Results 71 to 80 of about 3,491 (191)
Under iron‐limited conditions, FsrA base‐pairs with the intergenic region between epeX and epeE, enhancing epeE translation and triggering EPE production. Toxin‐mediated cell lysis releases nutrients, including iron, which can be taken up by surviving cells.
Sarah Miercke +3 more
wiley +1 more source
The role of Spo0A in regulation of Ssp4 production.
(A) Total DNA isolated from SM101, spo0A null mutant IH101, and the complementing strain IH101(pMRS123), or plasmid pMRS123 alone, was subjected to PCR analysis using spo0A-specific internal primers CPP68 and CPP69 [17].
Bruce A. McClane (45208) +3 more
core +1 more source
Under-detection of endospore-forming Firmicutes in metagenomic data
Microbial diversity studies based on metagenomic sequencing have greatly enhanced our knowledge of the microbial world. However, one caveat is the fact that not all microorganisms are equally well detected, questioning the universality of this approach ...
Sevasti Filippidou +6 more
doaj +1 more source
Background Bacillus cereus 0–9, a Gram-positive, endospore-forming bacterium isolated from healthy wheat roots in our previous research, is considered to be an effective biocontrol strain against several soil-borne plant diseases. SpoVG, a regulator that
Qiubin Huang +6 more
doaj +1 more source
CodY is a global regulator whose phosphorylation at serine 215 by PrkC/YbdM alters its DNA binding, thereby modulating gene expression and impacting motility, biofilm formation, cytotoxicity, and pathogenicity in Bacillus cereus, suggesting a conserved regulatory mechanism in Firmicutes ABSTRACT CodY acts as a key regulatory protein involved in ...
Mounia Kortebi +7 more
wiley +1 more source
High- and Low-Threshold Genes in the Spo0A Regulon of Bacillus subtilis [PDF]
ABSTRACT The master regulator for entry into sporulation in Bacillus subtilis is the response regulator Spo0A, which directly governs the expression of about 121 genes. Using cells in which the synthesis of Spo0A was under the control of an inducible promoter or in which ...
Masaya, Fujita +2 more
openaire +2 more sources
Chemical and Stress Resistances of Clostridium difficile Spores and Vegetative Cells
Clostridium difficile is a Gram-positive, sporogenic and anaerobic bacterium that causes a potentially fatal colitis. C. difficile enters the body as dormant spores that germinate in the colon to form vegetative cells that secrete toxins and cause the ...
Adrianne N Edwards +5 more
doaj +1 more source
This study demonstrates that the production of surfactin by B. subtilis R31 needs to be balanced. Excessive surfactin will weaken the colonisation ability and disease control effect of the strain. By targeting the regulation of the surfactin signalling pathway, synthetic microbial communities can be designed for sustainable disease control.
Hao‐Jun Chen +10 more
wiley +1 more source
The formation and visualisation of three day old biofilms in the spo0A mutant.
The biofilms produced attached to a TC flask were compared for R20291, R20291_spo0A::CT and R20291_spo0A::CT::pspo0A. These attached biofilms were matured over a three day period, before they were detached from the plastic by agitation for visualisation ...
Esmeralda Valiente (114199) +4 more
core +1 more source
Impact of deoxycholate on Clostridioides difficile growth, toxin production, and sporulation
Purpose: Bile acids play an important role in Clostridioides difficile life cycle. Deoxycholate (DCA), one of the most abundant secondary bile acids, is known to inhibit vegetative growth and toxin production.
Yukino Usui +6 more
doaj +1 more source

