-1 infection. [PDF]

PLoS Pathog
Liang Y, Lyu C, Xu S, Tan C, Jiang Q, Liu B, Yang S, Huang W, Zhou R, Yuan X, Zuo X, Matsuoka M, Ma G.   +12 more
europepmc   +1 more source

Construction of a yeast strain devoid of mitochondrial introns and its use to screen nuclear genes involved in mitochondrial splicing. [PDF]

, 1987
Bertrand Séraphin, Aren Boulet, M. Simon, G. Faye   +3 more
openalex   +1 more source

Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA

Advanced Science, EarlyView.
Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin, Runyu Cao, Xuemei Bai, Jiahua Yuan, Wanwei Sun, Yi Zheng, Xiaopeng Qi, Wei Zhao, Bingyu Liu, Chengjiang Gao   +9 more
wiley   +1 more source

Minigenes enhance heterologous expression and prevent aberrant splicing of mouse Spink1. [PDF]

Sci Rep
Berke G, Sahin-Tóth M.
europepmc   +1 more source