Results 161 to 170 of about 66,303 (280)

Involvement of the OB-fold and the C-terminal acidic tip of SSB in its interaction with RecO from Thermus thermophilus HB8. [PDF]

J Biochem
Kobayashi K, Inoue M, Fukui K, Aono R, Ochi A, Masui R, Mihara H.   +6 more
europepmc   +1 more source

Amplifikation und Einsatz von ssDNA-Aptameren

Die wachsende Produktpalette von z. B. Pharmazeutika geht mit einer steigenden Nachfrage für hochsensitive/schonende Aufreinigungstechniken einher. Bisherige Verfahren führen oft zu geringer Reinheit und verminderter Bioaktivität, zeigen eine Limitation ...
Stadtmüller, Ralf, Tippkötter, Nils (Prof. Dr.-Ing.), Wollny, S., Ulber, Roland   +3 more
core   +1 more source

Patterning of Artificial Cell Populations Via Laser Induced Forward Transfer for Controlled and Localized Cargo Uptake and Release

Small, EarlyView.
Polypeptide‐based complex coacervate artificial cells were prepared in situ within a viscoelastic matrix and adhered to the biomaterial ink, which was subsequently LIFT‐printed. The artificial cells preserved their structural stability during printing and retained biologically relevant properties, showing controlled cargo uptake and release ...
Yiğitcan Sümbelli, Núria Ginés Rodriguez, Lars J. M. M. Paffen, Arjan Hazegh Nikroo, Riccardo Levato, Jan C. M. van Hest, Jos Malda   +6 more
wiley   +1 more source

Smart mesoporous silica nanoparticles for precision cancer therapy: Tumor targeting and stimuli‐responsive controlled release

Smart Molecules, EarlyView.
Smart mesoporous silica nanoparticles integrate tunable pore structures, molecular gates, targeting ligands, and stimuli‐responsive components to achieve controlled drug release for precision cancer therapy. This review highlights design principles, therapeutic applications, and future directions in immunotherapy, biodegradability, biosafety, and ...
Majdi Al‐Amili, Lei Lei, Zhu Jin
wiley   +1 more source

Widespread atypical UV-induced mutations form in single-stranded DNA. [PDF]

Sci Adv
Cordero C, Vandenberg BN, Mittelstadt I, Murch J, Laughery MF, Mieczkowski PA, Wyrick JJ, Roberts SA.   +7 more
europepmc   +1 more source

How We Simulate Nanopores

Small Methods, EarlyView.
Nanopore technology has revolutionized single‐molecule sensing, yet it suffers from an inherent interpretive challenge. Molecular dynamics has emerged as a go‐to method for determining the relationship between the structure of translocating molecules and the nanopore current signals.
Behzad Mehrafrooz, Xavier Mleziva, Meng Xu, Melika Shekari, Christopher Maffeo, Aleksei Aksimentiev   +5 more
wiley   +1 more source

HELQ & Hel308: ancient enzymes of DNA repair and recombination. [PDF]

Biochem Soc Trans
Lou-Hing A, Downs O, Allers T, Bolt EL.
europepmc   +1 more source

Two‐Dimensional Materials For Lateral Flow Assays: A Critical Review of Functional Roles and Translational Challenges

VIEW, EarlyView.
2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu, Ruping Liu, Na Gao, Jianxiao Zhu, Haowen Jiang, Shouzheng Jiao, Zhicheng Sun, Kai Shen, Gaolian Xu, Minghua Du, Ziyan Li, Yang Wang   +11 more
wiley   +1 more source

Domain dynamics within the PriA DNA helicase regulate DNA replication restart. [PDF]

Nucleic Acids Res
Deorio HR, Duckworth AT, Forsythe GR, Sung AY, Sandler SJ, Grant T, Keck JL.   +6 more
europepmc   +1 more source

Point of Care Testing and Recombinase Polymerase Amplification

Journal of Clinical Laboratory Analysis, EarlyView.
Manfred Weidmann, Ahmed Abd El Wahed
wiley   +1 more source