Results 71 to 80 of about 437,891 (285)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Qualitative analysis of a mathematical model for malaria transmission and its variation
Electronic Journal of Differential Equations, 2016 In this article we consider a mathematical model of malaria transmission. We investigate both a reduced model which corresponds to the situation when the infected mosquito population equilibrates much faster than the human population and the full ...
Zhenbu Zhang, Tor A. Kwembe
doaj
Supercritical spatial SIR epidemics: Spreading speed and herd immunity
The Annals of Applied ProbabilityWe study supercritical spatial SIR epidemics on $\mathbb{Z}^2\times \{1,2,\ldots, N\}$, where each site in $\mathbb{Z}^2$ represents a village and $N$ stands for the village size. We establish several key asymptotic results as $N\to\infty$. In particular, we derive the probability that the epidemic will last forever if the epidemic is started by one ...
Zheng, Xinghua, Zhu, Qingsan
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Distinct Spreading Speeds in a Lotka–Volterra Cooperative System
Journal of Mathematics, 2020 This paper deals with the spreading speeds in the classical Lotka–Volterra cooperative system, of which the bounds have been studied earlier. By introducing an auxiliary cooperative system and constructing an upper solution, we obtain a sufficient condition to confirm two distinct spreading speeds of unknown functions.
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Modeling and Simulating an Epidemic in Two Dimensions with an Application Regarding COVID-19
ComputationWe derive a reaction–diffusion model with time-delayed nonlocal effects to study an epidemic’s spatial spread numerically. The model describes infected individuals in the latent period using a structured model with diffusion.
Khalaf M. Alanazi
doaj +1 more source
The method of calculating the parameters of the materials delivery mechanism of the technological materials distributor [PDF]
BIO Web of ConferencesIn this article, road services use technological materials (sand- salt mixture) to remove snow, ice and ice from roads in the winter season. allows to reduce losses.
Turdibekov Saloxiddin +3 more
doaj +1 more source
On the Speed of Spread for Fractional Reaction‐Diffusion Equations [PDF]
International Journal of Differential Equations, 2009 The fractional reaction diffusion equation ∂tu + Au = g(u) is discussed, where A is a fractional differential operator on ℝ of order α ∈ (0, 2), the C1 function g vanishes at ζ = 0 and ζ = 1, and either g ≥ 0 on (0, 1) or g < 0 near ζ = 0. In the case of nonnegative g, it is shown that solutions with initial support on the positive half axis spread ...
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