Results 91 to 100 of about 260,978 (272)
The expression of p-c-src-Y419 and SDCBP in triple-negative breast cancer tissue (×200).
, 2017 Case 1 has weak p-c-src-Y419 and negative SDCBP expression, Case 2 has weak p-c-src-Y419 and weak SDCBP expression, Case 3 has moderate p-c-src Y419 and moderate SDCBP expression, and Case 4 has strong p-c-src-Y419 and strong SDCBP expression.
Jun Zhang (48506) +9 more
core +1 more source
Advanced Science, EarlyView.This study elucidates the phase transition pathway of surface‐engineered perovskite films. During spin‐coating, n = 1 2D perovskite dominantly forms, while subsequent annealing drives OA+ release and induces conversion to higher n‐value 2D phases.
Yajie Yang +12 more
wiley +1 more source
Phosphorylation of Unique domains of Src family kinases
Frontiers in Genetics, 2014 Members of the Src family of kinases (SFKs) are non-receptor tyrosine kinases involved innumerous signal transduction pathways. The catalytic, SH3 and SH2 domains are attached tothe membrane-anchoring SH4 domain through the intrinsically disordered ...
Irene eAmata +3 more
doaj +1 more source
Nuclear expression of PG-21, SRC-1, and pCREB in regions of the lumbosacral spinal cord involved in pelvic innervation in young adult and aged rats [PDF]
, 2012 In rats, ageing results in dysfunctional patterns of micturition and diminished sexual reflexes that may reflect degenerative changes within spinal circuitry.
Ranson, R. N. +7 more
core +1 more source
Advanced Science, EarlyView.Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi +7 more
wiley +1 more source
Advanced Science, EarlyView.VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu +13 more
wiley +1 more source
Cancer Cell, 2009 In this issue of Cancer Cell, Lowy and colleagues show that the SH2 domain of tensin-3 is regulated by phosphorylation by Src and that this phosphorylation promotes the oncogenic function of tensin-3. Phosphorylation of the SH2 domain represents a novel mechanism for the regulation of SH2 ligand binding.
openaire +2 more sources
Neural Regeneration ResearchPreliminary studies on emerging herbal ingredients have highlighted alternative pathways that inflammation and modulate perturbed immunity as valuable strategies for treating depression.
Wenqian Zhu, Bingjin Li, Ranji Cui
doaj +1 more source
BMC Health Services Research, 2020 Background Management of Life-threatening Emergency (LTE) patients in urban and rural areas is an important challenge, which can affect pre-hospital mortality rate.
Homayoun Sadeghi-Bazargani +4 more
doaj +1 more source
, 2017 Syndecan-binding protein (SDCBP) and tyrosine-419 phosphorylated c-src (p-c-src-Y419) expression and the pathological features of triple-negative breast cancers.
Jun Zhang (48506) +9 more
core +1 more source