Results 91 to 100 of about 5,084,169 (167)
Dental treatment and risk of variant CJD - a case control study [PDF]
Objective: Knowledge of risk factors for variant CJD (vCJD) remains limited, but transmission of prion proteins via re-useable medical devices, including dental instruments, or enhanced susceptibility following trauma to the oral cavity is a concern ...
Everington, D. +11 more
core +1 more source
All clinically-relevant blood components transmit prion disease following a single blood transfusion: a sheep model of vCJD [PDF]
Variant CJD (vCJD) is an incurable, infectious human disease, likely arising from the consumption of BSE-contaminated meat products. Whilst the epidemic appears to be waning, there is much concern that vCJD infection may be perpetuated in humans by the ...
Smith, Antony +58 more
core +1 more source
Differentiation of Prions from L-type BSE versus Sporadic Creutzfeldt-Jakob Disease
We compared transmission characteristics for prions from L-type bovine spongiform encephalopathy and MM2-cortical sporadic Creutzfeldt-Jakob disease in the Syrian golden hamster and an ovine prion protein–transgenic mouse line and isolated distinct prion
Simon Nicot +5 more
doaj +1 more source
A novel protective prion protein variant that colocalizes with kuru exposure. [PDF]
BACKGROUND: Kuru is a devastating epidemic prion disease that affected a highly restricted geographic area of the Papua New Guinea highlands; at its peak, it predominantly affected adult women and children of both sexes.
Whittaker, John +26 more
core +1 more source
A patient with a heterozygous variant of Creutzfeldt-Jakob disease (CJD) with a methionine/valine genotype at codon 129 of the prion protein gene was recently reported.
Daisy Bougard +8 more
doaj +1 more source
Sleep-wake disturbances in sporadic Creutzfeldt-Jakob disease.
BACKGROUND: The prevalence and characteristics of sleep-wake disturbances in sporadic Creutzfeldt-Jakob disease (sCJD) are poorly understood. METHODS: Seven consecutive patients with definite sCJD underwent a systematic assessment of sleep-wake ...
Achermann, P +21 more
core +1 more source
Creutzfeldt-Jakob disease (CJD) can be iatrogenically transmitted during transplants, grafts and transfusions from CJD infected donors and also contaminated surgical instruments.
Secker, Thomas
core +1 more source
Autoantibodies in sporadic Creutzfeldt-Jakob disease.
IMPORTANCE: The diagnosis of autoimmune and neurodegenerative conditions can be unclear. Treatments such as removing the associated tumor, if present, and immunosuppression can halt or often reverse the progression of autoimmune conditions, but there is ...
Angus-Leppan, H +4 more
core +1 more source

