Results 131 to 140 of about 53,752 (247)

Advances in large DNA fragment assembly for microbial cell factory engineering

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang   +5 more
wiley   +1 more source

Dengue Virus Capsid Protein Interaction With Nucleic Acids. [PDF]

open access: yesBiofactors
Silva NM   +7 more
europepmc   +1 more source

Technologies for engineering repetitive DNA

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long‐read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth.
Shuting Ma, Yali Cui, Yi Wu
wiley   +1 more source

Writing Big in Plant Genomes: Advances, Challenges and Strategies for Targeted Large‐Fragment DNA Insertion

open access: yesPlant, Cell &Environment, Volume 49, Issue 9, Page 6506-6520, September 2026.
ABSTRACT Precise genome editing has transformed plant biology and crop improvement by enabling targeted modification of endogenous loci. Beyond gene knockout and base editing, the site‐specific insertion of exogenous DNA, particularly large DNA fragments, has become a central goal for engineering complex traits, reconstructing metabolic pathways and ...
Fengfeng Zhang   +6 more
wiley   +1 more source

WAVE2 and REST/NRSF Regulate Clustered Gene Expression by Maintaining Heterochromatin Organization

open access: yesThe FASEB Journal, Volume 40, Issue 16, 31 August 2026.
We identify WAVE2 as a key regulator of clustered gene expression via heterochromatin organization. Loss of WAVE2 leads to the expression of Pcdhα genes shifting from stochastic to ubiquitous isoforms, concurrent with altered promoter accessibility. REST/NRSF similarly regulates Pcdhα gene expression by organizing heterochromatin, indicating distinct ...
Leyang Wang   +4 more
wiley   +1 more source

Bioproduction of ∼10 knt single-stranded DNA for constructing large DNA origami structures. [PDF]

open access: yesMater Today Bio
Lu M   +11 more
europepmc   +1 more source

Dynamic Control of Nucleic Acids Self‐Assembly and Expression Using Photoswitches

open access: yesChemistry – A European Journal, Volume 32, Issue 31, 18 August 2026.
We review here the recent progress made in the design of molecular photoswitches, and highlight their implementation for the dynamic control over nucleic acids self‐assembly and expression. ABSTRACT Synthetic nucleic acids have become readily available and now constitute versatile building blocks in materials science—where they can be used to engineer ...
Noemí Nogal   +4 more
wiley   +1 more source

DNA Assembly Templated by Chiral Nanotube Lattices: From Helix to Rings. [PDF]

open access: yesJ Am Chem Soc
Sonani RR   +6 more
europepmc   +1 more source

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