Results 101 to 110 of about 18,335 (219)

A rapid and scalable density gradient purification method for Plasmodium sporozoites

Malaria Journal, 2012
Background Malaria remains a major human health problem, with no licensed vaccine currently available. Malaria infections initiate when infectious Plasmodium sporozoites are transmitted by Anopheline mosquitoes during their blood meal.
Kennedy Mark, Fishbaugher Matthew E, Vaughan Ashley M, Patrapuvich Rapatbhorn, Boonhok Rachasak, Yimamnuaychok Narathatai, Rezakhani Nastaran, Metzger Peter, Ponpuak Marisa, Sattabongkot Jetsumon, Kappe Stefan H, Hume Jen CC, Lindner Scott E   +12 more
doaj   +1 more source

APL1C antibody labelling of P. berghei sporozoites is specific to the APL1C protein.

A. Sporozoites perfused from control dsGFP-treated mosquitoes are labelled by APL1C protein. The top panel depicts merged images of representative sporozoites (scale bar 10 μm), whereas the images below show 3 channels of enlarged projections of ...
Corinne Genève (8423229), Christian Mitri (106839), Emma Brito-Fravallo (106850), Manuela Camille Aguirre-Botero (17965826), Kenneth D. Vernick (8423238), Eduardo Aliprandini (662949), Catherine Lavazec (106835), Natalia Marta Zmarlak (8423220)   +7 more
core   +1 more source

Translational Control of UIS4 Protein of the Host-Parasite Interface Is Mediated by the RNA Binding Protein Puf2 in Plasmodium berghei Sporozoites. [PDF]

, 2016
UIS4 is a key protein component of the host-parasite interface in the liver stage of the rodent malaria parasite Plasmodium berghei and required for parasite survival after invasion.
Jorge M Santos, Silva, Patrícia A. G. C., Guerreiro, Ana, Mair, Gunnar, Gunnar R Mair, Janse, C.J., Joanna A M Braks, Ana Guerreiro, Santos, J.M., Braks, Joanna A. M., Chris J Janse, Guerreiro, A., Mair, G.R., Santos, Jorge M., Silva, P.A.G.C., Janse, Chris J., Braks, J.A.M., Patrícia A G C Silva, Silva Patrícia A. G. C., Guerreiro Ana, Santos Jorge M., Janse Chris J., Mair Gunnar R., Braks Joanna A. M.   +23 more
core   +1 more source

An Improved Theileria parva Sporozoite Seroneutralization Assay for the Identification of East Coast Fever Immune Correlates

Antibodies
Background: Immune correlates of protection are ideal tools to predict treatment or vaccine efficacy. However, the accuracy of the immune correlate and the capability to robustly predict the outcome of a vaccine candidate are determined by the ...
Hannah Chege, Samuel Githigia, James Gathumbi, Naomi Chege, Rose Ojuok, Josiah Odaba, Stephen Mwalimu, Harriet Oboge, Lucilla Steinaa, Vishvanath Nene, Anna Lacasta   +10 more
doaj   +1 more source

Efficient development of plasmodium liver stage-specific memory CD8+ T cells during the course of blood-stage malarial infection.

, 2007
Immunity to Plasmodium liver stages in individuals in malaria-endemic areas is inextricably linked to concomitant blood-stage parasitemia. Although Plasmodium sporozoite infection induces measurable CD8+ T cell responses, the development of memory T ...
Dabeiba Bernal‐Rubio, Rai, Urvashi, Julius C. R. Hafalla, Fidel Zavala, Hafalla, Julius CR, Rodriguez, Ana, Ana Rodriguez, Zavala, Fidel, Urvashi Rai, Bernal-Rubio, Dabeiba   +9 more
core   +1 more source

Gliding Motility and Traversal Capacity of Wt and Δp52 sporozoites.

, 2013
(A) Representative immunofluorescence staining with anti-PfCSP antibodies of the trails produced by Wt and mutant sporozoites deficient in P52 expression (Δp52-1 and Δp52-2) as well as Wt sporozoites, treated with cytochalasin D, an inhibitor of ...
Audrey Gego (353873), Olivier Silvie (44628), Shahid M. Khan (190458), Stephen L. Hoffman (239213), Chris J. Janse (12383), Marga van de Vegte-Bolmer (359384), Samir Yalaoui (44627), Andrew P. Waters (15293), Jean-Francois Franetich (5653960), Dominique Mazier (44632), Robert W. Sauerwein (82233), Geert-Jan van Gemert (250563), Ben C. L. van Schaijk (236288), Melissa R. van Dijk (250560)   +13 more
core   +1 more source

Development of a sporozoite malaria vaccine [PDF]

Memórias do Instituto Oswaldo Cruz, 1986
Nussenzweig, Victor, Nussenzweig, Ruth S.   +1 more
openaire   +4 more sources

The isolation of viable coccidial sporozoites

Parasitology, 1964
A method is described by which viable sporozoites of the sheep parasite,Eimeria arloingi, may be obtained in sterile solution and free of any extraneous vegetable matter. Faeces are washed through metal sieves and the oocysts separated by a gravity floatation technique.
openaire   +2 more sources

Genetically attenuated P36p-deficient Plasmodium berghei sporozoites confer long-lasting and partial cross-species protection.

, 2007
Contains fulltext : 51720.pdf (Publisher’s version ) (Closed access)Immunisation with live, radiation-attenuated sporozoites (RAS) or genetically attenuated sporozoites (GAS) of rodent plasmodial parasites protects against subsequent ...
Franetich, J.F., Douradinha, B.G., Dijk, M.R. van, Mota, Maria M., Ataide, Ricardo, Franetich, Jean-Francois, Thompson, Joanne, Thompson, J., Mota, M.M., Janse, C.J., Luty, A.J.F., Sauerwein, R.W., Mazier, Dominique, Gemert, G.J.A. van, Waters, A.P., van Dijk, Melissa R., Waters, Andrew P., Luty, Adrian J. F., Mazier, D., Janse, Chris J., Douradinha, Bruno, Ataide, R., Sauerwein, Robert, van Gemert, Geert-Jan   +23 more
core   +1 more source

Transmission indices of malaria in Anopheles mosquitoes in an agrarian community adjourning Osogbo, Southwestern Nigeria

Journal of Vector Borne Diseases
Background & objectives: Mosquitoes transmit malaria and other infectious diseases. A thorough understanding of the dynamics, biting behavior, and infectiousness of Anopheles vector sporozoites is required to calculate transmission indices and develop ...
Zarat O Iwalewa, Olabanji A Surakat, Mohammed A Rufai, Kamilu A Fasasi, Harun K Aremu, Monsuru A Adeleke   +5 more
doaj   +1 more source