Spontaneous Nephroblastoma in Sprague-Dawley Rats
Pathological findings were described on nephroblastomas occurrred spontaneously in 3 young Sprague-Dawley rats. One side of kidneys was affected in each animal. Microscopically, the tumors consisted of epithelial elements showing undifferentiated to well-differentiated tubular arrangements, sometimes with glomeruloid and glomerular structures.
M, Iida, M, Yasuba, C, Itakura
openaire +3 more sources
Use Of The Prebiotic Inulin In The Prevention Of Adverse Signs Of Acute Colitis
The aim of this study was to investigate the influence of prebiotic inulin diet intervention on the activity of β-glucuronidase and counts of coliforms and lactobacilli in fresh caecal digesta, cytokine levels (IL-6, IL-8) and transcription nuclear ...
Emília Hijová +5 more
doaj +1 more source
Fatty acid synthase and adipsin mRNA levels in obese and lean JCR:LA-cp rats: effect of diet.
In Sprague-Dawley rats, fatty acid synthase (FAS) activity is suppressed by dietary fat. To test the hypothesis that a defect in regulation of de novo fatty acid synthesis exists in massive obesity, we investigated the effect of diet on FAS mRNA levels ...
G Shillabeer +5 more
doaj +1 more source
Subacute oral toxicity of ayurvedic anti-diabetic preparation Jambadyarista in Sprague-Dawley rats
Background: Jambadyarista is an Ayurvedic polyherbal formulation widely prescribed by Ayurvedic practitioners for the management of diabetes and its associated complications.
Mahedi Hasan +9 more
doaj +1 more source
A Calibrated Method of Massage Therapy Decreases Systolic Blood Pressure Concomitant With Changes in Heart Rate Variability in Male Rats. [PDF]
ObjectiveThe purpose of this study was to develop a method for applying calibrated manual massage pressures by using commonly available, inexpensive sphygmomanometer parts and validate the use of this approach as a quantitative method of applying massage
Curras-Collazo, Margarita C +7 more
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Comparison of the effects of two anesthetics, isoflurane and urethane, on bladder function in rats
We compared the effects of two anesthetics, isoflurane and urethane on bladder function in rats. Arterial pressure, cystometry (CMG), and rhythmic bladder contractions (RBCs) under isovolumetric conditions, mechanosensitive single-unit afferent ...
Naoki Aizawa, Tomoe Fujita
doaj +1 more source
Hematoxicity of amodiaquine in sprague-dawley rats
The use of amodiaquine (AQ) and its associated toxic effect has been a major public health concern since cases of life-threatening agranulocytosis and hepatic toxicity were reported during its prophylactic use. The objective of this study was to evaluate the hematological safety profile of AQ therapy.Sprague-Dawley rats were randomly distributed into ...
Saka, W. A. +3 more
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Mathematical methods and models for radiation carcinogenesis studies [PDF]
Research on radiation carcinogenesis requires a twofold approach. Studies of primary molecular lesions and subsequent cytogenetic changes are essential, but they cannot at present provide numerical estimates of the risk of small doses of ionizing ...
A.M. Kellerer +25 more
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Spontaneous Ocular Abnormalities in Sprague–Dawley Rats
We collected historical control data derived from pretreatment ophthalmologic examinations of young (4 to 7 wk of age) Sprague–Dawley (Crl:CD[SD]) male, (2033, 42 lots) and female (1322, 32 lots) rats used in toxicity studies at our facility from 2004 through 2015.
Junya, Morita +4 more
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Modeling Reveals the Dependence of Hippocampal Neurogenesis Radiosensitivity on Age and Strain of Rats [PDF]
Cognitive dysfunction following radiation treatment for brain cancers in both children and adults have been correlated to impairment of neurogenesis in the hippocampal dentate gyrus.
Cacao, Eliedonna +2 more
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