Results 51 to 60 of about 2,257 (201)
Carbon‐Supported Catalytic Systems Assembled by π–π Interactions
This review explores the noncovalent immobilization of organic and organometallic catalysts on carbonaceous supports through π–π interactions, highlighting its potential to enhance catalyst recovery, recyclability, and the sustainability of organic synthesis.
Chloé Jamalkhan +8 more
wiley +1 more source
A Squaramide-Based Organocatalyst as a Novel Versatile Chiral Solvating Agent for Carboxylic Acids
A squaramide-based organocatalyst for asymmetric Michael reactions has been tested as a chiral solvating agent (CSA) for 26 carboxylic acids and camphorsulfonic acid, encompassing amino acid derivatives, mandelic acid, as well as some of its analogs ...
Fabio Spiaggia +5 more
doaj +1 more source
In this work, we describe the Michael addition–cyclization reaction of 2-(2-nitrovinyl)phenol with two different reactive Michael donors, which lead to chiral benzopyran derivatives.
Eva Veverková +2 more
doaj +1 more source
Selective N‐Functionalization of Pyrazoles
This review traces the evolution of regioselective N‐functionalization strategies for pyrazoles, a key class of nitrogen heterocycles widely used in medicinal chemistry. Due to rapid tautomerism, N‐functionalization often lacks selectivity, leading to poor and unpredictable regioisomeric outcomes.
Lucas Popek +2 more
wiley +1 more source
Aromatic β-sheet foldamers based on tertiary squaramides [PDF]
Suitably substituted aryl-methyl tertiary squaramides are convenient and efficient at promoting hairpin turns in aromatic amide sequences.
Joan Atcher +5 more
openaire +2 more sources
This computational study reveals mechanistic origins of activator‐free gold catalysis in HFIP, showing hydrogen‐bond‐assisted activation rather than chloride abstraction. Turnover‐limiting transition states govern activity, strongly modulated by ligand sterics and electronics, while gold uniquely outperforms silver and copper analogues systems ...
Michele Tomasini +2 more
wiley +1 more source
Simple squaramide receptors for highly efficient anion binding in aqueous media and transmembrane transport [PDF]
A family of acyclic squaramide receptors (L1-L5) have been synthesised with the aim to bind anions in a competitive solvent mixture and to evaluate how the presence of additional H-bond donor groups on the squaramide scaffold could affect the affinity ...
Lippolis V. +9 more
core +1 more source
In this paper, the organocatalytic asymmetric Michael addition/hemiketalization cascade reactions between hydroxymaleimides and 2-hydroxynitrostyrenes were developed, which provided a new protocol for building a chiral ring-fused chroman skeleton.
Dong-Hua Xie, Cheng Niu, Da-Ming Du
doaj +1 more source
A Multi‐Scale Computational Framework for Anti‐Persister Tuberculosis Drug Discovery
This review presents an integrated QSAR–scaffold design–docking–MD framework for discovering anti‐persister tuberculosis agents active in dormant granuloma‐like conditions. By targeting Mtb bioenergetics and prioritising dual NDH‐2/cytochrome bd oxidase inhibition, the workflow advances rational design of candidates with higher resistance barriers ...
Said Moshawih +6 more
wiley +1 more source
Squaramide Equilibrium Acidities in DMSO
A number of popular squaramide organocatalysts’ acidities were determined by an overlapping indicator method in DMSO via UV spectrophotometric titrations. The pKa values are in the range of 8.37–16.46.
Xin Li (51274) +3 more
core +1 more source

