Electrochemical Science Advances, Volume 6, Issue 4, August 2026.ABSTRACT Rapid and sensitive detection of disease‐related biomarkers is critical for early diagnosis and appropriate treatment. However, conventional analytical methods are often time‐consuming and require complex procedures and skilled personnel.
Minju Ahn +4 more
wiley +1 more source
Effect of TAR hairpin stabilization on HIV-1 reverse transcription. [PDF]
J VirolDa Silva Amaral S +7 more
europepmc +1 more source
The Journal of Gene Medicine, Volume 28, Issue 8, August 2026.We successfully developed a highly efficient knock‐in adenovirus vector, AxPah‐6g‐cut. This vector cleaves not only the genomic target site but also the terminus of the donor DNA in the vector. When this vector was intravenously administered twice to phenylketonuria (Pahenu2) mice together with a Cas9‐expressing vector, AxCBCas9, it resulted in the ...
Megumi Yamaji +10 more
wiley +1 more source
Optimizing single molecule, real-time sequencing for enhanced characterization of adeno-associated viral vector genomes. [PDF]
Mol Ther AdvManz J +4 more
europepmc +1 more source
DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity
Small, Volume 22, Issue 43, 3 August 2026.DNA–enzyme hybrid nanostructures enable precise spatial and stoichiometric control over enzyme organization, offering a powerful platform to modulate catalytic activity. This review critically evaluates key mechanistic hypotheses, including proximity effects, microenvironment changes, confinement, and stabilization, as well as highlighting ...
Manar Elnaggar, Amelie Heuer‐Jungemann
wiley +1 more source
Correction to 'Casδ, an evolutionary transitional CRISPR system enables efficient genome editing across animals and plants'. [PDF]
Nucleic Acids Reseuropepmc +1 more source
Mechanism of single-strand annealing from native mass spectrometry and cryo-EM structures of RAD52 homolog Mgm101. [PDF]
Nucleic Acids ResWheat CT +5 more
europepmc +1 more source
Small Structures, Volume 7, Issue 8, August 2026.3D Bioprinted GelMA hydrogels incorporating polydeoxyribonucleotide (PDRN) offer a promising strategy for recovering volumetric muscle loss. This study reveals that single‐stranded PDRN significantly enhances myogenesis and accelerates muscle remodeling compared to double‐stranded forms.
Elif Beyza Demiray +11 more
wiley +1 more source
Spatiotemporal characterization of single-stranded DNA Intermediates after UV Irradiation: I: Post-replication gaps formed during slow growth. [PDF]
PLoS GenetSharma N +7 more
europepmc +1 more source
Recent Advances in the Molecular Mechanisms of Bacterial Anti‐Phage Defence Systems
Microbial Biotechnology, Volume 19, Issue 8, August 2026.Panoptes as an example for an antiphage system consists of OptS producing a cyclic dinucleotide that prevents activation of OptE, a transmembrane protein. Phage T4 infection introduces the sponge protein Acb2 that adsorbs the cyclic dinucleotide thus activating OptE which disrupts the cell membrane aborting phage infection.
Harald Brüssow
wiley +1 more source