Results 81 to 90 of about 14,501 (156)
Immunoepidemiological studies typically reveal slow, age-dependent acquisition of immune responses against Plasmodium falciparum sporozoites. Naturally acquired immunity against preerythrocytic stages is considered inadequate to confer protection against
Vittoria Offeddu +7 more
doaj +1 more source
Plasmodium sporozoite motility: an update
Plasmodium, the causative agent of malaria, employs its own actin/myosin-based motor for forward locomotion, penetration of molecular and cellular barriers, and invasion of target cells. The sporozoite is unique amongst the extracellular Plasmodium developmental forms in that it has to cross considerable distances and different tissues inside the ...
Montagna, Georgina Nuri +2 more
openaire +5 more sources
Preservation of Coccidial Sporozoites by Freezing [PDF]
MAINTENANCE of cultures of coccidia for experimental purposes is laborious and expensive. To overcome these difficulties, we attempted to freeze and store sporozoites of Eimeria meleagrimitis Tyzzer, 1929, and E. tenella (Railliet and Lucet, 1891) Fantham, 1909, in liquid nitrogen vapour.
D J, Doran, J M, Vetterling
openaire +2 more sources
Imaging malaria parasites across scales and time
Abstract The idea that disease is caused at the cellular level is so fundamental to us that we might forget the critical role microscopy played in generating and developing this insight. Visually identifying diseased or infected cells lays the foundation for any effort to curb human pathology.
Julien Guizetti
wiley +1 more source
Shedding of host autophagic proteins from the parasitophorous vacuolar membrane of Plasmodium berghei [PDF]
The hepatic stage of the malaria parasite Plasmodium is accompanied by an autophagy-mediated host response directly targeting the parasitophorous vacuolar membrane (PVM) harbouring the parasite.
Agop-Nersesian, Carolina +5 more
core +2 more sources
Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz +4 more
wiley +1 more source
Maria M. Mota: Bringing Plasmodium Liver Infection to the Centre Stage of Malaria Research
Sílvia Portugal +2 more
doaj +1 more source
Traction force generation in Plasmodium sporozoites is modulated by a surface adhesin
Abstract Plasmodium sporozoites are the highly polarised and motile forms of the malaria parasite transmitted by mosquitoes to the vertebrate hosts. Sporozoites use myosin motors to generate retrograde flow of actin filaments. These are linked to plasma membrane spanning adhesins, which in turn bind to the extracellular environment, resulting in ...
Johanna Ripp +4 more
wiley +1 more source
Antibody-Mediated Protection against
Plasmodium sporozoites are injected into the skin as mosquitoes probe for blood. From here, they migrate through the dermis to find blood vessels which they enter in order to be rapidly carried to the liver, where they invade hepatocytes and develop into
Yevel Flores-Garcia +6 more
doaj +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source

