Results 111 to 120 of about 512,141 (378)

Preclinical Evaluation of 68Ga-labeled RGD Peptide for Detection of Malignant Angiogenesis

open access: yesРазработка и регистрация лекарственных средств, 2020
Introduction. The early detection of tumor growth remains one of the most important tasks of diagnostic nuclear medicine. The vascular growth being created malignant neoplasms is a good target for the purpose.
O. E. Klementyeva   +5 more
doaj   +1 more source

c-Src inhibition improves cardiovascular function but not remodeling or fibrosis in Ang II-induced hypertension [PDF]

open access: yes, 2016
c-Src plays an important role in angiotensin II (Ang II) signaling. Whether this member of the Src family kinases is involved in the development of Ang II–induced hypertension and associated cardiovascular damage in vivo remains unknown. Here, we studied
Antunes, Tayze T.   +6 more
core   +1 more source

Visualizing the mechanical activation of Src [PDF]

open access: yesNature, 2005
The mechanical environment crucially influences many cell functions. However, it remains largely mysterious how mechanical stimuli are transmitted into biochemical signals. Src is known to regulate the integrin-cytoskeleton interaction, which is essential for the transduction of mechanical stimuli.
Wang, Yingxiao   +6 more
openaire   +5 more sources

Large Spin‐Orbit Torque with Multi‐Directional Spin Components in Ni4W

open access: yesAdvanced Materials, EarlyView.
Ni4W is theoretically proposed and experimentally verified as a promising unconventional spin‐orbit torque (SOT) material for generating multi‐directional spins. Epitaxial Ni4W thin films with outstanding crystallinity are grown by magnetron sputtering.
Yifei Yang   +17 more
wiley   +1 more source

MicroRNA-7641 is a regulator of ribosomal proteins and a promising targeting factor to improve the efficacy of cancer therapy

open access: yesScientific Reports, 2017
Many diseases, including myocardial infarction, autoimmune disease, viral diseases, neurodegenerative diseases, and cancers, are frequently diagnosed with aberrant expression of microRNAs (miRNAs) and their allied pathways.
Abu Musa Md. Talimur Reza   +5 more
doaj   +1 more source

The nuclear contacts and short range correlations in nuclei

open access: yes, 2018
Atomic nuclei are complex strongly interacting systems and their exact theoretical description is a long-standing challenge. An approximate description of nuclei can be achieved by separating its short and long range structure.
Barnea, N.   +5 more
core   +2 more sources

Synapsin Phosphorylation by Src Tyrosine Kinase Enhances Src Activity in Synaptic Vesicles [PDF]

open access: yesJournal of Biological Chemistry, 2007
Synapsins are synaptic vesicle-associated phosphoproteins implicated in the regulation of neurotransmitter release. Synapsin I is the major binding protein for the SH3 domain of the kinase c-Src in synaptic vesicles. Its binding leads to stimulation of synaptic vesicle-associated c-Src activity.
ONOFRI, FRANCO   +7 more
openaire   +5 more sources

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

open access: yesAdvanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang   +3 more
wiley   +1 more source

Mechanisms for redox-regulation of protein kinase C

open access: yesFrontiers in Pharmacology, 2015
Protein kinase C (PKC) is comprised of a family of signal-regulated enzymes that play pleiotropic roles in the control of many physiological and pathological responses.
Susan F. Steinberg
doaj   +1 more source

Development of Radiopharmaceutical Composition for Radionuclide Diagnostics of Malignant Melanoma

open access: yesРазработка и регистрация лекарственных средств, 2020
Introduction. Skin cancers came first in Russia in numbers of oncological diseases. Melanoma, making up only a small part of these cases, leads to the most serious consequences.
O. E. Klementyeva   +6 more
doaj   +1 more source

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