Results 71 to 80 of about 353,966 (351)

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

Advanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao, Victor Fernandez‐Gonzalez, Xiaochuan Wang, Blake Pylipow, Claudia Herrera, Xiaohu Xia   +5 more
wiley   +1 more source

Association between fractional exhaled nitric oxide, sputum induction and peripheral blood eosinophil in uncontrolled asthma

Allergy, Asthma & Clinical Immunology, 2018
BackgroundThe fractional exhaled nitric oxide (FeNO) and blood eosinophils are biomarkers of eosinophilic airway inflammation used in the diagnosis and management of asthma, although induced sputum is the gold standard test for phenotypic asthma ...
Jie Gao, Feng-Qin Wu
semanticscholar   +1 more source

Mechanisms of Mitochondrial Toxicity and Cytotoxicity Caused by Pseudomonas aeruginosa Pyocyanin in Human Nasal Epithelial Cells

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson, April Park, Yobouet Ines Kouakou, Zoey A. Miller, Nabil F. Darwich, Nithin D. Adappa, James N. Palmer, Ryan M. Carey, Robert J. Lee   +8 more
wiley   +1 more source

Respiratory Bacterial Culture Sampling in Expectorating and Non-expectorating Patients With Cystic Fibrosis

Frontiers in Pediatrics, 2018
Purpose: Different respiratory sampling methods exist to identify lower airway pathogens in patients with cystic fibrosis (CF), of which bronchoalveolar lavage (BAL), and expectorated sputum are considered the “gold standard.” Because BAL cannot be ...
Hanneke Eyns, Hanneke Eyns, Hanneke Eyns, Denis Piérard, Elke De Wachter, Leo Eeckhout, Peter Vaes, Peter Vaes, Anne Malfroot   +8 more
doaj   +1 more source

Sputum biomarkers in IPF: Evidence for raised gene expression and protein level of IGFBP-2, IL-8 and MMP-7

PLoS ONE, 2017
Background Idiopathic pulmonary fibrosis (IPF) is a rare lung disease of unknown origin leading rapidly to death. This paper addresses the issue of whether sputum induction is a suitable tool to study respiratory tract inflammation and potential ...
J. Guiot, M. Henket, J. Corhay, C. Moermans, R. Louis   +4 more
semanticscholar   +1 more source

The infectiousness of tuberculosis patients coinfected with HIV [PDF]

, 2008
The current understanding of airborne tuberculosis (TB) transmission is based on classic 1950s studies in which guinea pigs were exposed to air from a tuberculosis ward.
A. Roderick Escombe, Alland, Armando Gonzalez, Balasubramanian, Beggs, Behr, Bock, Bonnet, Borgdorff, Burgos, Calder, Capewell, Carlos Martínez, Carlton A Evans, Catanzaro, Catherine J Noakes, Caviedes, Caviedes, Cox, Cruciani, David A. J Moore, Desjardin, Eduardo Ticona, Escombe, Escombe, Escombe, Espinal, Fennelly, Fennelly, Gandhi, Garcí, Jindani, Jon S Friedland, Kamerbeek, Loudon, Luz Caviedes, Malasky, Marcos Navincopa, Nardell, Palmero, Patricia Sheen, Peter Wilson, Riley, Riley, Riley, Robert H Gilman, Rose, Rouillon, Shamputa, Snider, Sultan, Teixeira, van Soolingen, William Pan   +53 more
core   +7 more sources

The SNP rs13147758 in the HHIP Gene Is Associated With COPD Susceptibility, Serum, and Sputum Protein Levels in Smokers

Frontiers in Genetics, 2020
BackgroundGenetic association studies have identified single nucleotide polymorphisms (SNPs) related to chronic obstructive pulmonary disease (COPD) susceptibility.
Alejandro Ortega-Martínez, Alejandro Ortega-Martínez, Gloria Pérez-Rubio, Enrique Ambrocio-Ortiz, Karol J. Nava-Quiroz, Rafael de Jesus Hernández-Zenteno, Edgar Abarca-Rojano, Sebastián Rodríguez-Llamazares, Andrea Hernández-Pérez, Leonor García-Gómez, Alejandra Ramírez-Venegas, Ramcés Falfán-Valencia   +11 more
doaj   +1 more source

Examination of Acid-Fast Bacilli in Sputum Using Modified Light Microscope with Homemade Light Emitting Diode Additional Attachment [PDF]

, 2011
Typical clinical symptoms and chest X-ray is a marker of Tuberculosis (TB) sufferers. However, the diagnosis of TB in adults should be supported by microscopic examination.
Ibrahim, A. S. (Anwar), Karuniawati, A. (Anis), Prawoto, P. (Prawoto), Riyanto, S. A. (Subari), Tedjo, A. (Aryo)   +4 more
core  

Comparison of sputum collection methods for tuberculosis diagnosis: a systematic review and pairwise and network meta-analysis

Lancet Global Health, 2017
Summary Background The performance of laboratory tests to diagnose pulmonary tuberculosis is dependent on the quality of the sputum sample tested. The relative merits of sputum collection methods to improve tuberculosis diagnosis are poorly characterised.
S. Datta, L. Shah, R. Gilman, C. Evans
semanticscholar   +1 more source

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source