Results 251 to 260 of about 141,551 (313)

Multifunctional Nanodiamond Conjugate With a Tumor‐Specific EGFR‐Targeting Peptide and Photoactivated CO Release for Improved Therapeutic Efficacy in Head and Neck Cancers

open access: yesSmall, EarlyView.
A multifunctional nanodiamond conjugate carrying a blue light‐activated carbon monoxide‐releasing molecule and an EGFR‐targeting peptide enables efficient, targeted CO delivery in vitro and in vivo. Upon photoactivation, the particles induce cancer‐specific cytotoxicity and significantly suppress tumor growth and lymph node metastasis in a head and ...
Harsh Nitin Dongre   +12 more
wiley   +1 more source

Clinical Features and Outcomes of Chronic Otitis Media Complications: A 20‐Year Retrospective Study at a Tertiary Hospital

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Chronic otitis media (COM) is a major public health concern, particularly in developing countries. Although complications have decreased with modern antibiotics, they still cause significant morbidity and mortality. This study analyzed the clinical features, bacteriological profiles, and treatment outcomes of COM complications at a ...
Viraporn Atchariyasathian   +1 more
wiley   +1 more source

Outcomes in Orbit‐Sparing Versus Orbit‐Sacrificing Surgery for Sinonasal Malignancies With Orbital Involvement: A Systematic Review and Meta‐Analysis

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Sinonasal malignancies with orbital involvement may be managed with orbit‐sacrificing or orbit‐preserving surgical approaches, with a recent shift towards orbital preservation to reduce postoperative morbidity while maintaining oncological success.
Claire Jing‐Wen Tan   +9 more
wiley   +1 more source

Facility Type Predicts Treatment Regimen for Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Treatment landscapes are changing for HPV+ oropharyngeal cancer (OPC) without compromising oncologic outcomes. We aim to analyze treatment trends of HPV+ OPC at academic (ACs) and nonacademic centers (NACs). Methods The National Cancer Database was queried, and multinomial logistic regression was used to predict treatment trends ...
Monica S. Trent   +4 more
wiley   +1 more source

Plasma Proteomics Analysis Identifying IGFBP2 as a Potential Diagnostic Biomarker for Laryngeal Squamous Cell Carcinoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Currently, there are no blood biomarkers available for the early diagnosis of laryngeal squamous cell carcinoma (LSCC). The objective of this study was to search for potential plasma biomarkers for the diagnosis of LSCC. Methods Plasma samples were taken from patients with LSCC and healthy controls for proteomic analysis.
Shuang Teng   +13 more
wiley   +1 more source

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