Results 91 to 100 of about 330,960 (360)

Memory deficits in Sprague Dawley rats with spontaneous ventriculomegaly

open access: yesBrain and Behavior, 2020
Introduction Spontaneous ventriculomegaly has been observed in rats that were presumed normal. Because the external phenotype of these animals is unremarkable, they can be inadvertently included in behavioral experiments, despite the considerable ...
Hiram Luna‐Munguia   +3 more
doaj   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

open access: yesAdvanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin   +18 more
wiley   +1 more source

Skeletal Muscle Fatigue in Slow and Fast Muscles of Type 2 Diabetic Sprague Dawley Rats

open access: yesJournal of Rawalpindi Medical College, 2017
Background: To evaluate the effects of type 2 diabetes mellitus on fatigability of soleus (slow) and extensor digitorium longus (EDL) (fast) muscles of female Sprague Dawley rats.
Mehvish Ashfaq
doaj  

Catabolism of chylomicron triacylglycerol and cholesteryl ester in genetically obese rats

open access: yesJournal of Lipid Research, 1977
The catabolism of chylomicrons was investigated in genetically obese rats and their nonobese littermates, and was compared with catabolism in older Sprague–Dawley rats with body weights similar to the obese rats and their younger controls.
T G Redgrave
doaj   +1 more source

Development of a Novel Synthetic Hydrogel Sealant for Effective Prevention of Liver Resection‐Associated Bile Leakage

open access: yesAdvanced Healthcare Materials, EarlyView.
A dual‐crosslinking poly(ethylene glycol) (PEG) hydrogel is presented that rapidly solidifies and progressively adheres to tissue, achieving durable sealing of bile leaks. In hepatectomy models, this system prevents postoperative complications more effectively than conventional sealants, highlighting its translational potential as a safe and efficient ...
Kazuyoshi Matsubara   +7 more
wiley   +1 more source

Female Sprague Dawley Rats Show Impaired Spatial Memory in the 8-Arm Radial Maze under Dim Blue and Red Light

open access: yesInternational Journal of Zoology, 2010
Light intensity and wavelength strongly influence mood and cognition in humans and rodent animal models. The aim of the present study was to explore if dim white (7.6–17.7 lux) , blue (1.3–2.3 lux), and red light (0.8–1.4 lux) affect spatial memory of ...
Michael Pirchl   +2 more
doaj   +1 more source

Intratubular Spermatocytic Seminomas in 2 Sprague-Dawley Rats

open access: yesJournal of Toxicologic Pathology, 2014
This report describes 2 cases of spontaneous intratubular spermatocytic seminomas in Sprague-Dawley rats. These rats were sacrificed at 10 weeks old (case 1) and 40 weeks old (case 2), respectively. Macroscopically, there were no remarkable changes in either case.
Ishigami, Noriaki, Shimouchi, Koji
openaire   +3 more sources

Histopathologic Changes in Liver and Kidney Tissues from Male Sprague Dawley Rats Treated with Rhaphidophora Decursiva (Roxb.) Schott Extract

open access: yes, 2014
Rhaphidophora decursiva (Roxb.) Schott is commonly used to treat colon cancer among Chinese community in Malaysia. This study aims to evaluate histopathologic changes in liver and kidney tissues after treated with R.
S. Arsad, N. Esa, H. Hamzah
semanticscholar   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

open access: yesAdvanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen   +9 more
wiley   +1 more source

Histology of the rectus abdominis muscle in rats subjected to cranial and caudal devascularization Histologia do músculo reto do abdome de ratos submetidos à desvascularização cranial e caudal

open access: yesActa Cirúrgica Brasileira, 2012
PURPOSE: To investigate the microscopic changes in the rectus abdominis muscle in rats subjected to five delay procedure. METHODS: 30 male holtzmann rats, weighting between 250 and 350 grams, were used. The animals were divided into five groups (n=6): A -
Walder Costa   +3 more
doaj   +1 more source

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