Results 271 to 280 of about 1,036,062 (294)

The HDL Receptor SR-BI

2010
Scavenger receptor class B type I (SR-BI) was the first molecularly well-defined and functionally active cell surface HDL receptor to be described. SR-BI mediates the transfer of cholesterol from HDL to cells via a mechanism called selective lipid uptake. In vitro and in vivo studies have established that SR-BI is a physiologically relevant lipoprotein
Attilio Rigotti, Monty Krieger
openaire   +1 more source

Influence of the HDL receptor SR-BI on atherosclerosis

Current Opinion in Lipidology, 1999
The scavenger receptor class B, type I (SR-BI) is an HDL receptor that mediates selective cholesterol uptake from HDL to cells. In rodents, SR-BI has a critical influence on plasma HDL-cholesterol concentration and structure, the delivery of cholesterol to steroidogenic tissues, female fertility, and biliary cholesterol concentration.
M, Krieger, K, Kozarsky
openaire   +2 more sources

The Janus-faced role of SR-BI in atherosclerosis

Nature Metabolism, 2019
The entry of remnants of cholesterol-rich lipoproteins, such as low-density lipoprotein (LDL), from the blood stream into the intima of large arteries initiates and then perpetuates atherosclerosis. A study published in Nature sheds new light on this important process by identifying scavenger receptor BI (SR-BI) as a major receptor that mediates LDL ...
Xinbo Zhang, Carlos Fernández-Hernando
openaire   +2 more sources

SR-BI Mediates Cholesterol Efflux via Its Interactions with Lipid-Bound ApoE. Structural Mutations in SR-BI Diminish Cholesterol Efflux

Biochemistry, 2005
Apolipoprotein E (apoE) and the lipoprotein receptor SR-BI play critical roles in lipid and lipoprotein metabolism. We have examined the cholesterol efflux from wild-type (WT) and mutant forms of SR-BI expressed in ldlA-7 cells using reconstituted discoidal particles consisting of apoE, 1-palmitoyl-2-oleoyl-l-phospatidylcholine (POPC), and cholesterol (
Angeliki, Chroni, Thomas J F, Nieland, Kyriakos E, Kypreos, Monty, Krieger, Vassilis I, Zannis   +4 more
openaire   +2 more sources

Resistivity of liquid SrBi and SrSb alloys

Journal of Non-Crystalline Solids, 1993
Abstract Recently, measurements of the electrical resistivity, ϱ, of the liquid SrBi and SrSb systems have been performed as a function of temperature for the entire concentration range. A very high and sharp resistivity maximum occurs at 60 at.% Sr for both systems, indicating that the mixture is semiconducting at this composition. Comparison with
R Xu, W van der Lugt
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Incommensurate ordering in Ca-Sr-Bi-Cu oxide superconductors

Proceedings, annual meeting, Electron Microscopy Society of America, 1988
High temperature superconductivity in non-rare earth ceramic oxides has been recently reported, however the structure and composition of the phase(s) has yet to be unequivocally identified. In the Ca-Sr-Bi-Cu Oxide system onset transition temperatures as high as 120 K have been reported, in both single and multiphase specimens.
N. J. Zaluzec, D. G. Hinks, D. W. Capone, D. Shi, L. Soderholm, B. Dabrowski, J. Z. Liu, J. W. Downey, D. J. Lam   +8 more
openaire   +1 more source

Abstract 546: SR-BI Functions on Plasma HDL Homeostasis -low Plasma preβHDL Level in SR-BI Null Mice by 2D PAGE Analysis

Arteriosclerosis, Thrombosis, and Vascular Biology, 2015
ApoA-I-ABCA1 mediated HDL synthesis is major source of plasma preβHDL generation. Lipid free apoA-I is mainly provided from newly synthesized from liver, small intestinal cells and the other hand, apoA-I is also provided from deflated HDL result of transferring cholesterylester into target cells via SR-BI.
Maki Tsujita, Tomo Yokota, Nobukatsu Akita, Yasutaka Maekawa, Junki Yamamoto, Alan T Remaley, Shinji Yokoyama   +6 more
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Role of SR-BI in regulating lipoprotein structure and metabolism

Drug News & Perspectives, 2001
The scavenger receptor class B type I (SR-BI) is a cell surface lipoprotein receptor that mediates physiologically relevant selective cholesteryl ester uptake from high-density lipoprotein (HDL). SR-BI appears to be required for the maintenance of reverse cholesterol transport, normal HDL levels and HDL structure by means of hepatic-selective HDL ...
openaire   +2 more sources

Population-based study of SR-BI genetic variation and lipid profile

Atherosclerosis, 2004
The variability of the Class B Type I Scavenger Receptor (SR-BI) gene in human populations and the relation of its variants to blood lipids was investigated in a random sample of 1756 untreated adult residents of Geneva, Switzerland, during 1999-2000.
Alfredo, Morabia, Barbara M, Ross, Michael C, Costanza, Eftihia, Cayanis, Maria Sol, Flaherty, Gabriela B, Alvin, Kamna, Das, Richard, James, An-Suei, Yang, Oleg, Evagrafov, T Conrad, Gilliam   +10 more
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New oxide superconductors in the Sr-Bi-Cu-O system

Journal of Materials Science, 1989
New oxide superconductors in the Sr-Bi-Cu-O system were prepared by the conventional processing techniques consisting of mixing, pressing and sintering. The compositions of the superconductors are located in a range surrounded by CuO, SrCu2O3 and Sr0.9Bi1.1O2.55.
Keiji Moroishi, Akihisa Inoue, Kunio Matsuzaki, Tsuyoshi Masumoto   +3 more
openaire   +1 more source