Results 191 to 200 of about 42,005 (248)

Investigating the effects of circadian rhythm on the human skin lipidome.

Analyst
Géhin C, Witter AV, Wang L, Barran PE, Fowler SJ, Trivedi DK.   +5 more
europepmc   +1 more source

Comparative analyses of active and flavor components and anti-inflammatory capacities of olive oil varieties. [PDF]

Curr Res Food Sci
Wu B, Hu Q, Hao J, Li C, Cao C, Lu B, Pei D, Kan H, Liu Y, Li F.   +9 more
europepmc   +1 more source

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Squalane and Squalene

International Journal of Toxicology, 2023
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 1982, along with updated information regarding product types and concentrations of use, and confirmed that Squalane and Squalene are safe as cosmetic ingredients in the practices of use and concentration as described in this report.
Monice, Fiume, Wilma F, Bergfeld, Donald V, Belsito, Ronald A, Hill, Curtis D, Klaassen, Daniel C, Liebler, James G, Marks, Ronald C, Shank, Thomas J, Slaga, Paul W, Snyder, Bart, Heldreth   +10 more
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Squalene synthetase

Molecular and Cellular Biochemistry, 1979
In the first part of the review the background to the discovery of the asymmetric synthesis of squalene from two molecules of farnesyl pyrophosphate and NADPH is described, then the stereochemistry of the overall reaction is summarized. The complexity of the biosynthesis of squalene by microsomal squalene synthetase demanded the existence of some ...
G, Popják, W S, Agnew
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Vaccination, squalene and anti-squalene antibodies: Facts or fiction?

European Journal of Internal Medicine, 2010
Squalene, a hydrocarbon obtained for commercial purposes primarily from shark liver oil and other botanic sources, is increasingly used as an immunologic adjuvant in several vaccines, including seasonal and the novel influenza A (H1N1) 2009 pandemic flu vaccines.
Giuseppe, Lippi, Giovanni, Targher, Massimo, Franchini   +2 more
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Squalene in Petroleum Asphaltenes

Science, 1981
Squalene, 2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene, a new biological marker, has been detected in various petroleum asphaltenes and their pyrolysis products. Since squalene is the most common triterpenoid in nature and the biological precursor of the important tetra- and pentacyclic triterpane markers, its detection in asphaltene ...
N, Samman, T, Ignasiak, C J, Chen, O P, Strausz, D S, Montgomery   +4 more
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Squalene Synthase Inhibitors

Current Pharmaceutical Design, 1996
Abstract: Squalene synthase catalyzes the reductive dimerization of famesyl diphosphate (C-15) to form squalene, the C-30 polyisoprene precursor to cholesterol. In recent years, the search for inhibitors of squalene synthase for use as antihypercholesterolemic agents has intensified.
Scott A. Biller, Kent Neuenschwander, Mitree M. Ponpipomt, C. Dale Poulter   +3 more
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An NMR and molecular mechanics study of squalene and squalene derivatives

Chemistry and Physics of Lipids, 1994
Various squalene derivatives, including squalene, squalene 2,3-epoxide (monoepoxide, SQME), squalene 2,3;22,23-diepoxide (SQDE), 2-aza-2,3-dihydrosqualene (SQN) and 2-aza-2,3-dihydrosqualene N-oxide (SQNO), were studied in chloroform solutions using ID high-resolution 1H spectra and 13C longitudinal relaxation studies, 2D proton NOESY and COSY and 2D ...
Lionello Pogliani, CERUTI, Maurizio, RICCHIARDI, Gabriele, Davide Viterbo   +3 more
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Squalene: potential chemopreventive agent

Expert Opinion on Investigational Drugs, 2000
Squalene is a triterpene that is an intermediate of the cholesterol biosynthesis pathway and it can be obtained from the diet. Olive oil contains 0.2-0.7% squalene. The average intake of squalene is 30 mg/day in the United States, however, when consumption of olive oil is high, the intake of squalene can reach 200-400 mg/day as observed in ...
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[9] Synthesis of labeled squalene and squalene 2,3-oxide

1969
Publisher Summary Squalene 2,3-oxide is an intermediate in the enzymatic cyclization of squalene to lanosterol, and, in consequence, this aspect of steroid and terpenoid biogenesis has become the center of renewed interest. This chapter describes the improved methods for the chemical synthesis of labeled squalene and squalene 2,3-oxide.
R.G. Nadeau, R.P. Hanzlik
openaire   +1 more source