Results 131 to 140 of about 153,822 (251)

A prospective natural history study protocol for clinical trial readiness in synaptic disorders

open access: yesEpilepsia, EarlyView.
Abstract Objective STXBP1‐related disorder (STXBP1‐RD) and SYNGAP1‐related disorder (SYNGAP1‐RD) are two common genetic synaptopathies that are associated with epilepsy, developmental delay, intellectual developmental disorder, and behavioral problems.
Jillian L. McKee   +38 more
wiley   +1 more source

Empirical Model of Post‐Earthquake Restoration Time for Building Components Based on Data From the 2022 Fukushima‐ken Oki Earthquake in Japan

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Estimation of the time required for damaged building components to return to their pre‐earthquake conditions through repair is a critical element in assessing the seismic resilience of buildings, and it requires consideration of uncertainty.
Tomoaki Nishino   +5 more
wiley   +1 more source

Non-receptor tyrosine kinase signaling pathways and therapeutic implications. [PDF]

open access: yesSignal Transduct Target Ther
Hossain MDA   +4 more
europepmc   +1 more source

A cross‐sectional study of caesarean deliveries performed by medical doctors and associate clinicians in nine district and regional hospitals in Sierra Leone using the Robson Ten Group Classification System

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Maternal and neonatal mortality remain high in Sierra Leone despite significant decline in the last decade. The aim of the present study was to evaluate obstetric care delivery using the Robson Ten Group Classification System (TGCS), focusing on caesarean delivery (CD) and task‐sharing.
Josien Westendorp   +10 more
wiley   +1 more source

Regulatory Effects of Ammonium Chloride in an In Vitro Model of Hepatic Encephalopathy: Mechanisms Involving ACTA2‐Mediated Cytoskeletal Remodeling

open access: yesiLABMED, EarlyView.
Hyperammonemic stress suppresses ACTA2 expression and induces F‐actin cytoskeletal remodeling in astrocytes. The resulting inhibition of FAK/c‐Src signaling contributes to apoptosis, G2/M arrest, AQP4‐mediated swelling and junction‐associated proteins dysregulation, revealing a central role for ACTA2‐dependent cytoskeletal dysfunction in hepatic ...
Yue Tang   +6 more
wiley   +1 more source

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