Results 11 to 20 of about 1,049,838 (245)

Diversity of cortical activity changes beyond depression during Spreading Depolarizations

open access: yesNature Communications, 2023
Spreading depolarizations (SDs) are classically thought to be associated with spreading depression of cortical activity. Here, we found that SDs in patients with subarachnoid hemorrhage produce variable, ranging from depression to booming, changes in ...
Azat Nasretdinov   +8 more
doaj   +2 more sources

Cortical spreading depression-induced preconditioning in the brain

open access: yesNeural Regeneration Research, 2016
Cortical spreading depression is a technique used to depolarize neurons. During focal or global ischemia, cortical spreading depression-induced preconditioning can enhance tolerance of further injury. However, the underlying mechanism for this phenomenon
Ping-ping Shen   +8 more
doaj   +2 more sources

Data of ascending cortical vein occlusion induced spreading depression

open access: yesData in Brief, 2018
The data presented in this article are related to the research article entitled “Microembolism of single cortical arterioles can induce spreading depression and ischemic injury; a potential trigger for migraine and related MRI lesions” (Donmez-Demir et ...
Buket Dönmez-Demir   +2 more
doaj   +2 more sources

Migraine Visual Aura and Cortical Spreading Depression-Linking Mathematical Models to Empirical Evidence. [PDF]

open access: yesVision (Basel), 2021
This review describes the subjective experience of visual aura in migraine, outlines theoretical models of this phenomenon, and explores how these may be linked to neurochemical, electrophysiological and psychophysical differences in sensory processing ...
O'Hare L, Asher JM, Hibbard PB.
europepmc   +2 more sources

Repetitive spreading depolarization induces gene expression changes related to synaptic plasticity and neuroprotective pathways

open access: yesFrontiers in Cellular Neuroscience, 2023
Spreading depolarization (SD) is a slowly propagating wave of profound depolarization that sweeps through cortical tissue. While much emphasis has been placed on the damaging consequences of SD, there is uncertainty surrounding the potential activation ...
Michela Dell’Orco   +6 more
doaj   +1 more source

Neuroprotection and acidosis induced by cortical spreading depression [PDF]

open access: yesNeuropsychiatric Disease and Treatment, 2016
Kenneth K Kwong, Suk-tak Chan Department of Radiology, MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, USA We read with interest the article “Cortical spreading ...
Kwong KK, Chan ST
doaj   +2 more sources

Biomaterials to Neuroprotect the Stroke Brain: A Large Opportunity for Narrow Time Windows

open access: yesCells, 2020
Ischemic stroke represents one of the most prevalent pathologies in humans and is a leading cause of death and disability. Anti-thrombolytic therapy with tissue plasminogen activator (t-PA) and surgical thrombectomy are the primary treatments to ...
Daniel González-Nieto   +5 more
doaj   +1 more source

Migraine Aura, Transient Ischemic Attacks, Stroke, and Dying of the Brain Share the Same Key Pathophysiological Process in Neurons Driven by Gibbs–Donnan Forces, Namely Spreading Depolarization

open access: yesFrontiers in Cellular Neuroscience, 2022
Neuronal cytotoxic edema is the morphological correlate of the near-complete neuronal battery breakdown called spreading depolarization, or conversely, spreading depolarization is the electrophysiological correlate of the initial, still reversible phase ...
Coline L. Lemale   +17 more
doaj   +1 more source

Understanding Spreading Depression from Headache to Sudden Unexpected Death

open access: yesFrontiers in Neurology, 2018
Spreading depression (SD) is a neurophysiological phenomenon characterized by abrupt changes in intracellular ion gradients and sustained depolarization of neurons.
Olga Cozzolino   +7 more
doaj   +1 more source

Nitric oxide formation during cortical spreading depression is critical for rapid subsequent recovery of ionic homeostasis [PDF]

open access: yes, 2003
NoCortical spreading depression (CSD) is a temporary disruption of local ionic homeostasis that propagates slowly across the cerebral cortex. Cortical spreading depression promotes lesion progression in experimental stroke, and may contribute to the ...
Urenjak, Jutta A.   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy