Results 131 to 140 of about 66,303 (280)
Advanced Science, EarlyView.USP4 stabilizes CHAF1B by limiting K48‐linked ubiquitination. Stabilized CHAF1B supports UHRF1‐associated K63‐linked SETDB1 ubiquitination and cytoplasmic redistribution, whereas CHAF1B loss favors VHL‐dependent K11‐associated degradative ubiquitination and proteasomal loss of SETDB1.
Saiyan Bian +9 more
wiley +1 more source
The C‐terminus of the ssDNA binding protein of phage T7 modulates its ssDNA‐binding activity
The FASEB Journal, 2006 The gene 2.5 (gp2.5), the ssDNA‐binding protein of phage T7, is indispensable for phage growth and a key component of the T7 DNA replication fork. Gp2.5 binds ssDNA, interacts with T7 DNA polymerase, and T7 helicase/primase, and is essential for coordination of leading and lagging strand DNA synthesis.
Boriana Davidova Marintcheva +1 more
openaire +1 more source
UNG2 and RPA Activity on ssDNA-dsDNA Junctions [PDF]
, 2022 Uracil DNA glycosylase, or UNG2, is an enzyme that is involved in DNA repair. Its primary job is to eliminate harmful uracil bases from DNA strands. To do this, the enzyme is assisted by replication protein A (RPA).
Chen, Kathy +2 more
core
Advanced Electronic Materials, EarlyView.This review summarizes the developments in field‐effect transistor (FET)‐based dual‐mode sensor platforms and what can be learned from them. It identifies charge as a crucial factor in biomolecular interactions at interfaces, outlines the challenges of hybrid systems, and highlights their benefits.
Roger Hasler +4 more
wiley +1 more source
A Novel Electrochemical Biosensor Based on DNA for Rapid and Selective Detection of Cadmium
International Journal of Electrochemical Science, 2015 A sensitive platform for the rapid detection of cadmium basing on single-stranded DNA modified Au electrode (ssDNA/Au) was presented. The ssDNA/Au biosensor screened 6 kinds of chemicals including cadmium salts, sodium salts, copper salts, magnesium ...
Jialin Qu +6 more
doaj +1 more source
Energy landscapes for simulated ssDNA–ssDBP and ssRNA–ssRBP complexes.
, 2019 The binding energy (Kcal mol-1) is plotted versus DSite and DConf for each of the ssDBP–ssDNA (top, red square) and ssRBP–ssRNA (bottom, blue square) complexes.
Arumay Pal (63524) +1 more
core +1 more source
Proof of ssDNA degraded from dsDNA for ET recombination
Biochemistry and Biophysics ReportsThe widely used ET recombination requires an ssDNA product degraded by Rac phage protein E588 from dsDNA for strand invasion. However, proof of the ssDNA product is still elusive. The study provided three levels of proof sequentially. The probable ssDNAs
Yuanxia Zheng +3 more
doaj +1 more source
Molecular Dissection of the Mechanism of ssDNA-binding Proteins [PDF]
, 2014 The maintenance of the integrity of DNA is crucial for life as any change could result in cellular abnormalities leading to disease. DNA is most stable as a double helix.
Binns, Kelly
core +1 more source
Model for Mec1 activation at RPA-covered ssDNA tracts.
, 2019 (A) ssDNA binding of Ddc2 increases Mec1 activity. ssDNA binding of Ddc2 triggers conformation changes of the entire Mec1-Ddc2 homodimer, resulting in structural changes of the kinase domain at the C-terminus of Mec1. K263 is involved in homodimerization
Patrick Sung (513951) +4 more
core +1 more source
Bacterial exonuclease III expands its enzymatic activities on single-stranded DNA
eLifeBacterial exonuclease III (ExoIII), widely acknowledged for specifically targeting double-stranded DNA (dsDNA), has been documented as a DNA repair-associated nuclease with apurinic/apyrimidinic (AP)-endonuclease and 3′→5′ exonuclease activities.
Hao Wang +10 more
doaj +1 more source