Results 141 to 150 of about 895,142 (270)

Vacancy defect‐induced electron homing breaks phosphodiester bonds for RNA depletion‐driven cancer therapy

BMEMat, EarlyView.
Illustration of 5% S‐vacancy Bi2S3 mediated phosphodiester bonds cleavage in RNA of hepatocellular carcinoma cells, which suppressing ERI3 expression, inhibiting cell proliferation and promoting apoptosis. Abstract Genome‐wide hypertranscription is a hallmark of malignant progression.
Chuncheng Yang, Zehao Shen, Guangming Xiang, Zhe Liu, Huaxin Liu, Jiabei Li, Ao Wang, Yelin Wu, Peiran Zhao, Xingwu Jiang, Jinghan Wang, Xiaoqing Jiang, Wenbo Bu   +12 more
wiley   +1 more source

Macrophage SR-BI modulates autophagy via VPS34 complex and PPARα transcription of Tfeb in atherosclerosis. [PDF]

J Clin Invest, 2021
Tao H, Yancey PG, Blakemore JL, Zhang Y, Ding L, Jerome WG, Brown JD, Vickers KC, Linton MF.   +8 more
europepmc   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

High Density Lipoprotein Reduces Blood Pressure and Protects Spontaneously Hypertensive Rats Against Myocardial Ischemia-Reperfusion Injury in an SR-BI Dependent Manner. [PDF]

Front Cardiovasc Med, 2022
Al-Jarallah A, Babiker F.
europepmc   +1 more source

Effects of restoring SR-BI expression in BM derived cells on plasma levels of TNFα and IL-6 in HFCC diet fed SR-BI-null/apoE-hypomorphic mice.

, 2013
A. TNFα and B. IL-6 levels in plasma from control SR-BI−/− → SR-BI−/− (white bars) and SR-BI+/+ → SR-BI−/− mice (black bars) after 3 weeks of HFCC diet feeding. Shown are mean levels for n = 8 mice per group. Error bars correspond to standard errors.
Mark T. Fuller (445277), Pei Yu (203358), Suleiman A. Igdoura (445280), Bernardo L. Trigatti (445281), Elizabeth J. White (445279), Dina Aboutouk (445276), Ying Pei (445275), Xing Chen (140292), Omid Dadoo (445278)   +8 more
core   +1 more source

Mitochondria‐endoplasmic reticulum organelle glue as maturation promoter for origination/dimensional dual‐cross cardiomyocytes

BMEMat, EarlyView.
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang, Hao Sun, Chenqi Duan, Jiajia Chang, Yuxing Wang, Ming Zhao, Huiyue Zhao, Shan Lu, Yang Yang, Da Huo   +9 more
wiley   +1 more source

Samhandling i samferdselsprosjekter [PDF]

, 2017
Denne rapporten presenterer resultater fra forskningsprosjektet «Samhandling i samferdselsprosjekter», som ble utført ved Senter for byggenæringen ved Handelshøyskolen BI fra september 2013 til desember 2016. Prosjektet har vært finansiert av partnerne i
Swärd, Anna
core  

Resource‐Centered Transformation Paths: The Role of Digital Transformation in Optimizing SME Resources for Sustainable Entrepreneurship

Business Strategy and the Environment, EarlyView.
ABSTRACT The critical role of small and medium‐sized enterprises (SMEs) in driving economic growth through employment generation and innovation cannot go unseen, especially the efforts of small firms in promoting sustainable entrepreneurship. With more market and consumer focus on sustainability and the shift toward eco‐friendly products, SMEs can ...
Nasser Hadi Alajmi
wiley   +1 more source

High Entropy–Driven Performance Enhancement in Perovskite Oxides for Energy Conversion and Storage Systems

Carbon Energy, EarlyView.
High‐entropy perovskite oxides enable tunable structures and properties through multi‐cation disorder and entropy stabilization. This review summarizes advances in synthesis, structural and defect engineering, and their applications in OER/ORR, CO2RR, and electrochemical energy storage, highlighting in situ characterization and modeling that clarify ...
Obeylaw Moyo, Jiaqiao Yang, Mingzhuang Liang, Hyunseung Kim, Wei Wang, Yong Beom Kim, Junxiong Zhang, WooChul Jung, Hainan Sun   +8 more
wiley   +1 more source

Thiosemicarbazone Copper Chelator BLT-1 Blocks Apicomplexan Parasite Replication by Selective Inhibition of Scavenger Receptor B Type 1 (SR-BI). [PDF]

Microorganisms, 2021
Larrazabal C, López-Osorio S, Velásquez ZD, Hermosilla C, Taubert A, Silva LMR.   +5 more
europepmc   +1 more source