Results 71 to 80 of about 2,989 (293)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Polymeric Terbium(III) Squarate Hydrate as a Luminescent Magnet
Crystals, 2021 Polymeric terbium(III) squarate hydrate [{Tb2(C4O4)3(H2O)8}n] was prepared from TbCl3 or Tb2O3 and squaric acid. The crystal structure was determined in a monoclinic Pc space group, and the whole molecular arrangement gives a sandwiched two-dimensional ...
Rina Takano, Takayuki Ishida
doaj +1 more source
X-ray structures of dinuclear copper(I) and polynuclear copper(II) complexes with the 2,4-bis(cyanamido)cyclobutane-1,3-dione dianion [PDF]
, 2006 From the 2,4-bis(cyanamido)cyclobutane-1,3-dione dianion (2,4-NCNsq2−), two copper complexes [Cu2(PPh3)4(PhCN)2(μ-2,4-NCNsq)] · PhCN (1) and [Cu(dien)(μ-2,4-NCNsq) · H2O]n (2) have been synthesized and characterized by IR and electronic absorption ...
Cortadellas, Olivier +4 more
core +2 more sources
Molecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Aminosquaraines as potential photodynamic agents: Synthesis and evaluation of in vitro cytotoxicity [PDF]
, 2017 © 2017 Elsevier Ltd The synthesis of several aminosquaraine cationic dyes displaying strong absorption within the so-called phototherapeutic window (650–850 nm) is described.
Calhelha, Ricardo C. +4 more
core +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Development of easy-use cortisol detector: DTNB, blue squaric dye, and choline oxidase sensitivity to acetylcholinesterase [abstract] [PDF]
, 2006 Faculty Mentor: Dr. Mark Milanick, Medical Pharmocology & PhysiologyAbstract only availableCortisol, an adrenal hormone released during stressful "fight or flight" situations increases blood glucose levels but also affects other physiological systems of ...
Campbell, Claire
core
Intramolecular Imino Diels-Alder Reaction: Progress toward the Synthesis of Uncialamycin [PDF]
, 2009 We herein described an intramolecular imino Diels-Alder reaction promoted with BF3.OEt2/DDQ affording substituted quinolines. Using this procedure, we prepared the chiral quitioline moiety of the uncialamycin, a new enediyne natural ...
Desrat, S, van de Weghe, P
core +3 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Retrospective review of diphencyprone in the treatment of alopecia areata [PDF]
, 2015 Contact immunotherapy with diphencyprone (DCP) is used to treat alopecia areata (AA). Its reported efficacy is variable, and individual response cannot be predicted.
Holmes, S., Lamb, R. C., Young, D.
core +1 more source