Results 111 to 120 of about 908,946 (295)

Heat‐Suppressing Projection Two‐Photon Lithography Enables High‐Throughput Sub‐Micrometer Manufacturing of Biopolymer Hydrogels for Tissue Engineering

Advanced Science, EarlyView.
The iLEAP technique integrates high‐throughput two‐photon lithography with extrusion printing, bridging sub‐micrometer precision and macroscopic scaffold fabrication. By employing a low‐exothermic photoinitiator, it mitigates thermal damage to biopolymers and preserves bioactivity.
Qifeng Guan, Yanzhe Fu, Xiangyu Xu, Naitao Li, Sen Hou, Kai Wang, Yufan Wang, Jiakun Li, Ping Li, Jiebo Li, Lizhen Wang, Yubo Fan   +11 more
wiley   +1 more source

Histology of the rectus abdominis muscle in rats subjected to cranial and caudal devascularization Histologia do músculo reto do abdome de ratos submetidos à desvascularização cranial e caudal

Acta Cirúrgica Brasileira, 2012
PURPOSE: To investigate the microscopic changes in the rectus abdominis muscle in rats subjected to five delay procedure. METHODS: 30 male holtzmann rats, weighting between 250 and 350 grams, were used. The animals were divided into five groups (n=6): A -
Walder Costa, Alcino Lázaro da Silva, Gustavo Rocha Costa, Tarcizo Afonso Nunes   +3 more
doaj   +1 more source

Ion‐Driven Regulation of Ca2+ Flow by Ti/Zn Composite Activates ERK/MAPK Signaling and Maintains Mitochondrial Homeostasis to Promote Macrophage‐Mediated Bone Regeneration

Advanced Science, EarlyView.
A 3D‐printed interpenetrating Ti/Zn composite enables sustained Zn2+ release to regulate intracellular Ca2+ redistribution, preserve mitochondrial homeostasis, activate ERK/MAPK signaling, and promote M2 macrophage polarization, thereby enhancing osteoimmune‐mediated bone regeneration and peri‐implant osseointegration.
Wanyi Huang, Qiyue Zhang, Yueyang Qiu, Haocheng Suo, Zengqian Liu, Bing Bai, Qiang Wang, Qing Zhou   +7 more
wiley   +1 more source

Spontaneous lactation in virgin Sprague-Dawley rats [PDF]

Laboratory Animals, 1971
Spontaneous milky secretion was found in 24 out of 46 virgin female Sprague-Dawley rats aged 1 year which had been given 30 mg of 9,10-dimethyl-1,2-benzanthracene (DMBA) when 50 days old. The secretory activity was associated with hyperplasia both of mammary epithelium and connective tissue.
openaire   +2 more sources

Engineering Morphological Anisotropy to Control the In Vivo Transport Dynamics, Clearance, and Biodistribution of Silica Nanocarriers

Advanced Science, EarlyView.
Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li, Yingjie Yu, Tianchang He, Xiaoyan Fang, Wenhua Yang, Luying Zhou, Hao Fan, Guimei Lin, Daniel Crespy, Katharina Landfester, Junfeng Zhang, Shuai Jiang   +11 more
wiley   +1 more source

Polysorbate 20 increases oral absorption of digoxin in wild-type Sprague Dawley rats, but not in mdr1a(-/-) Sprague Dawley rats

, 2016
The aim was to investigate the ability of polysorbate 20 to alter oral digoxin absorption in vitro and drug exposure in vivo via modulation of transporter mediated efflux. Transport studies were performed in MDCKII-MDR1 and Caco-2 cells using 3H-digoxin.
Holm, Rene; id_orcid, Abdulhussein, Ahmed A., Colak, Dilan, Nielsen, Carsten Uhd; id_orcid   +3 more
core   +1 more source

A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau

Advanced Science, EarlyView.
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun, Yang Liu, Qiuzhi Zhou, Qingyuan Hu, Weixia Wang, Yue Xiao, Jingfen Su, Guanting Liu, Miaomiao Sun, Lixia Chen, Hua Li, Ying Yang, Jian‐Zhi Wang   +12 more
wiley   +1 more source

Hypolipidemic Effect of Extra Virgin Olive Oil in Diabetic Rats

Journal of Rawalpindi Medical College, 2012
Background: To evaluate the effect of monounsaturated fatty acid and phenolic compounds enriched extra virgin olive oil on correction of dyslipidemia in diabetic rats.
Muhammad Javad Yousaf
doaj  

Biosafety evaluation of Janus Fe3O4-TiO2 nanoparticles in Sprague Dawley rats after intravenous injection

, 2018
Introduction: Newly synthesized Janus-structured Fe3O4-TiO2 nanoparticles (NPs) appear to be a promising candidate for the diagnosis and therapy of cancer.
Li, Zhen, Su, Hong, Ding, Min, Lie, Juan, Song, Xin, Iqbal, Muhammad Zubair, Wu, Aiguo, Kenston, Samuel Selorm Fiati, Zhao, Jinshun   +8 more
core  

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source