Results 31 to 40 of about 1,049,838 (245)

Damage to Myelin and Oligodendrocytes: A Role in Chronic Outcomes Following Traumatic Brain Injury?

Brain Sciences, 2013
There is increasing evidence in the experimental and clinical traumatic brain injury (TBI) literature that loss of central myelinated nerve fibers continues over the chronic post-traumatic phase after injury.
William L. Maxwell
doaj   +1 more source

A Case Report: Isolated Pontine Lesion in Hypertensive of a Pregnant Patient with Idiopathic Thrombocytopenia

European Medical Journal, 2020
Posterior reversible encephalopathy syndrome (PRES) is a neuroradiologic diagnosis characterised by headache, seizures, altered mental status, and a spectrum of visual deficits ranging from visual neglect to cortical blindness.
Ilknur Yardimci, Mehmet Tunc, Bahar Say, Cemile Dayangan Sayan, Mirace Yasemin Karadeniz Bilgili, Selim Yalcin, Ozlem Coskun   +6 more
doaj  

Oxcarbazepine does not suppress cortical spreading depression

, 2010
Background: Cortical spreading depression is the electrophysiological substrate of migraine aura, and may trigger headache. Recently, chronic treatment with five migraine prophylactic drugs was shown to suppress cortical spreading depression ...
Ergin Dileköz, Chiho Kudo, Ulrike Hoffmann, Dilekoez, ERGİN, Hoffmann, Ulrike, Ayata, Cenk, Cenk Ayata, Kudo, Chiho   +7 more
core   +1 more source

Spreading depression sends microglia on Lévy flights. [PDF]

PLoS ONE, 2011
Spreading depression (SD) is thought to cause migraine aura, and perhaps migraine, and includes a transient loss of synaptic activity preceded and followed by increased neuronal excitability.
Yelena Y Grinberg, John G Milton, Richard P Kraig   +2 more
doaj   +1 more source

Electrical and Vascular Concomitants of Spreading Depression

, 1957
Spreading depression is accompanied by a slow potential change, a drop in cortical conductivity and by vascular changes. The latter were investigated in histological preparations of cortex frozen while a spreading depression was in progress.
Sidney Ochs, A. Van Harreveld
core   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Astrocytes as critical players of the fine balance between inhibition and excitation in the brain: spreading depolarization as a mechanism to curb epileptic activity

Frontiers in Network Physiology
Spreading depolarizations (SD) are slow waves of complete depolarization of brain tissue followed by neuronal silencing that may play a role in seizure termination. Even though SD was first discovered in the context of epilepsy research, the link between
Rune Enger, Kjell Heuser
doaj   +1 more source

ROS/TRPA1/CGRP signaling mediates cortical spreading depression

The Journal of Headache and Pain, 2019
Objectives The transient receptor potential ankyrin A 1 (TRPA1) channel and calcitonin gene-related peptide (CGRP) are targets for migraine prophylaxis.
Liwen Jiang, Dongqing Ma, Blair D. Grubb, Minyan Wang   +3 more
doaj   +1 more source

Coupling of capillary RBC flow failure with neuronal depolarization [PDF]

, 2009
RBC (oxygen-carrier) behaviour in the cerebrocortical microvasculature during K^+^-induced cortical spreading depression (CSD) was examined in urethane-anesthetized male Wistar rats (n=10).
Miyuki Unekawa, Minoru Tomita, Haruki Toriumi, Norihiro Suzuki, Yutaka Tomita   +4 more
core  

Cortical Discontinuity and Propagation of Spreading Depression

, 1955
The transmissibility of spreading depression across a cut severing all layers of the cortex was investigated in preparations in which 3 weeks to 3 months was allowed for healing of such an injury.
E. A. Dernburg, G. Terres, A. Van Harreveld   +2 more
core   +1 more source