Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Microencapsulação por spray drying do extrato crioconcentrado de erva mate (Ilex paraguariensis A. St. Hill) empregando a maltodextrina como agente encapsulante [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Ciência dos Alimentos, Florianópolis, 2014.Nos diversos trabalhos científicos têm sido demonstrados os efeitos benéficos da Ilex ...
Nunes, Graciele Lorenzoni
core
The cocrystal formation of pharmaceuticals can improve the various physical properties of drugs, such as solubility, without the need for chemical modification of the drug substances.
Maho Urano +6 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Microencapsulação do óleo eugenol pelo método de spray drying [PDF]
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Curso de Química.O crescente interesse de aromas nas indústrias alimentícia, farmacêutica, cosmética entre outras, aliada a instabilidade destes compostos,
PEREIRA, Taize
core
A thermoplastic PMMA‐based photoresin enables high‐resolution DLP printing followed by solvent‐vapor smoothing. The treatment reduces staircase‐induced surface roughness from 2.33 µm to 129 nm and increases visible‐light transmittance from approximately 30% to 80%, providing a route toward transparent PMMA components for rapid prototyping and non ...
Rozhin Heydarpour +5 more
wiley +1 more source
Caracterização e atividade antimicrobiana de micropartículas carregadas de ácidos graxos de cadeia curta obtidas por spray drying [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Ciência dos Alimentos, Florianópolis, 2014.No presente trabalho micropartículas contendo ácidos graxos de cadeia curta (AGCC) foram
Luchtenberg, Rafael
core
Developments in the formulation and delivery of spray dried vaccines
Spray drying is a promising method for the stabilization of vaccines, which are usually formulated as liquids. Usually, vaccine stability is improved by spray drying in the presence of a range of excipients.
Gaurav Kanojia +5 more
doaj +1 more source
A user-friendly model for spray drying to aid pharmaceutical product development. [PDF]
The aim of this study was to develop a user-friendly model for spray drying that can aid in the development of a pharmaceutical product, by shifting from a trial-and-error towards a quality-by-design approach.
Niels Grasmeijer +3 more
doaj +1 more source

