Results 41 to 50 of about 11,396 (179)

The Molecular Pathology of Prion Diseases [PDF]

, 2004
Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of invariably fatal neurodegenerative disorders. Uniquely, they may present as sporadic, inherited, or infectious forms, all of which involve conversion of the normal ...
Herms, Jochen, Kretzschmar, Hans A., Vassallo, Neville   +2 more
core  

Transmission of scrapie prions to primate after an extended silent incubation period [PDF]

, 2015
Citation: Comoy, E. E., Mikol, J., Luccantoni-Freire, S., Correia, E., Lescoutra-Etchegaray, N., Durand, V., . . . Deslys, J. P. (2015). Transmission of scrapie prions to primate after an extended silent incubation period. Scientific Reports, 5.
Andreoletti, O., Baron, T., Benestad, S. L., Brown, P., Casalone, C., Comoy, E. E., Correia, E., Dehen, C., Deslys, J. P., Durand, V., Greenlee, J. J., Lescoutra-Etchegaray, N., Luccantoni-Freire, S., Mikol, J., Richt, Juergen A.   +14 more
core   +3 more sources

Evidence for different seeding activities of misfolded tau in classical and rapidly progressive Alzheimer's disease

Brain Pathology, EarlyView.
The study analyzed the seeding activity of misfolded tau protein in Alzheimer's disease and rapidly progressive Alzheimer's disease patients and provides evidence for the existence of different tau assemblies supported by differences in cellular toxicity and morphology of thioflavin T‐positive real‐time quaking‐induced conversion products.
Matthias Schmitz, Katrin Thüne, Anna‐Lisa Fischer, Peter Hermann, Maria Cramm, Leonie Sheila Kadel, Wiebke Möbius, Jakob Matschke, Tayyaba Saleem, Neelam Younas, Saima Zafar, Hermann Altmeppen, Markus Glatzel, Inga Zerr   +13 more
wiley   +1 more source

Parkinsonism Associated with Pathological 123I-FP-CIT SPECT (DaTSCAN) Results as the Initial Manifestation of Sporadic Creutzfeldt-Jakob Disease

Case Reports in Neurological Medicine, 2018
Sporadic Creutzfeldt-Jakob disease (sCJD) is a type of progressive, subacute encephalopathy associated with spongiform degeneration of the central nervous system.
Sira Carrasco García de León, Juan Pablo Cabello, Ramón Ortiz, Julia Vaamonde   +3 more
doaj   +1 more source

A case of sporadic Creutzfeldt-Jakob disease [PDF]

Romanian Journal of Neurology, 2012
Sporadic Creutzfeldt-Jakob disease (CJD) is a very rare and fatal disease caused by prions – proteins with unique characteristics and infective potential.
Raoul Pop, Arta Teodorescu, Maria Tanasie, Ruxandra Joikits, Roxana Gheoca, Mihaela Simu   +5 more
doaj   +1 more source

Creutzfeldt-Jakob disease and homocysteine levels in plasma and cerebrospinal fluid [PDF]

, 2005
Background: There is evidence that homocysteine contributes to various neurodegenerative disorders. Objective: To assess the values of homocysteine in patients with Creutzfeldt-Jakob disease (CJD) in both cerebrospinal fluid (CSF) and plasma.
Bottiglieri T, Halliwell B, Hans A. Kretzschmar, Inga Zerr, Jens Wiltfang, Markus Otto, Otto M, Stefan Bleich, Stefan Kropp, Ubbink JB, Zerr I, Zerr I   +11 more
core   +1 more source

Probable sporadic Creutzfeldt–Jakob disease mimicking focal epilepsy

Epilepsy and Behavior Case Reports, 2019
Creutzfeldt–Jakob disease (CJD) presents with seizures as an early symptom in only approximately 3% of cases. These seizures often present as nonconvulsive status epilepticus (NCSE) or epilepsia partialis continua (EPC).
Pei-Shan Hsiao, Yuan-Ming Lee, Fu-Sin Chu, Chao-Lin Lee, Fang-Chun Liu, Ping-Huang Tsai   +5 more
doaj   +1 more source

Real time quaking-induced conversion analysis of cerebrospinal fluid in sporadic Creutzfeldt-Jakob disease [PDF]

, 2012
OBJECTIVE: Current cerebrospinal fluid (CSF) tests for sporadic Creutzfeldt-Jakob disease (sCJD) are based on the detection of surrogate markers of neuronal damage such as CSF 14-3-3 which are not specific for sCJD.
Andrews, Mary, Appleford, Nigel E, Caughey, Byron, Green, Alison J E, Head, Mark W, Knight, Richard S G, Mallinson, Gary, McGuire, Lynne I, Orrú, Christina D, Peden, Alexander H, Wilham, Jason M, Will, Robert G   +11 more
core   +1 more source

ENFERMEDAD DE JAKOB-CREUTZFELDT. A PROPÓSITO DE UN CASO

Revistas Argentina de Medicina, 2017
La enfermedad de Jakob-Creutzfeuldt esporádica es la más común de las patologías priónicas humanas. Se presenta el caso de una paciente de 59 años de edad internada por trastornos conductuales cognitivos, acompañados de mioclonías y mutismo acinético.
Lucía González, José Fernández, Vanesa Aguilar, Silvana Tobares, Melisa Contreras, Livio Lanciani, Jimena Boccardo, Juan Carlos Giugni   +7 more
doaj   +2 more sources

Determination of neuronal antibodies in suspected and definite Creutzfeldt-Jakob disease [PDF]

, 2018
IMPORTANCE Creutzfeldt-Jakob disease (CJD) and autoimmune encephalitis with antibodies against neuronal surface antigens (NSA-abs) may present with similar clinical features. Establishing the correct diagnosis has practical implications in the management
Bernabé, Reyes, Dalmau Obrador, Josep, Grau-Rivera, Oriol, Graus Ribas, Francesc, Molinuevo, José Luis, Munteis, Elvira, Pujadas, Francesc, Saiz Hinajeros, Albert, Salvador, Antoni, Saura, Júlia, Sánchez del Valle Díaz, Raquel, Titulaer, Maarten J., Ugarte, Antonio   +12 more
core   +1 more source