Results 31 to 40 of about 471,278 (247)

Comparison of the effects of two anesthetics, isoflurane and urethane, on bladder function in rats

Journal of Pharmacological Sciences, 2023
We compared the effects of two anesthetics, isoflurane and urethane on bladder function in rats. Arterial pressure, cystometry (CMG), and rhythmic bladder contractions (RBCs) under isovolumetric conditions, mechanosensitive single-unit afferent ...
Naoki Aizawa, Tomoe Fujita
doaj   +1 more source

Mathematical methods and models for radiation carcinogenesis studies [PDF]

, 1986
Research on radiation carcinogenesis requires a twofold approach. Studies of primary molecular lesions and subsequent cytogenetic changes are essential, but they cannot at present provide numerical estimates of the risk of small doses of ionizing ...
A.M. Kellerer, Barlow, Bernoulli, Breslow, Broerse, Broerse, Chmelevsky, Chmelevsky, Chmelevsky, Groer, Hoel, Hulse, Kalbfleisch, Kaplan, Kellerer, Lafuma, Mole, National Academy of Sciences, National Research Council, Nelson, Recommendations of the International Commission on Radiological Protection, Rossi, Shellabarger, Shellabarger, Shellabarger, UNSCEAR-Report, Whittemore   +25 more
core   +1 more source

Genetic characterization of outbred Sprague Dawley rats and utility for genome-wide association studies

bioRxiv, 2018
Sprague Dawley (SD) rats are among the most widely used outbred laboratory rat populations. Despite this, the genetic characteristics of SD rats have not been clearly described, and SD rats are rarely used for experiments aimed at exploring genotype ...
A. Gileta, Christopher J. Fitzpatrick, Apurva S. Chitre, C. S. St. Pierre, Elizabeth Joyce, Rachael J. Maguire, Africa M. McLeod, Natalia M. Gonzales, April E. Williams, J. Morrow, T. Robinson, S. Flagel, A. Palmer   +12 more
semanticscholar   +1 more source

Subacute oral toxicity of ayurvedic anti-diabetic preparation Jambadyarista in Sprague-Dawley rats

Toxicology Reports, 2020
Background: Jambadyarista is an Ayurvedic polyherbal formulation widely prescribed by Ayurvedic practitioners for the management of diabetes and its associated complications.
Mahedi Hasan, Abdullah Al Mahmud, Md. Jahir Alam, Shafayet Ahmed Siddiqui, Md. Saiful Islam Arman, Muhammed Hasan Mahmud, Mohammad Nurul Amin, Omar Imtiaz, Masum Shahriar, Md. Jakaria   +9 more
doaj   +1 more source

Hematoxicity of amodiaquine in sprague-dawley rats

Toxicology International, 2012
The use of amodiaquine (AQ) and its associated toxic effect has been a major public health concern since cases of life-threatening agranulocytosis and hepatic toxicity were reported during its prophylactic use. The objective of this study was to evaluate the hematological safety profile of AQ therapy.Sprague-Dawley rats were randomly distributed into ...
Saka, W. A., Akhigbe, R. E., Akinola, A. O., Azeez, O. M.   +3 more
openaire   +3 more sources

Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in Sprague–Dawley rats

Nutrition and Metabolism, 2016
BackgroundNutritional ketosis induced by the ketogenic diet (KD) has therapeutic applications for many disease states. We hypothesized that oral administration of exogenous ketone supplements could produce sustained nutritional ketosis (>0.5 mM) without ...
S. Kesl, Angela Poff, Nathan P. Ward, Tina N. Fiorelli, C. Ari, A. J. Van Putten, Jacob Sherwood, Patrick Arnold, D. D'Agostino   +8 more
semanticscholar   +1 more source

Strain specific effects of low level lead exposure on associative learning and memory in rats. [PDF]

, 2017
Exposure to lead (Pb) remains a significant public health concern. Lead exposure in early life impairs the normal development of numerous cognitive and neurobehavioral processes.
Schneider, J. S., Verma, Megha
core   +2 more sources

Spontaneous Ocular Abnormalities in Sprague–Dawley Rats

Comparative Medicine, 2020
We collected historical control data derived from pretreatment ophthalmologic examinations of young (4 to 7 wk of age) Sprague–Dawley (Crl:CD[SD]) male, (2033, 42 lots) and female (1322, 32 lots) rats used in toxicity studies at our facility from 2004 through 2015.
Junya, Morita, Haruhiro, Yamashita, Kazunari, Sugihara, Masaki, Wakamatsu, Minoru, Sasaki   +4 more
openaire   +3 more sources

A Calibrated Method of Massage Therapy Decreases Systolic Blood Pressure Concomitant With Changes in Heart Rate Variability in Male Rats. [PDF]

, 2017
ObjectiveThe purpose of this study was to develop a method for applying calibrated manual massage pressures by using commonly available, inexpensive sphygmomanometer parts and validate the use of this approach as a quantitative method of applying massage
Curras-Collazo, Margarita C, Dobyns, Abigail, Gutierrez, Roberto, Jha, Vidyasagar, Kaprelian, Anthony, Spurgin, Kurt A, Wilson, Christopher G, Xu, Karen H   +7 more
core   +1 more source

Improved timed-mating, non-invasive method using fewer unproven female rats with pregnancy validation via early body mass increases [PDF]

, 2018
For studies requiring accurate conception-timing, reliable, efficient methods of detecting oestrus reduce time and costs, whilst improving welfare. Standard methods use vaginal cytology to stage cycle, and breeders are paired–up using approximately five ...
Agata K Stramek, Barnett SW, Becker JB, Crean GP, Cripps AW, Feder HH, Ferguson SA, Goldman JM, Gualillo O, Johnson ML, Johnson ML, Lopez-Luna P, Marcondes FK, Michelle L Johnson, Prager EM, Pujol E, Trujillo ML, Turner KM, Victoria J Taylor   +18 more
core   +1 more source