Depth of Invasion Predicts Vocal Fold Motility and Muscle Invasion in Glottic Carcinoma
To determine whether depth of invasion (DOI) provides an objective surrogate for vocal fold motility and vocal muscle invasion in glottic squamous cell carcinoma. Methods and Results: In derivation and external validation cohorts, radiologic DOI strongly correlated with pathologic DOI and accurately predicted altered vocal fold motility and muscle ...
Elisa Bellini +22 more
wiley +1 more source
An Ulcerated Nodule on the Scalp
JEADV Clinical Practice, EarlyView.
Zainab Asghar +2 more
wiley +1 more source
Effects of NDURE on Timely Adjuvant Radiotherapy in HNSCC: Subgroup Analysis of an RCT
In this subgroup analysis of a randomized clinical trial of 145 patients with locally advanced head and neck squamous cell carcinoma, the enhanced navigation‐based intervention NDURE improved initiation of timely postoperative radiation therapy (PORT) relative to usual care across nearly all demographic and clinical subgroups, including patients with ...
Jonathan M. Hughes +20 more
wiley +1 more source
Bilateral Ophthalmoplegia After Neoadjuvant Pembrolizumab for Oral Cavity Squamous Cell Carcinoma
The role of immune checkpoint inhibition (ICI) therapy in the treatment of head and neck squamous cell carcinoma (HNSCC) is expanding with increased utilization of neoadjuvant and adjuvant pembrolizumab in the setting of locally advanced disease. This report describes the presentation and management of the first known case of pembrolizumab‐induced ...
Leonard E. Estephan +3 more
wiley +1 more source
The Subhyoid Approach for Base of Tongue Tumors: Description of A Novel Surgical Technique
The sub‐hyoid approach is a novel open surgical technique for selected deeply infiltrative base of tongue tumors, providing direct access and allowing full‐thickness resection while preserving the tongue neurovascular structures. Thyro‐hyoido‐pexy restores hyo‐laryngeal suspension without flap reconstruction, with the aim of preserving swallowing ...
Livio Presutti +6 more
wiley +1 more source
Contemporary Treatment Patterns in Surgically Treated Temporal Bone Cancer
In a national cohort of 811 surgically treated temporal bone cancer patients, adjuvant radiation therapy was the most frequently utilized postoperative treatment (20.3%), while chemotherapy and immunotherapy were used far less frequently. Multimodal treatment, particularly combined parotidectomy and neck dissection, was strongly associated with higher ...
Raquel Rowell +4 more
wiley +1 more source
Laryngeal Carcinoma Treatment Outcomes in Female Patients
With an increasing incidence of laryngeal cancer in female patients, characteristics unique to female patients should be considered when recommending therapy. This is a retrospective cohort study examining these characteristics, such as preoperative status, staging at presentation, treatment selection, and outcomes.
Carly A. Clark +8 more
wiley +1 more source
Complete Response Demonstrated by [<sup>11</sup>C]methionine-PET Imaging of a Patient With Squamous-cell Carcinoma of the Tongue Treated With Chemotherapy, Immunotherapy and Methionine Restriction Without Radiation or Surgery: A Potential New Low-toxicity Treatment Paradigm for a Recalcitrant Disease. [PDF]
Ishiguro T +8 more
europepmc +1 more source
Occupational HPV Exposure in Otolaryngology: A Scoping Review of Detection, Risk, and Prevention
This scoping review identified 10 studies evaluating occupational HPV exposure in otolaryngology. HPV DNA was detected in surgical plume following some HPV‐related procedures, including up to 56.7% of CO2 laser plume samples, while the only study assessing oral HPV among exposed clinicians reported a prevalence of 2.2%, not exceeding that of the ...
Ying Jie Li +2 more
wiley +1 more source

