Results 31 to 40 of about 242,192 (301)

Role of Src and Cortactin in Pemphigus Skin Blistering

Frontiers in Immunology, 2019
Autoantibodies against desmoglein (Dsg) 1 and Dsg3 primarily cause blister formation in the autoimmune disease pemphigus vulgaris (PV). Src was proposed to contribute to loss of keratinocyte cohesion.
Daniela Kugelmann, Vera Rötzer, Elias Walter, Desalegn Tadesse Egu, Michael Tobias Fuchs, Franziska Vielmuth, Hilda Vargas-Robles, Michael Schnoor, Michael Hertl, Rüdiger Eming, Klemens Rottner, Klemens Rottner, Ansgar Schmidt, Volker Spindler, Volker Spindler, Jens Waschke   +15 more
doaj   +1 more source

Opposing effects of inhibitors of Aurora-A and EGFR in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Frontiers in Oncology, 2015
Aurora-A kinase (AURKA) overexpression in numerous tumors induces aneuploidy, in part because of cytokinetic defects. Alisertib and other small-molecule inhibitors targeting AURKA are effective in some patients as monotherapies or combination therapies.
Anna S Nikonova, Alexander Y Deneka, Alexander Y Deneka, Louisa eEckman, Meghan C Kopp, Harvey H Hensley, Brian L Egleston, Erica eGolemis   +7 more
doaj   +1 more source

Technology of two-dimensional bioimpedance analysis of the human body composition

Journal of Electrical Bioimpedance, 2021
The BIA primary result sheets as a rule contain one-dimensional graphical scales with a selected area of normal values. In 1994, Piccoli et al. proposed BIVA, an alternative form of BIA data presentation, where two bioimpedance parameters are considered ...
Shchelykalina S. P., Nikolaev D. V., Kolesnikov V. A., Korostylev K. A., Starunova O. A.   +4 more
doaj   +1 more source

Targeting Src in endometriosis-associated ovarian cancer [PDF]

, 2016
The SRC proto-oncogene is commonly overexpressed or activated during cancer development. Src family kinase inhibitors are approved for the treatment of certain leukemias, and are in clinical trials for the treatment of solid tumors.
Gayther, Simon A., Sowter, H, Mhawech-Fauceglia, Paulette, Sowter, Heidi M., Lawrenson, K, Manek, R, Pakzamir, E, Mhawech-Fauceglia, P, Pakzamir, Elham, Gayther, S, Lawrenson, Kate, Manek, Roxanne, Pejovic, Tanja, Pejovic, T   +13 more
core   +1 more source

Prostaglandin E2-dependent activation of Src-Stat3 signal pathway in human lung adenocarcinoma cells

Czech Journal of Food Sciences, 2004
Accumulating evidence suggests that overproduction of prostaglandin (PG) E2 attributable to induction of cyclooxygenase-2 plays an important role in the development of lung adenocarcinoma.
I. Nagamine, T. Yano, K. Endoh, T. Yamaki, T. Morimura, M. Miyahara, H. T. T. Nguyen, J. Pokorný, H. Sakurai   +8 more
doaj   +1 more source

Correction: Niederhauser et al. Anti-SARS-CoV-2 Antibody Development over Four Years in Blood Donors. Viruses 2025, 17, 1292

Viruses
In the original publication [...]
Christoph Niederhauser, Nadja Widmer, Caroline Tinguely, Franziska Suter Riniker, Stefano Fontana, Andreas Buser, Sophie Waldvogel, Jutta Thierbach, Max Züger, Peter Gowland   +9 more
doaj   +1 more source

Anti-SARS-CoV-2 Antibody Development over Four Years in Blood Donors

Viruses
The blood donor population has great potential to serve as a sentinel system for the general population. The data presented in this study of a survey of the seroprevalence of Anti-SARS-CoV-2 antibodies in Switzerland are an illustrative example of this ...
Christoph Niederhauser, Nadja Widmer, Caroline Tinguely, Franziska Suter Riniker, Stefano Fontana, Andreas Buser, Sophie Waldvogel, Jutta Thierbach, Max Züger, Peter Gowland   +9 more
doaj   +1 more source

ESSENTIAL ROLE OF LYN IN FIBROSIS

Frontiers in Physiology, 2016
Fibrotic disorders involve replacement of normal parenchyma with myofibroblasts, which deposit connective tissue, leading to obliteration of the function of the underlying organ.
Hung Pham, Chiara Birtolo, Chintan Chheda, Wendy Yang, Maria Rodriguez, Sandy Liu, Gabriele Gugliotta, Michael Lewis, Vincenzo Cirulli, Stephen Pandol, Andrzej Ptasznik   +10 more
doaj   +1 more source

Interplay of Matrix Stiffness and c-SRC in Hepatic Fibrosis.

Frontiers in Physiology, 2015
Introduction:In liver fibrosis activation of hepatic stellate cells (HSC) comprises phenotypical change into profibrotic and myofibroplastic cells with increased contraction and secretion of extracellular matrix (ECM) proteins.
Jan eGörtzen, Robert eSchierwagen, Jeanette eBierwolf, Sabine eKlein, Frank Erhard Uschner, Peter F. van der Ven, Dieter O. Fürst, Christian P. Strassburg, Wim eLaleman, Jörg-Matthias ePollok, Jonel eTrebicka, Jonel eTrebicka   +11 more
doaj   +1 more source

Maternal Protein Restriction Alters the Expression of Proteins Related to the Structure and Functioning of the Rat Offspring Epididymis in an Age-Dependent Manner

Frontiers in Cell and Developmental Biology, 2022
Nutrition is an environmental factor able to activate physiological interactions between fetus and mother. Maternal protein restriction is able to alter sperm parameters associated with epididymal functions.
Marilia Martins Cavariani, Talita de Mello Santos, Luiz Gustavo de Almeida Chuffa, Patrícia Fernanda Felipe Pinheiro, Wellerson Rodrigo Scarano, Raquel Fantin Domeniconi   +5 more
doaj   +1 more source