Results 71 to 80 of about 242,192 (301)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Significant association of SRC protein expression with the progression, recurrence, and prognosis of oral squamous cell carcinoma in Taiwan

open access: yes, 2014
Background Src protein overexpression correlates with progression and prognosis of a variety of human cancers. Methods This study used immunohistochemistry to examine the expression of Src protein in 93 specimens of oral squamous cell carcinoma (OSCC ...
Cheng, Shih-Jung;Kok, Sang-Heng;Lee, Jang-Jaer;Kuo, Mark Yen-Ping;Cheng, Shih-Lung;Huang, Ying-Luo;Chen, Hsin-Ming;Chang, Hao-Hueng;Chiang, Chun-Pin   +1 more
core   +1 more source

Laboratory diagnosis of nonpolio enteroviruses: A review of the current literature

open access: yesBiosafety and Health, 2023
Infections by nonpolio enteroviruses (EVs) are highly prevalent, particularly among children and neonates, where they may cause substantial morbidity and mortality.
Tarek Itani   +3 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

De novo variant in tyrosine kinase SRC causes thrombocytopenia: case report of a second family

open access: yesPlatelets, 2019
A germline heterozygous gain-of-function p.E527K variant in tyrosine kinase SRC was previously found to cause thrombocytopenia, myelofibrosis, bleeding, bone pathologies, premature edentulism and mild facial dysmorphia in nine patients of a single ...
Lore De Kock   +6 more
doaj   +1 more source

Water temperature as a natural tracer – a case study of the Malenščica karst spring (SW Slovenia)

open access: yesGeologia Croatica, 2010
For the adequate protection of karst springs it is important to understand the functioning of karst systems in their recharge areas. Besides tracer tests with artificial tracers, tracings with natural tracers, such as temperature, are a very useful ...
Metka Petrič, Janja Kogovšek
doaj   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin   +14 more
wiley   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study from the EUSTAR Cohort

open access: yesArthritis Care &Research, Accepted Article.
Objective JAK inhibitors (JAKis) have shown promising effects in early‐phase studies of SSc. We aimed to assess the safety and explore effectiveness of JAKis compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the EUSTAR cohort was performed.
Stefano Di Donato   +27 more
wiley   +1 more source

Mechanisms for redox-regulation of protein kinase C

open access: yesFrontiers in Pharmacology, 2015
Protein kinase C (PKC) is comprised of a family of signal-regulated enzymes that play pleiotropic roles in the control of many physiological and pathological responses.
Susan F. Steinberg
doaj   +1 more source

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