Results 231 to 240 of about 153,973 (298)

Oncologic Outcomes in p16‐Positive Oropharyngeal Squamous Cell Carcinoma With Extranodal Extension

open access: yesThe Laryngoscope, EarlyView.
In this retrospective cohort of 232 surgically treated patients with p16‐positive oropharyngeal squamous cell carcinoma, survival outcomes were high and recurrence rates low. Macroscopic histopathologic extranodal extension (pENE) demonstrated lower 5‐year overall survival compared to microscopic pENE (80.2% vs. 89.8%), although this difference was not
Victoria Taylor   +6 more
wiley   +1 more source

Office‐Based Transoral Ultrasonography in the Diagnostic Workup of Oropharyngeal Cancer

open access: yesThe Laryngoscope, EarlyView.
This article demonstrates how to perform and interpret transoral ultrasound of the palatine and lingual tonsils in patients with suspected oropharyngeal cancer. This technique offers a reliable adjunct to conventional assessment but requires substantial operator experience and patient cooperation.
Amalie P. Posselt   +2 more
wiley   +1 more source

Outcomes of the Paramedian Forehead Flap for Nasal Reconstruction: Systematic Review and Meta‐Analysis

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objective(s) Paramedian forehead flap (PMFF) reconstruction remains the gold standard for complex nasal defects, yet outcomes have not been comprehensively synthesized. We aimed to define flap survival, complication profiles, and reconstructive patterns through the largest systematic review and meta‐analysis of PMFFs to date.
Renate Ma   +4 more
wiley   +1 more source

Laryngeal Cancer Microbiome Study Reveals Parvimonas and Campylobacter as Potential Therapy Targets

open access: yesThe Laryngoscope, EarlyView.
In this prospective study, we compared the laryngeal microbiomes of 24 treatment‐naïve laryngeal cancer patients to 33 controls using 16S rRNA sequencing. Laryngeal cancer samples demonstrated significant microbial community changes, with enrichment of Parvimonas and Campylobacter, alongside Cotton–Meyer stage‐associated increases in potentially ...
Hetal Lad   +15 more
wiley   +1 more source

Efficacy of Intratympanic Sodium Thiosulfate Gel Injection to Prevent Cisplatin‐Induced Ototoxicity

open access: yesThe Laryngoscope, EarlyView.
This randomized controlled trial included 28 patients with head and neck cancer receiving cisplatin chemotherapy, with intratympanic sodium thiosulfate gel administered to one ear and the contralateral ear serving as control. Based on ASHA criteria, the incidence of ototoxicity did not differ significantly between treated and control ears.
Kunyakorn Vittayakoonsakulchai   +7 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág   +5 more
wiley   +1 more source

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