Results 201 to 210 of about 153,973 (298)

Beyond Skin and Eyes: The Medical and Social Burden of Oculocutaneous Albinism in Africa: A Narrative Review

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Oculocutaneous albinism (OCA) is a genetic disorder found worldwide, but its impact is particularly pronounced in the African continent. This results from both a higher prevalence and the persistent myths and superstitions surrounding the condition in many African communities.
Rebecca Donadoni   +3 more
wiley   +1 more source

Sun Protection Behaviours in Skin Cancer Survivors: A Systematic Review and Meta‐Analysis

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Skin cancer, including melanoma and non‐melanoma skin cancer (NMSC), is one of the most prevalent cancers worldwide. Although sun protection behaviors, such as sunscreen use, protective clothing, and shade‐seeking, are crucial in preventing skin cancer recurrence and secondary malignancies, adherence to these behaviors among ...
Shubham Kumar   +3 more
wiley   +1 more source

The Physician Global Assessment as a Proxy for Photoaging: Validation in an Observational Real‐World Cohort Using SCINEXA as the Reference Standard

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Photoaging is a chronic skin condition caused by cumulative ultraviolet exposure superimposed on intrinsic aging. Although the SCore of INtrinsic and EXtrinsic skin Aging (SCINEXA) is a validated multidimensional instrument for assessing photoaging, the Physician Global Assessment (PGA) is a simpler clinician‐reported measure whose ...
Ewout Baerveldt   +6 more
wiley   +1 more source

Rhaponticin Blocks Glycolysis‐Mediated Histone Lactylation to Suppress Tongue Squamous Cell Carcinoma via HIF‐1α Activity Inhibition

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma (TSCC) often develops therapeutic resistance. Metabolic reprogramming, particularly the glycolysis/lactate/histone lactylation axis, is a critical driver of tumor progression and therapy resistance. This study investigated the anti‐tumor mechanism of Rhaponticin (Rha), focusing on the metabolic/epigenetic axis ...
Yuan Wu   +7 more
wiley   +1 more source

Heterogeneity Analyzed by CT‐Based Habitat Analysis for Clinical Management of Cancers: A Narrative Review

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tumors are highly heterogeneous, and whole‐lesion radiomics analysis is a popular method for extracting texture features that reflect this heterogeneity, which can be used to build models for cancer diagnosis, staging, therapy response evaluation, and prognosis prediction.
Yang Zhang   +2 more
wiley   +1 more source

Squamous cell carcinoma of the head and neck.

open access: yesJournal of B.U.ON. : official journal of the Balkan Union of Oncology, 2002
openaire   +2 more sources

Triptolide Suppresses Tongue Squamous Cell Carcinoma Progression via PI3K–AKT Pathway Inhibition: An Integrative Network Pharmacology and Experimental Validation Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma, the most aggressive subtype of oral squamous cell carcinoma, which is associated with high mortality, frequent recurrence, and early lymph‐node metastasis. Triptolide, a bioactive diterpenoid from Tripterygium wilfordii, exhibits broad anticancer activity.
Shan‐Shan Wang   +3 more
wiley   +1 more source

Diagnostic Delay of Unilateral Facial Paralysis Caused by Occult Malignancy: A Scoping Review

open access: yesThe Laryngoscope, EarlyView.
This scoping review of 27 studies (66 patients) characterizes unilateral facial paralysis caused by occult malignancy, a rare entity marked by a mean diagnostic delay of 21 months and initially negative imaging in 89% of cases. Progressive paralysis, lack of recovery, trigeminal or additional cranial nerve involvement, and a history of regional skin ...
Kai C. Kokesh   +4 more
wiley   +1 more source

Effect of Notch1 on Vocal Fold Re‐Epithelization After Acute Injury

open access: yesThe Laryngoscope, EarlyView.
Conditional deletion of Notch1 in Lrig1‐expressing vocal fold epithelial cells impaired re‐epithelialization following naphthalene injury, resulting in sustained basal cell proliferation, abnormal epithelial differentiation, and prolonged inflammatory cell infiltration.
Jie Cai   +2 more
wiley   +1 more source

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