Results 111 to 120 of about 260,978 (272)

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

SSeCKS/Gravin/AKAP12 attenuates expression of proliferative and angiogenic genes during suppression of v-Src-induced oncogenesis-0

, 2011
Copyright information:Taken from "SSeCKS/Gravin/AKAP12 attenuates expression of proliferative and angiogenic genes during suppression of v-Src-induced oncogenesis"BMC Cancer 2006;6():105-105.Published online 25 Apr 2006PMCID:PMC1463002.Copyright © 2006 ...
Lingqiu Gao (72786), Irwin H Gelman (72787), Yongzhong Liu (72785)   +2 more
core   +1 more source

Force‐Electric Nanotentacles of Tantalum Implant Accelerate Cellular Energy Metabolism/Crosstalk for Immunomodulation‐Vascularized Bone Integration

Advanced Science, EarlyView.
A biomimetic force‐electric nanotentacle‐enabled tantalum (Ta) implant with surface‐nanostructured LiTaO3 (n‐LiTaO3) was first developed via laser nanofabrication combined with Li+‐induced in situ reaction, enabling the transduction of ultrasound into bioelectrical cues.
Taixing Zhang, Ke Ma, Kangqing Zuo, Pandong Lin, Tailong Zhang, Rongliang Ding, Linbo Zhang, Aonan Li, Yinchuan Wang, Yanling Huang, Jichao Feng, Guiyong Xiao, Yupeng Lu, Bing Han, Zhiqiang Wang, Ningbo Li   +15 more
wiley   +1 more source

The Shuilian Cave in the Upper Region of the Chang River (Karst of NW Yunnan, China)

Acta Carsologica, 2009
In upper reaches of the Chang (Yangtze) river, in Deqen prefecture, in northwestern part of the Yunnan province, karst is developed in Devonian carbonate rocks.
Martin Knez, Janja Kogovšek, Andrej Kranjc, Hong Liu, Metka Petrič, Tadej Slabe   +5 more
doaj   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

Advanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao, Yuechen Han, Jie Li, Peng Luo, Lin Qi, Zhiwei Xia, Xiaosong Li, Quan Cheng, Chenshen Huang, Wantao Wu, Hao Zhang   +10 more
wiley   +1 more source

A map of community‐based obesity prevention initiatives in Australia following obesity funding 2009–2013

Australian and New Zealand Journal of Public Health, 2015
Objective: Obesity is the single biggest public health threat to developed and developing economies. In concert with healthy public policy, multi‐strategy, multi‐level community‐based initiatives appear promising in preventing obesity, with several ...
Jillian Whelan, Penny Love, Anne Romanus, Tahna Pettman, Kristy Bolton, Erin Smith, Tim Gill, John Coveney, Elizabeth Waters, Steve Allender   +9 more
doaj   +1 more source

SRC-3/AIB1 protein and gene amplification levels in human esophageal squamous cell carcinomas

, 2007
It has been suggested that the steroid receptor coactivatior-3 (SRC-3) gene, also known as AIB1, ACTR, RAC3, p/CIP and TRAM-1, located at 20q12, plays an oncogenic role in several types of human cancers.
Lv, ZL, Zeng, YX, Xu, FP, Guan, XY, Wu, HX, Xie, D, Liu, YD, Wen, JM, Bi, J   +8 more
core   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2

Advanced Science, EarlyView.
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang, Chuanzan Zhou, Jiaoyan He, Pengpeng Huang, Rong Zhang, Huan Hu, Meng Jiao, Linyi Hu, Feng Liu, Xiaolong Qi, Xiang He, Yunkai Yang, Y Eugene Chinn, Dechao Feng, Dahong Zhang, Qi Zhang   +15 more
wiley   +1 more source

ING1 binds to Src and Src mutants.

, 2013
A) Wild-type Src and the mutants indicated were ectopically expressed in HEK293 cells. Expression levels of Src and ING1 are shown in immunoblots of whole cell extracts (upper two panels).
Keiko Suzuki (216606), Lisa Yu (245028), Rebecca YY. Leong-Quong (400788), Jeffrey D. Bjorge (352679), Satbir Thakur (141395), Donald J. Fujita (352685), Karl Riabowol (141426), Andy Pang (400789)   +7 more
core   +1 more source