Results 61 to 70 of about 2,989 (293)
Photophysical Characterization and BSA Interaction of Direct Ring Carboxy Functionalized Symmetrical squaraine Dyes [PDF]
, 2017 A series of far-red sensitive symmetrical squaraine dyes bearing direct –COOH functionalized indole ring were synthesized, characterized and subjected to photophysical investigations.
Hayase Shuzi +3 more
core +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Condensed Matter Physics, 2021 Using the previously developed model we explore the processes of polarization rotation in antiferroelectric crystals of squaric acid by the electric fields directed arbitrarily within the ac plane.
A. P. Moina
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
3-Chloro-4-(5-methoxy-1H-indol-3-yl)cyclobut-3-ene-1,2-dione
Molbank, 2013 The indole ring system is a prominent partial structure of several protein kinase inhibitor families. The title compound is the first example of a 5-substituted indolyl squaryl chloride with free indole nitrogen.
Johann Grünefeld +7 more
doaj +1 more source
Sodium hydroxide pretreatment as an effective approach to reduce the dye/holes recombination reaction in P-Type DSCs [PDF]
, 2019 We report the synthesis of a novel squaraine dye (VG21-C12) and investigate its behavior as p-type sensitizer for p-type Dye-Sensitized Solar Cells.
Barbero, Nadia +5 more
core +2 more sources
Molecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Case report: Dupilumab therapy for alopecia areata in a 4-year-old patient resistant to baricitinib
Frontiers in Medicine, 2023 Alopecia areata (AA) is a non-scarring hair loss disorder. Alopecia totalis (AT) and alopecia universalis (AU) are the severe subtypes of AA. Age of onset before 6 years of age, disease duration of more than 1 year, and extensive alopecia involving more ...
Lu Cai +7 more
doaj +1 more source
Investigation of squaric acid derivates
Polymer Testing, 2001 Abstract The aims of the present work are to prove the possibility of employing IR spectra to investigate the compounds obtained by interaction of Squaric acid (H2Sq) and phenyl- or alkyl glycidyl ethers (PhGE or AlkGE), to establish the most suitable absorbances for quantitative analyses and to evaluate the formation of H-bonds. Indication of H-bond
Z Glavcheva, Ts Kolev, I Glavchev
openaire +1 more source