Results 41 to 50 of about 242,192 (301)

HEV in Blood Donors in Switzerland: The Route to Safe Blood Products

open access: yesPathogens
The hepatitis E virus (HEV) is an emerging infectious disease with zoonotic potential, causing acute hepatitis in humans. Infections in healthy individuals are often acute, self-limiting and asymptomatic, thus leading to the underdiagnosis of HEV ...
Mauro Serricchio   +4 more
doaj   +1 more source

Assessing the Capability of Adaptive Neuro Fuzzy Interference System (ANFIS) in Estimating the Amount of Suspended Sediment Load and its Comparison with Two Models of Artificial Neutral Fuzzy Inference System Case study: Zarine rood, South east basin of Urmia Lake [PDF]

open access: yesجغرافیا و توسعه, 2015
Load sediment transport in rivers is important according to their role in pollution, Reservoir filling, hydroelectric equipment life, Fish and other hydrological issues.
Alimohamad Khorshiddoost   +2 more
doaj   +1 more source

On the 50th anniversary of the Scientific Research Company “Electron-Carat”

open access: yesTekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2022
The article is dedicated to the Scientific Research Company "Electron-Carat", which was founded in 1972 as the Lviv Research and Development Institute of Materials - the leading developer of the state-of-art materials.
Mykola Vakiv
doaj   +1 more source

Functional dissection of transformation by c‐Src and v‐Src [PDF]

open access: yesGenes to Cells, 2007
The c‐src proto‐oncogene product, c‐Src, is frequently over‐expressed and activated in various human malignant cancers, implicating a role for c‐Src in cancer progression. To verify the role of c‐Src, we analyzed the transforming ability of c‐Src in mouse embryonic fibroblasts that lack Csk, a negative regulator of Src family kinases.
Chitose, Oneyama   +3 more
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Effect of Src kinase inhibition on metastasis and tumor angiogenesis in human pancreatic cancer [PDF]

open access: yes, 2007
Tumor angiogenesis is a process that requires migration, proliferation, and differentiation of endothelial cells. We hypothesized that decrease in pancreatic tumor growth due to inhibition of src activity is associated with the inability of src kinase to
Ischenko, Ivan
core  

Cbl-associated protein is tyrosine phosphorylated by c-Abl and c-Src kinases

open access: yes, 2009
Background: The c-Cbl-associated protein (CAP), also known as ponsin, localizes to focal adhesions and stress fibers and is involved in signaling events.
Tomasovic, Ana   +11 more
core   +1 more source

EGF regulates tyrosine phosphorylation and membrane-translocation of the scaffold protein Tks5 [PDF]

open access: yes, 2013
Background: Tks5/FISH is a scaffold protein comprising of five SH3 domains and one PX domain. Tks5 is a substrate of the tyrosine kinase Src and is required for the organization of podosomes/invadopodia implicated in invasion of tumor cells.
Geiszt, Miklós   +5 more
core   +1 more source

Prevalence of Acute Hepatitis E Virus Infections in Swiss Blood Donors 2018–2020

open access: yesViruses
Introduction: Hepatitis E virus (HEV) genotype 3 is the major cause of acute viral hepatitis in several European countries. It is acquired mainly by ingesting contaminated pork, but has also been reported to be transmitted through blood transfusion ...
Christoph Niederhauser   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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