Results 71 to 80 of about 61,368 (147)

Expression of myeloid Src-family kinases is associated with poor prognosis in AML and influences Flt3-ITD kinase inhibitor acquired resistance.

PLoS ONE, 2019
Unregulated protein-tyrosine kinase signaling is a common feature of AML, often involving mutations in Flt3 and overexpression of myeloid Src-family kinases (Hck, Fgr, Lyn).
Ravi K Patel, Mark C Weir, Kexin Shen, Daniel Snyder, Vaughn S Cooper, Thomas E Smithgall   +5 more
doaj   +1 more source

Regulation of Src family kinases by muscarinic acetylcholine receptors in heterologous cells and neurons. [PDF]

Front Mol Neurosci, 2023
Mao LM, Young L, Chu XP, Wang JQ.
europepmc   +1 more source

EGFR-to-Src family tyrosine kinase switching in proliferating-DTP TNBC cells creates a hyperphosphorylation-dependent vulnerability to EGFR TKI

Cancer Cell International
Triple-Negative Breast Cancer (TNBC) is the most aggressive type of breast malignancy, with chemotherapy as the only mainstay treatment. TNBC patients have the worst prognoses as a large fraction of them do not achieve complete pathological response post-
Nazia Chaudhary, Bhagya Shree Choudhary, Anusha Shivashankar, Subhakankha Manna, Khyati Ved, Shagufa Shaikh, Sonal Khanna, Jeetnet Baar, Jagruti Dani, Sarthak Sahoo, R. Soundharya, Mohit Kumar Jolly, Nandini Verma   +12 more
doaj   +1 more source

ArtinM Cytotoxicity in B Cells Derived from Non-Hodgkin's Lymphoma Depends on Syk and Src Family Kinases. [PDF]

Int J Mol Sci, 2023
Barboza BR, Thomaz SMO, Junior AC, Espreafico EM, Miyamoto JG, Tashima AK, Camacho MF, Zelanis A, Roque-Barreira MC, da Silva TA.   +9 more
europepmc   +1 more source

c-Kit Receptor Maintains Sensory Axon Innervation of the Skin through Src Family Kinases. [PDF]

J Neurosci, 2022
Tuttle AM, Pomaville MB, Delgado KC, Wright KM, Nechiporuk AV.   +4 more
europepmc   +1 more source

Identification of Src Family Kinases as Potential Therapeutic Targets for Chemotherapy-Resistant Triple Negative Breast Cancer. [PDF]

Cancers (Basel), 2022
Kohale IN, Yu J, Zhuang Y, Fan X, Reddy RJ, Sinnwell J, Kalari KR, Boughey JC, Carter JM, Goetz MP, Wang L, White FM.   +11 more
europepmc   +1 more source

Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy. [PDF]

Mol Cancer Ther, 2022
Sinnett-Smith J, Anwar T, Reed EF, Teper Y, Eibl G, Rozengurt E.   +5 more
europepmc   +1 more source

Repurposing Tyrosine Kinase Inhibitors for Sickle Cell Disease: Focus on Band 3 Phosphorylation

Biomedicines
Sickle cell disease (SCD) is an autosomal recessive hemoglobin disorder that is mainly characterized by the presence of hemoglobin S (HbS; point mutation [Glu6Val] in the beta-globin gene). Under deoxygenated conditions, HbS polymerizes and serves as the
Raj Gupta, Neha Mishra, Manisha Madkaikar, Rohit Kumar Singh   +3 more
doaj   +1 more source

Ephrin B Activate Src Family Kinases in Fibroblasts Inducing Stromal Remodeling in Prostate Cancer. [PDF]

Cancers (Basel), 2022
Kakarla M, ChallaSivaKanaka S, Dufficy MF, Gil V, Filipovich Y, Vickman R, Crawford SE, Hayward SW, Franco OE.   +8 more
europepmc   +1 more source

Src family kinases inhibit differentiation of intestinal epithelial cells through the Hippo effector YAP1. [PDF]

Biol Open, 2021
Fallah S, Beaulieu JF.
europepmc   +1 more source