Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Efektivitas Tanaman Naungan Dan Pupuk Bioprotektan Kompos Trichoderma SP. Untuk Mengendalikan Penyakit Busuk Umbi Pada Tanaman Bawang Merah [PDF]
Onion (Allium ascallonicum L.) is one of horticultural commodities that has high economic value and national priority to cultivate. The purpose of this study was to determine the effectiveness of shade plant and bioprotectant fertilizer (compost ...
Indiani, N. K. (Ni) +2 more
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Validation and sensitivity analysis of InfoCrop simulation model for growth and yield of Indian mustard varieties at Allahabad [PDF]
Field experiment was carried out at SHUATS, Allahabad, to study validation and sensitivity analysis of InfoCrop model with the data sets generated respectively during Rabi season of 2016-17. The main plot treatments and sub-plot treatment consisted three
Graham, A. (Anosh) +2 more
core
EFFECTS OF ROW SPACING AND SEEDING RATES ON SOME AGRONOMICAL TRAITS OF SPRING CANOLA (BRASSICA NAPUS L.) CULTIVARS [PDF]
The objective of the study was to evaluate the effects of row spacing and seeding rates on agronomical traits of three spring canola (Brassica napus L.) cultivars in Iran during 2003-2004. Traits evaluated were plant height, number of seeds pod-1, number
Yazdifar SHAHIN, Ramea VALIOLLAH
doaj
The Waterlogging Tolerance of Wheat Varieties in Western of Turkey
This research was conducted to determine the wheat varieties against waterlogging which was clearly increased in recent years. For this purpose, this study was performed at Field Crops and Soil Science Department of Agricultural Faculty of Adnan Menderes
Ilkay Yavas, Aydin Unay, Mehmet Aydin
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Puccinia horiana P. Henn. is the pathogen which caused of white rust on chrysanthemum. It is the most serious disease on chrysanthemum. Study on the effect of varieties, defoliation, and fungicide application against rust diseases (Puccinia horiana) was ...
E Silvia Yusuf, - Suhardi
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

