Results 111 to 120 of about 242,192 (301)
Cell Shape, Src location, and total Src.
, 2013 (A) MDA-MB-231 cells transfected with GFP-tagged constitutively active Src exert tended to have a higher surface area to volume ratio ...
Daniel Koch (388049) +8 more
core +1 more source
Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function
Advanced Science, EarlyView.This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang +10 more
wiley +1 more source
Experimental Study on Elastic-Plastic Behavior of SRC Columns with High Strength Steel
, 2005 P(論文)The demand to use high strength and high performance material because of large span and high rise of building in recent years. As to use of high-strength steel in composite steel and reinforced concrete structures, it remains to be clarified whether
44159 +11 more
core
ING1 binds to Src and Src mutants.
, 2013 A) Wild-type Src and the mutants indicated were ectopically expressed in HEK293 cells. Expression levels of Src and ING1 are shown in immunoblots of whole cell extracts (upper two panels).
Keiko Suzuki (216606) +7 more
core +1 more source
Advanced Science, EarlyView.Compared to a healthy random nanofibrous fibronectin microenvironment, a fibrotic aligned nanofibrous fibronectin microenvironment employs a specific integrin, α5β1 integrin, to activate early pro‐fibrotic fibroblast behaviors and later fibrotic fibroblast tissue formation with cell/F‐actin alignment, α‐SMA expression, and cell‐driven aligned ...
Doğuhan Beyatlı +3 more
wiley +1 more source
Protein levels of Src in GFP-Src transfectants.
, 2013 Lysates from clones of GFP-Src transfectants (30 µg each) were compared by immunoblotting using anti-GFP (α-GFP), anti-Src (α-Src), anti-pSrc418 (α-pSrc418), and anti-actin (α-actin).
Daniel Koch (388049) +8 more
core +1 more source
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
Advanced Science, EarlyView.This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer.
, 2017 Hepatocellular carcinoma (HCC) is the fifth most common solid tumor in the world and the third leading cause of cancer-associated deaths. A Sleeping Beauty-mediated transposon mutagenesis screen previously identified mutations that cooperate with MYC to ...
Chao Xing +19 more
core +1 more source
Advanced Science, EarlyView.This work overcomes the long‐standing challenge of hydrophilic modification of silicone rubber via a gradient polarity modification strategy. By constructing a hydrophilic interpenetrating network within cured SR, simultaneous surface‐to‐bulk modification is achieved while enabling monitoring through a Eu3+ complex fluorescent tracer.
Lihui Zhang +11 more
wiley +1 more source
Advanced Science, EarlyView.Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole +17 more
wiley +1 more source