Results 41 to 50 of about 512,141 (378)

SRC and STAT Pathways [PDF]

Journal of Thoracic Oncology, 2006
Members of the Src family of protein tyrosine kinases (SRC) can link signaling initiated by growth factor, integrin, and cytokine receptors on the surface of cells to their downstream effector signaling cascades (Figure 1).1 Each protein consists of an amino-terminal domain that can be myristoylated, an SH2 and SH3 domain, a tyrosine kinase domain, and
openaire   +3 more sources

Effects of Short Range Correlations on Ca Isotopes [PDF]

, 1996
The effect of Short Range Correlations (SRC) on Ca isotopes is studied using a simple phenomenological model. Theoretical expressions for the charge (proton) form factors, densities and moments of Ca nuclei are derived. The role of SRC in reproducing the
A. Andl, A. Fabrocini, A. Ramos, B. Frois, B. Frois, B.A. Brown, C.B. Daskaloyannis, D. Van Neck, D.S. Lewart, E.W. Otten, F. Barranco, F. Malaguti, G. A. Lalazissis, G.A. Lalazissis, G.A. Lalazissis, G.A. Lalazissis, G.A. Lalazissis, G.A. Lalazissis, H. Chandra, H.J. Emrich, I. Talmi, J. Billowes, J. Blomqvist, J. Mougey, J.W. Clark, K. Takayanagi, L. Zamick, L.J. Tassie, M. Gaudin, M.L. Ristig, M.V. Stoitsov, P.-O. Löwdin, P.K.A. de Witt Huberts, R. Bhattacharya, R. Jastrow, R.F. Frosch, S. Adachi, S. E. Massen, S.E. Massen, S.E. Massen, S.E. Massen, S.E. Massen, V. R. Pandharipande   +42 more
core   +2 more sources

Adhesion to fibronectin regulates Hippo signaling via the FAK–Src–PI3K pathway

Journal of Cell Biology, 2015
Fibronectin adhesion stimulation of focal adhesion kinase (FAK)–Src–PI3K is an upstream regulatory branch of the Hippo pathway and stimulates the activity and nuclear localization of YAP in a Lats-dependent manner.
Nam‐Gyun Kim, B. Gumbiner
semanticscholar   +1 more source

Prostaglandin E2-dependent activation of Src-Stat3 signal pathway in human lung adenocarcinoma cells

Czech Journal of Food Sciences, 2004
Accumulating evidence suggests that overproduction of prostaglandin (PG) E2 attributable to induction of cyclooxygenase-2 plays an important role in the development of lung adenocarcinoma.
I. Nagamine, T. Yano, K. Endoh, T. Yamaki, T. Morimura, M. Miyahara, H. T. T. Nguyen, J. Pokorný, H. Sakurai   +8 more
doaj   +1 more source

The Prognostic Significance of Src and p-Src Expression in Patients with Osteosarcoma [PDF]

Medical Science Monitor, 2015
The expression of Src and phospho-Src (p-Src) is closely related to tumor invasion and metastasis. The aim of the present study was to investigate the expression of these molecules in osteosarcoma and their relationship with each other, to provide a theoretical basis to understand the prognosis of osteosarcoma.We selected surgically resected ...
Yuanlong Xie, Yi Zhang, Lin Cai, Chao Hu, Lei Yan, Jun Lei, Zhouming Deng   +6 more
openaire   +3 more sources

Src Inhibits the Hippo Tumor Suppressor Pathway through Tyrosine Phosphorylation of Lats1.

Cancer Research, 2017
The Hippo pathway regulates cell proliferation, apoptosis, and stem cell self-renewal, and its inactivation in animal models causes organ enlargement followed by tumorigenesis.
Y. Si, Xinyan Ji, Xiaolei Cao, Xiaoming Dai, Lingyi Xu, Hongxia Zhao, Xiaocan Guo, Huan Yan, Haitao Zhang, Chu Zhu, Qi Zhou, M. Tang, Zongping Xia, Li Li, Y. Cong, Sheng Ye, T. Liang, Xin-Hua Feng, Bin Zhao   +18 more
semanticscholar   +1 more source

Maternal Protein Restriction Alters the Expression of Proteins Related to the Structure and Functioning of the Rat Offspring Epididymis in an Age-Dependent Manner

Frontiers in Cell and Developmental Biology, 2022
Nutrition is an environmental factor able to activate physiological interactions between fetus and mother. Maternal protein restriction is able to alter sperm parameters associated with epididymal functions.
Marilia Martins Cavariani, Talita de Mello Santos, Luiz Gustavo de Almeida Chuffa, Patrícia Fernanda Felipe Pinheiro, Wellerson Rodrigo Scarano, Raquel Fantin Domeniconi   +5 more
doaj   +1 more source

Quantitative Expression of C-Type Lectin Receptors in Humans and Mice [PDF]

, 2012
C-type lectin receptors, their adaptor molecules and S-type lectins (galectins) are involved in the recognition of glycosylated self-antigens and pathogens.
Akira, Anders, Bjorge, Camby, Caminschi, Christoph Römmele, Elola, Ferwerda, Geijtenbeek, Gingras, Gringhuis, Gross, Hans-Joachim Anders, Heil, Heni Eka Susanti, Hornung, Kimbrell, Kock, Kono, Kronin, Kulkarni, Lassen, Lech, Lech, Lech, Lopez-Guisa, Maciej Lech, Medzhitov, Mocsai, Osorio, Patole, Rakoff-Nahoum, Regina Gröbmayr, Roman Günthner, Schreibelt, Skuginna, Van Vliet, Wagner, Zarember, Zhang   +39 more
core   +5 more sources

Syntenin mediates SRC function in exosomal cell-to-cell communication

Proceedings of the National Academy of Sciences of the United States of America, 2017
Significance Viral-like nanovesicles of endosomal origin, or “exosomes,” are newly recognized vehicles of signals that cells use to communicate, in various systemic diseases, including cancer. Yet the molecular mechanisms that regulate the biogenesis and
N. Imjeti, Kerstin Menck, A. L. Egea-Jimenez, C. Lecointre, F. Lembo, Habib Bouguenina, A. Badache, R. Ghossoub, G. David, S. Roche, P. Zimmermann   +10 more
semanticscholar   +1 more source

The Src-Family Kinases SRC and BLK Contribute to the CLDN6-Adhesion Signaling

Cells, 2023
Cell adhesion molecules, including integrins, cadherins, and claudins (CLDNs), are known to activate Src-family kinases (SFKs) that organize a variety of physiological and pathological processes; however, the underlying molecular basis remains unclear. Here, we identify the SFK members that are coupled with the CLDN6-adhesion signaling.
Naoki Ichikawa-Tomikawa, Kotaro Sugimoto, Korehito Kashiwagi, Hideki Chiba   +3 more
openaire   +3 more sources