Results 11 to 20 of about 260,978 (272)
Regulation of Mint1-dependent APP trafficking by N1-Src [PDF]
, 2012 Alzheimer’s disease (AD) is a neurodegenerative disease characterised by the accumulation of Amyloid-beta (Aβ) plaques and neurofibrillary tangles. Aβ plaques form as a result of improper trafficking and processing of the Amyloid precursor protein (APP).
Black, Hannah Lucy
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Proceedings of the international conference on Supercomputing, 2011 OpenSHMEM is a PGAS programming library implementing an RMA-based point-to-point and collective communication paradigm which decouples data motion from synchronization. This results in a more scalable programming model than more common two-sided paradigms such as MPI. The OpenSHMEM project arose in an effort to standardize among several implementations
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Phosphorylated c-Src in the nucleus is associated with improved patient outcome in ER-positive breast cancer [PDF]
, 2008 Elevated c-Src protein expression has been shown in breast cancer and <i>in vitro</i> evidence suggests a role in endocrine resistance. To investigate whether c-Src is involved in endocrine resistance, we examined the expression of both total
Cooke, T.G. +20 more
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Oncogene, 2004 More than a quarter of a century has elapsed since the identification of the c-src proto-oncogene. During that period, we have learned that cancer arises as the result of mutations in proto-oncogenes and tumor suppressor genes, and we are now seeing the first fruits of these discoveries, in the form of targeted therapies directed against activated ...
openaire +2 more sources
Effect of Src kinase inhibition on metastasis and tumor angiogenesis in human pancreatic cancer [PDF]
, 2007 Tumor angiogenesis is a process that requires migration, proliferation, and differentiation of endothelial cells. We hypothesized that decrease in pancreatic tumor growth due to inhibition of src activity is associated with the inability of src kinase to
Ischenko, Ivan
core +1 more source
LAMININS IN COLORECTAL CANCER: EXPRESSION, FUNCTION, PROGNOSTIC POWER AND MOLECULAR MECHANISMS
Исследования и практика в медицине, 2017 Extracellular matrix (ECM) proteins are a major component of the tumor stroma. Laminins emerge as one of the main families of ECM proteins with signaling properties.
S. A. Rodin, D. V. Maltseva
doaj +1 more source
SRC promotes lipogenesis: implications for obesity and breast cancer
Molecular & Cellular Oncology, 2021 Remodeling of lipid metabolism has been implicated in cancers; however, it remains obscure how the lipid metabolic pathways are altered by oncogenic signaling to affect tumor development. We have recently shown that proto-oncogene tyrosine-protein kinase
Shu-Yong Lin, Sheng-Cai Lin
doaj +1 more source
Epidermal Growth Factor Receptor substrate 8 (Eps8) controls Src/FAK-dependent phenotypes in squamous carcinoma cells [PDF]
, 2014 Eps8 is an actin regulatory scaffold protein increased in Squamous Cell Carcinoma (SCC) cells. It forms a complex with both Focal Adhesion Kinase (FAK) and c-Src in SCC cells derived from the DMBA/TPA model of skin carcinogenesis.
Schoenherr, Christina +13 more
core +1 more source
, 2023 We will conduct a scoping exercise and map the available evidence resources related to COVID-19 along with the other pandemics. We will search (a specific topic-related search using search engines in particular Google based on an electronic search strategy developed a priori and also do a manual search of websites of selected agencies such as COVID-END,
Mantri, Swati, Shirodkar, Sujata
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Light fragments from (C + Be) interactions at 0.6 GeV/nucleon
EPJ Web of Conferences, 2016 Nuclear fragments emitted at 3.5° in 12C fragmentation at 0.6 GeV/nucleon have been measured. The spectra obtained are used for testing the predictions of four ion-ion interaction models: INCL++, BC, LAQGSM03.03 and QMD as well as for the comparison with
Abramov B.M. +12 more
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