Results 1 to 10 of about 158,509 (197)

Decreased Sputum Type-2 Gene Expression in COPD Current Smokers [PDF]

International Journal of COPD
Thomas Southworth,1,2 Andrew Higham,1 Augusta Beech,1,2 Jian Li,1 Sophie Wolosianka,2 Dave Singh1,2 1Division of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health ...
Southworth T, Higham A, Beech A, Li J, Wolosianka S, Singh D   +5 more
doaj   +2 more sources

Microbial Landscape and Antibiotic-Susceptibility Profiles of Microorganisms in Patients with Bacterial Pneumonia: A Comparative Cross-Sectional Study of COVID-19 and Non-COVID-19 Cases in Aktobe, Kazakhstan

Antibiotics, 2023
This cross-sectional study investigated the microbial landscape and antibiotic-resistance patterns in patients with bacterial pneumonia, with a focus on the impact of COVID-19.
Nurgul Ablakimova, Aigul Z. Mussina, Gaziza A. Smagulova, Svetlana Rachina, Meirambek S. Kurmangazin, Aigerim Balapasheva, Dinara Karimoldayeva, Afshin Zare, Mahdi Mahdipour, Farhad Rahmanifar   +9 more
doaj   +1 more source

Au nanorod assembly for sensitive SERS detection of airway inflammatory factors in sputum

Frontiers in Bioengineering and Biotechnology, 2023
In this paper, we demonstrate a surface-enhanced Raman spectroscopy (SERS) biosensor based on the self-assembly of gold nanorods (AuNRs) for the specific detection of airway inflammatory factors in diluted sputum.
An-qi Yang, An-qi Yang, Wentong Zheng, Xiaoyang Chen, Jiayin Wang, Shuang Zhou, Hongzhi Gao, Hongzhi Gao   +7 more
doaj   +1 more source

Sputum Galactomannan Has Utility in the Diagnosis of Chronic Pulmonary Aspergillosis

Journal of Fungi, 2022
Diagnosis of pulmonary aspergillosis (PA), a fungal disease caused by Aspergillus species, is challenging since symptoms are unspecific. The galactomannan (antigen secreted by Aspergillus species) test in bronchoalveolar lavage (BAL) fluid is a valuable ...
Ali Nuh, Newara Ramadan, Anand Shah, Darius Armstrong-James   +3 more
doaj   +1 more source

Methodological Aspects of Induced Sputum

Advances in Respiratory Medicine, 2023
We aimed to conduct a state-of-the-art review of the current literature and offer further insights into the methodological aspects concerning induced sputum.
Silvano Dragonieri, Andras Bikov, Alessandro Capuano, Simone Scarlata, Giovanna Elisiana Carpagnano   +4 more
doaj   +1 more source

Gram Stain and Culture of Sputum Samples Detect Only Few Pathogens in Community-Acquired Lower Respiratory Tract Infections: Secondary Analysis of a Randomized Controlled Trial

Diagnostics, 2023
Identification of the bacterial etiology of lower respiratory tract infections (LRTI) is crucial to ensure a narrow-spectrum, targeted antibiotic treatment.
Mariana B. Cartuliares, Helene Skjøt-Arkil, Christian B. Mogensen, Thor A. Skovsted, Steen L. Andersen, Andreas K. Pedersen, Flemming S. Rosenvinge   +6 more
doaj   +1 more source

Specific associations between fungi and bacteria in broncho-alveolar aspirates from mechanically ventilated intensive care unit patients

Virulence, 2022
The detection of fungi in the human respiratory tract may represent contamination, colonization or a respiratory infection. To develop effective management strategies, a more accurate and comprehensive understanding of the lung fungal microbiome is ...
Arezoo Shajiei, Lei Liu, Jolien Seinen, Willem Dieperink, Sven Hammerschmidt, Jan Maarten van Dijl, Hermie J.M. Harmsen   +6 more
doaj   +1 more source

An Innovative Protocol for Metaproteomic Analyses of Microbial Pathogens in Cystic Fibrosis Sputum

Frontiers in Cellular and Infection Microbiology, 2021
Hallmarks of cystic fibrosis (CF) are increased viscosity of mucus and impaired mucociliary clearance within the airways due to mutations of the cystic fibrosis conductance regulator gene.
Alexander C. Graf, Johanna Striesow, Jan Pané-Farré, Thomas Sura, Martina Wurster, Michael Lalk, Dietmar H. Pieper, Dörte Becher, Barbara C. Kahl, Katharina Riedel   +9 more
doaj   +1 more source

Nontuberculous mycobacteria isolation from sputum specimens: A retrospective analysis of 1061 cases

International Journal of Mycobacteriology, 2023
Background: In recent years, with the development of laboratory methods, the frequency of nontuberculosis mycobacteria (NTM) infections has increased. The primary aim of this study was to evaluate the clinical significance of therapeutic drug monitoring (
Aylin Babalik, Emine Nur Koç, Hamide Gül Sekerbey, Gül Erdal Dönmez, Ahmet Balikçi, Zeki Kiliçaslan   +5 more
doaj   +1 more source

Mapping bacterial diversity and metabolic functionality of the human respiratory tract microbiome

Journal of Oral Microbiology, 2022
Background The Human Respiratory Tract (HRT) is colonized by various microbial taxa, known as HRT microbiota, in a manner that is indicative of mutualistic interaction between such microorganisms and their host.Aim To investigate the microbial ...
Leonardo Mancabelli, Christian Milani, Federico Fontana, Gabriele Andrea Lugli, Chiara Tarracchini, Francesca Turroni, Douwe van Sinderen, Marco Ventura   +7 more
doaj   +1 more source