Results 41 to 50 of about 95,517 (265)

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng, Weilong Lin, Zean Li, Ruilin Zhuang, Shengmeng Peng, Bingheng Li, Bingliang Chen, Yong Luo, Yuan Ou, Wei Zhuang, Tao Du, Kaiwen Li, Hai Huang   +12 more
wiley   +1 more source

To Compare and Evaluate the Efficacy of 1% Alendronate Gel and 10% Doxycycline Gel as an Adjunct to SRP in Patients with Chronic Periodontitis: A Randomized Controlled Clinical Trial

Journal of Pharmacy and Bioallied Sciences
Background: Modern medicine has advanced drug delivery strategies for improved treatment outcomes with minimal systemic side effects. Local drug delivery is a promising approach, targeting therapeutic agents to specific tissues or organs, optimizing ...
Laloo Phassang, Radhika Kapoor, Prashant Tyagi, Amit Wadhawan   +3 more
doaj   +1 more source

Compensating Complete Loss of Signal Recognition Particle During Co-translational Protein Targeting by the Translation Speed and Accuracy

Frontiers in Microbiology, 2021
Signal recognition particle (SRP) is critical for delivering co-translational proteins to the bacterial inner membrane. Previously, we identified SRP suppressors in Escherichia coli that inhibit translation initiation and elongation, which provided ...
Liuqun Zhao, Liuqun Zhao, Gang Fu, Gang Fu, Gang Fu, Yanyan Cui, Zixiang Xu, Zixiang Xu, Tao Cai, Dawei Zhang, Dawei Zhang, Dawei Zhang, Dawei Zhang   +12 more
doaj   +1 more source

PABRE-Proj: applying patterns in requirements elicitation [PDF]

, 2013
© 2013 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes,creating new ...
Franch Gutiérrez, Javier, Palomares Bonache, Cristina, Quer, Carme   +2 more
core   +1 more source

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

Advanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang, Yuwei Xu, Yufei Lan, Zhen Xiong, Zhibin Yi, Runyuan Wu, Cunzhen Li, Ying Du, Hui Guo, Yingchi Yang, Zusen Fan   +10 more
wiley   +1 more source

Effectiveness of ozone in the management of chronic periodontitis: A clinico-microbiological study

Journal of Dr. NTR University of Health Sciences
Aim: To evaluate the efficacy of ozonated water with NSPT compared with scaling and root planing (SRP) alone in treating chronic periodontitis. Settings and Design: The current study is a double-masked, randomized clinical trial.
S. V. V. S. Musalaiah, Pavuluri Aravind Kumar, P Harish Prabhudev, Joseph Kishore Reddy, Narendra Mandalapu, Haneesha Patcha   +5 more
doaj   +1 more source

Deployment of the consultation-liaison model in adult and child-adolescent psychiatry and its impact on improving mental health treatment

BMC Family Practice, 2021
Background Little information exists on the perceptions of psychiatrists regarding the implementation and various impacts of the consultation-liaison model.
M.-J. Fleury, G. Grenier, L. Gentil, P. Roberge   +3 more
doaj   +1 more source

Design exploration and performance strategies towards power-efficient FPGA-based achitectures for sound source localization [PDF]

, 2019
Many applications rely on MEMS microphone arrays for locating sound sources prior to their execution. Those applications not only are executed under real-time constraints but also are often embedded on low-power devices.
Braeken, An, da Silva Gomes, Bruno, Segers, Laurent, Steenhaut, Kris, Touhafi, Abdellah   +4 more
core   +1 more source

On the Ordering Mechanism of Cu+ in 2D van der Waals Multiferroic CuCrP2S6

Advanced Science, EarlyView.
Temperature‐dependent X‐ray single‐crystal diffuse scattering measurements of CuCrP2S6 in the (H, K, 0) plane reveal the gradual emergence and strengthening of short‐range order upon cooling from 230 to 170 K. At intermediate temperatures, diffuse features become pronounced and eventually lock into sharp incommensurate satellite reflections, indicating
Jiasen Guo, Yongqiang Cheng, Michael A. Susner, Ryan P. Siebenaller, Zachary Morgan, Feng Ye   +5 more
wiley   +1 more source

Directly Indecomposables in Semidegenerate Varieties of Connected po-Groupoids

, 2008
We study varieties with a term-definable poset structure, "po-groupoids". It is known that connected posets have the "strict refinement property" (SRP).
D. Vaggione, D. Vaggione, J. Kollar, J.A. Gerhard, J.A. Gerhard, Pedro Sánchez Terraf, R. McKenzie, R. Willard, R. Willard   +8 more
core   +1 more source