Results 91 to 100 of about 42,005 (248)

Enhanced Squalene Production by Thraustochytrium sp. RT2316-16 by Polyphenols from Barley Bagasse

open access: yesFermentation
Squalene, a hydrocarbon with several industrial applications, is obtained from plants, animals, and microorganisms. Oleaginous thraustochytrids are also potential sources of squalene.
Paris Paredes   +2 more
doaj   +1 more source

Transglutaminase‐mediated cytokeratin modifications implicated in bile‐acid‐induced hepatocyte death

open access: yesThe FEBS Journal, EarlyView.
Cholestasis and bile‐acid exposure enhance expression and activity of protein crosslinking enzymes TG1 and TG2 in hepatocytes. Substrate proteins were identified by mass spectrometry using biotin‐labeled peptides (pepK5/pepT26) or amine donor (biotinylated pentylamine; BPA). Crosslinking‐induced aggregation and fragmentation of keratin 18 and 8 (K18/K8)
Hideki Tatsukawa   +4 more
wiley   +1 more source

Metabolic engineering and adaptive laboratory evolution enhance squalene production in Yarrowia lipolytica

open access: yesSynthetic and Systems Biotechnology
Squalene, a multifunctional natural compound with diverse bioactivities, has significant potential in the nutraceutical and health industries. Microbial synthesis using engineered cell factories represents a sustainable alternative to conventional ...
Qiao-Qin Zhao   +10 more
doaj   +1 more source

Streaming potential analysis of hair variation: Ethnicities and environmental exposures

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Ethnicity and weathering shape electrokinetic behaviour and particle deposition in hair. ζ‐potential magnitudes ranked Caucasian > Indian > Chinese with no significant root‐tip variations. Deposition patterns generally correlate with ζ‐potential but differ by ethnicity, implicating other factors.
Huijun Phoebe Tham   +2 more
wiley   +1 more source

Low-energy photoelectron transmission through aerosol overlayers

open access: yes, 2017
The transmission of low-energy ( 20nm) are presumably a consequence of distorted core-shell structures.
Bohren C. F.   +3 more
core   +1 more source

Microbial community dynamics during composting of sewage sludge and straw studied through phospholipid and neutral lipid analysis [PDF]

open access: yes, 2008
The composting process involves a succession of different communities of microorganisms that decompose the initial material, transforming it into a stable final product. In thiswork, the levels of phospholipid fatty acid (PLFA), neutral lipid fatty acid (
Amir, Soumia   +5 more
core   +3 more sources

Hair Loss from Squalene.

open access: yesExperimental Biology and Medicine, 1951
SummarySqualene, an isoprene polymer occurring in normal human sebum, caused complete reversible local depilation in rabbits and guinea pigs after a single topical application. No hair loss was observed in mice. In vitro, squalene inactivated the free sulfhydryl groups of glutathione, human epidermis and mouse liver and inhibited succinic dehydrogenase
openaire   +2 more sources

Engineering Cyanobacteria for High‐Yield Photosynthetic Isoprene Production With Long‐Term Phenotypic Stability

open access: yesPlant Biotechnology Journal, EarlyView.
Center: Cyanobacterial isoprene production from CO2 and sunlight. Top: CRISPR‐editing for generation of markerless production strains. Top right: Long‐term production assay for strain stability assessment. Bottom right: Engineering of MEP pathway and surrounding metabolism for bottleneck idenfication. Bottom left: Relief of bottleneck by overproduction
Kim N. Janssen   +6 more
wiley   +1 more source

Regulation of squalene epoxidase activity in rat liver.

open access: yesJournal of Lipid Research, 1990
Regulation of squalene epoxidase activity was examined in rat hepatic microsomes. The hepatic squalene epoxidase activity was high in the dark period and low in the light period.
T Satoh, Y Hidaka, T Kamei
doaj   +1 more source

Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin. [PDF]

open access: yes, 2006
3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase is a critical enzyme in the mevalonate pathway that regulates the biosynthesis of cholesterol as well as isoprenoids that mediate the membrane association of certain GTPases.
Dunn, Shannon E   +6 more
core   +1 more source

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