Results 31 to 40 of about 260,978 (272)

Correction: Niederhauser et al. Anti-SARS-CoV-2 Antibody Development over Four Years in Blood Donors. Viruses 2025, 17, 1292

Viruses
In the original publication [...]
Christoph Niederhauser, Nadja Widmer, Caroline Tinguely, Franziska Suter Riniker, Stefano Fontana, Andreas Buser, Sophie Waldvogel, Jutta Thierbach, Max Züger, Peter Gowland   +9 more
doaj   +1 more source

ESSENTIAL ROLE OF LYN IN FIBROSIS

Frontiers in Physiology, 2016
Fibrotic disorders involve replacement of normal parenchyma with myofibroblasts, which deposit connective tissue, leading to obliteration of the function of the underlying organ.
Hung Pham, Chiara Birtolo, Chintan Chheda, Wendy Yang, Maria Rodriguez, Sandy Liu, Gabriele Gugliotta, Michael Lewis, Vincenzo Cirulli, Stephen Pandol, Andrzej Ptasznik   +10 more
doaj   +1 more source

The Role of the Src Homology 3-Src Homology 2 Interface in the Regulation of Src Kinases [PDF]

Journal of Biological Chemistry, 2001
The regulatory fragment of Src kinases, comprising Src homology (SH) 3 and SH2 domains, is responsible for controlled repression of kinase activity. We have used a multidisciplinary approach involving crystallography, NMR, and isothermal titration calorimetry to study the regulatory fragment of Fyn (FynSH32) and its interaction with a physiological ...
Arold, S.T., Ulmer, T.S., Mulhern, T.D., Werner, J.M., Ladbury, J.E., Campbell, I.D., Noble, M.E.M.   +6 more
openaire   +4 more sources

Prevalence of Acute Hepatitis E Virus Infections in Swiss Blood Donors 2018–2020

Viruses
Introduction: Hepatitis E virus (HEV) genotype 3 is the major cause of acute viral hepatitis in several European countries. It is acquired mainly by ingesting contaminated pork, but has also been reported to be transmitted through blood transfusion ...
Christoph Niederhauser, Peter Gowland, Nadja Widmer, Soraya Amar EL Dusouqui, Maja Mattle-Greminger, Jochen Gottschalk, Beat M. Frey   +6 more
doaj   +1 more source

Interplay of Matrix Stiffness and c-SRC in Hepatic Fibrosis.

Frontiers in Physiology, 2015
Introduction:In liver fibrosis activation of hepatic stellate cells (HSC) comprises phenotypical change into profibrotic and myofibroplastic cells with increased contraction and secretion of extracellular matrix (ECM) proteins.
Jan eGörtzen, Robert eSchierwagen, Jeanette eBierwolf, Sabine eKlein, Frank Erhard Uschner, Peter F. van der Ven, Dieter O. Fürst, Christian P. Strassburg, Wim eLaleman, Jörg-Matthias ePollok, Jonel eTrebicka, Jonel eTrebicka   +11 more
doaj   +1 more source

p160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain [PDF]

, 2008
Transcriptional activation involves the ordered recruitment of coactivators via direct interactions between distinct binding domains and recognition motifs.
Coudevylle, N., Pfitzner, E., Muenz, Tobias, Pfitzner, Edith, Becker, Stefan, Coudevylle, Nicolas, Münz, Tobias, Lodrini, M., Becker, S., Munz, T., Griesinger, C., Lodrini, Marco, Griesinger, Christian   +12 more
core   +1 more source

Maternal Protein Restriction Alters the Expression of Proteins Related to the Structure and Functioning of the Rat Offspring Epididymis in an Age-Dependent Manner

Frontiers in Cell and Developmental Biology, 2022
Nutrition is an environmental factor able to activate physiological interactions between fetus and mother. Maternal protein restriction is able to alter sperm parameters associated with epididymal functions.
Marilia Martins Cavariani, Talita de Mello Santos, Luiz Gustavo de Almeida Chuffa, Patrícia Fernanda Felipe Pinheiro, Wellerson Rodrigo Scarano, Raquel Fantin Domeniconi   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Functional dissection of transformation by c‐Src and v‐Src [PDF]

Genes to Cells, 2007
The c‐src proto‐oncogene product, c‐Src, is frequently over‐expressed and activated in various human malignant cancers, implicating a role for c‐Src in cancer progression. To verify the role of c‐Src, we analyzed the transforming ability of c‐Src in mouse embryonic fibroblasts that lack Csk, a negative regulator of Src family kinases.
Chitose, Oneyama, Tomoya, Hikita, Shigeyuki, Nada, Masato, Okada   +3 more
openaire   +2 more sources

HEV in Blood Donors in Switzerland: The Route to Safe Blood Products

Pathogens
The hepatitis E virus (HEV) is an emerging infectious disease with zoonotic potential, causing acute hepatitis in humans. Infections in healthy individuals are often acute, self-limiting and asymptomatic, thus leading to the underdiagnosis of HEV ...
Mauro Serricchio, Peter Gowland, Nadja Widmer, Martin Stolz, Christoph Niederhauser   +4 more
doaj   +1 more source