Results 111 to 120 of about 11,518 (218)

Fatal familial insomnia that begins with unconsciousness: A case report

Sleep Research, Volume 3, Issue 1, Page 71-77, March 2026.
Wenyan Liu, Xinyue Xing, Xiaoming Wang, Xuqian Liu, Mingyue Liu, Wei Shang, Zhaohong Xie   +6 more
wiley   +1 more source

Amyloid‐β Seeds in Alzheimer's Disease: Research Challenges and Implications

Journal of Neurochemistry, Volume 169, Issue 11, November 2025.
The amyloid cascade hypothesis places amyloid‐β (Aβ) at the center of Alzheimer's disease (AD) pathogenesis. Evidence suggests that AD progresses in two phases: an early phase driven by Aβ aggregation and a later phase that progresses at least partly independently of Aβ.
Natalie Beschorner, Ying Xu, Mathias Jucker, Alejandro Ruiz‐Riquelme   +3 more
wiley   +1 more source

The new variant of the Creutzfeldt-Jakob disease accounts for no relative increase of the Creutzfeldt-Jakob disease mortality rate in the United Kingdom; this fits ill with the new variant being the consequence of consumption of food infected with the agent of Bovine Spongiform Encephalopathy

BMC Public Health, 2003
Background A new variant of Creutzfeldt-Jakob disease was described in the United Kingdom. It is often claimed that it is caused by consumption of food infected with the agent of bovine spongiform encephalopathy.
Hénaut Alain, Laprevotte Ivan
doaj   +1 more source

Determination of neuronal antibodies in suspected and definite Creutzfeldt-Jakob disease [PDF]

, 2018
IMPORTANCE Creutzfeldt-Jakob disease (CJD) and autoimmune encephalitis with antibodies against neuronal surface antigens (NSA-abs) may present with similar clinical features. Establishing the correct diagnosis has practical implications in the management
Bernabé, Reyes, Dalmau Obrador, Josep, Grau-Rivera, Oriol, Graus Ribas, Francesc, Molinuevo, José Luis, Munteis, Elvira, Pujadas, Francesc, Saiz Hinajeros, Albert, Salvador, Antoni, Saura, Júlia, Sánchez del Valle Díaz, Raquel, Titulaer, Maarten J., Ugarte, Antonio   +12 more
core   +1 more source

MRI lesion profiles in sporadic Creutzfeldt–Jakob disease

Neurology, 2009
With respect to sporadic Creutzfeldt-Jakob disease (sCJD), six molecular subtypes (MM1, MM2, MV1, MV2, VV1, and VV2) have been described, which vary with respect to age at disease onset, disease duration, early symptoms, and neuropathology. MRI signal alterations were reported to correlate with distinct Creutzfeldt-Jakob disease (CJD) subtypes.
Meissner, B., Kallenberg, K., Sanchez-Juan, P., Collie, D., Summers, D. M., Almonti, S., Collins, S. J., Smith, P., Cras, P., Jansen, G. H., Brandel, J. P., Coulthart, M. B., Roberts, H., van Everbroeck, B., Galanaud, Damien, Mellina, V., Will, R. G., Zerr, I.   +17 more
openaire   +5 more sources

Prion disease: experimental models and reality [PDF]

, 2017
The understanding of the pathogenesis and mechanisms of diseases requires a multidisciplinary approach, involving clinical observation, correlation to pathological processes, and modelling of disease mechanisms.
Brandner, S, Jaunmuktane, Z
core   +1 more source

Pathological spectrum of sporadic Creutzfeldt–Jakob disease

Pathology
Human prion diseases are a rare group of transmissible neurodegenerative conditions which are classified according to their aetiology as sporadic, genetic or acquired forms. Creutzfeldt-Jakob disease (CJD) is the most common form of human prion disease, with the sporadic form accounting for ∼85% of all reported cases.
Diane L, Ritchie, Colin, Smith
openaire   +2 more sources

Prion disease diagnosis using subject-specific imaging biomarkers within a multi-kernel Gaussian process

NeuroImage: Clinical, 2019
Prion diseases are a group of rare neurodegenerative conditions characterised by a high rate of progression and highly heterogeneous phenotypes. Whilst the most common form of prion disease occurs sporadically (sporadic Creutzfeldt–Jakob disease, sCJD ...
Liane S. Canas, Carole H. Sudre, Enrico De Vita, Akin Nihat, Tze How Mok, Catherine F. Slattery, Ross W. Paterson, Alexander J.M. Foulkes, Harpreet Hyare, M. Jorge Cardoso, John Thornton, Jonathan M. Schott, Frederik Barkhof, John Collinge, Sébastien Ourselin, Simon Mead, Marc Modat   +16 more
doaj   +1 more source

Determinants of diagnostic investigation sensitivities across the clinical spectrum of sporadic Creutzfeldt-Jakob disease [PDF]

, 2017
To validate the provisional findings of a number of smaller studies and explore additional determinants of characteristic diagnostic investigation results across the entire clinical spectrum of sporadic Creutzfeldt-Jakob disease (CJD), an international ...
Almonti, S., Alpérovitch, A., Brandel, J.-P, Budka, H., Collins, S. J., Cuadrado-Corrales, N., de Pedro-Cuesta, J., Gelpi, E., Glatzel, M., Heinemann, U., Hewer, E., Jansen, G. H., Klug, G. M., Kretszchmar, H. A., Mackenzie, J., Masters, C. L., Mitrova, E., Murray, K., Olsen, E., Pocchiari, M., Poleggi, A., Sanchez-Juan, P., Tolnay, M., van Duijn, C., Will, R. G., Zerr, I.   +25 more
core  

Sporadic Creutzfeldt-Jakob disease

Neurology, 2004
To assess if clinical features, prion protein codon 129, and molecular subtype correlate with MRI basal ganglia hyperintensity in sporadic Creutzfeldt-Jakob disease (CJD).The authors studied 219 patients including 153 confirmed CJD cases for their neurologic symptoms and MRI findings.
Meissner, Bettina, Kohler, K., Kortner, K., Bartl, Mario, Jastrow, U., Mollenhauer, Brit, Schroter, A., Finkenstaedt, M., Windl, Otto, Poser, Sigrid, Kretzschmar, Hans A., Zerr, I.   +11 more
openaire   +3 more sources