Results 201 to 210 of about 334,934 (359)

90-Day Subchronic Toxicological Evaluation of a Zylaria in Sprague Dawley Rats. [PDF]

J Toxicol
Shanmugasundaram D, Wang RA.
europepmc   +1 more source

Histopathologic Changes in Liver and Kidney Tissues from Male Sprague Dawley Rats Treated with Rhaphidophora Decursiva (Roxb.) Schott Extract [PDF]

, 2014
Siti Suriani Arsad
openalex   +1 more source

Animal models of chronic thromboembolic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu, Lin‐Chao Zhou, Xiao‐Xue Zhang, Xiao‐Yang Ren, Yi Yan, Shao‐Fei Liu   +5 more
wiley   +1 more source

Tridiet-enhanced weight gain in Sprague Dawley rats: a retrospective analysis. [PDF]

Front Nutr
Rodriguez AL, Bradfield C, Scarpa NV, Barroso BE, Fernandez MI, Cabanillas SV, Deleon-Pena A, Frias E, Agboli VI, Sarkar S, Datta S, Schiefer MA.   +11 more
europepmc   +1 more source

ANTIOXIDANT AND CHEMOTHERAPEUTIC POTENTIAL OF CURCUMA AMADA RHIZOME EXTRACT ON BENZO(A)PYRENE INDUCED CERVICAL CARCINOMA IN SPRAGUE DAWLEY RATS

, 2017
Vasundra Devi Devaraj, Suja Samiappan
openalex   +2 more sources

Metformin enhances external urethral sphincter integrity and restores continence via AMPK activation in a rat model of stress urinary incontinence

Animal Models and Experimental Medicine, EarlyView.
The pathogenesis of stress urinary incontinence (SUI) is intimately associated with injury to the external urethral sphincter (EUS). In this study, we established an SUI model induced by double vaginal distension and demonstrated that metformin treatment activated the AMPK signaling in the EUS tissue.
Yuting Xu, Xuhong Li, Alvaro Munoz, Li Jiang, Lihua Huang, Yanhua Zhou, Liping Zhu, Youbo Yang   +7 more
wiley   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Pharmacokinetics and preliminary data on safety of meloxicam subcutaneous extended-release formulation in Sprague-Dawley rats. [PDF]

Front Vet Sci
Gupta A, Akkaraju H, Vasudevan V, Turaga S, Rohan LC, Patel SK, Levinson B, Leary S, Witham S, Shaik IH, Venkataramanan R.   +10 more
europepmc   +1 more source

A high‐fat diet with vitamin D and propylthiouracil produces a pro‐atherogenic phenotype in rats

Animal Models and Experimental Medicine, EarlyView.
Male Sprague–Dawley rats received a cholesterol‐rich high‐fat diet supplemented with vitamin D and propylthiouracil for 11 weeks. The model induced dyslipidemia (increased total cholesterol/low‐density lipoprotein, decreased triglycerides), inflammation (increased interleukin‐6 and serum amyloid A), hypercalcemia, and reduced circulating endothelial ...
Angélique Lewies, Vitaris Kodogo, Johannes Frederik Wentzel, Francis Edwin Smit   +3 more
wiley   +1 more source

Acute and subacute oral toxicity assessment of Karanjin in Sprague Dawley rats. [PDF]

Toxicol Rep
Lubau NSA, Balasubramaniam V, Yap CG, Arulsamy A, Subramaniyan V.   +4 more
europepmc   +1 more source