Results 11 to 20 of about 53,752 (247)
Details of ssDNA annealing revealed by an HSV-1 ICP8–ssDNA binary complex [PDF]
Nucleic Acids Research, 2013 Infected cell protein 8 (ICP8) from herpes simplex virus 1 was first identified as a single-strand (ss) DNA-binding protein. It is essential for, and abundant during, viral replication. Studies in vitro have shown that ICP8 stimulates model replication reactions, catalyzes annealing of complementary ssDNAs and, in combination with UL12 exonuclease ...
Tolun, Gökhan +3 more
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Acta Chimica Slovenica, 2021 A rapid and confident tool to identify and diagnose bacterial pathogens with more accuracy using DNA as fingerprints is necessary. Herein, we report a smart chemosensor having a terminal adenine sticking to the thymine of single-stranded DNA (ssDNA ...
Burak Şener +3 more
doaj +1 more source
Carbon Nanostructure-Based DNA Sensor Used for Quickly Detecting Breast Cancer-Associated Genes
Nanoscale Research Letters, 2022 The early diagnosis of breast cancer highly relies on the detection of mutant DNA at low concentrations. Förster resonance energy transfer (FRET) quenching may offer a solution to quickly detect a small amount of single-strand DNA (ssDNA) through the ...
Yingqi Zhang +4 more
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Concentration-dependent exchange of replication protein A on single-stranded DNA revealed by single-molecule imaging. [PDF]
PLoS ONE, 2014 Replication protein A (RPA) is a ubiquitous eukaryotic single-stranded DNA (ssDNA) binding protein necessary for all aspects of DNA metabolism involving an ssDNA intermediate, including DNA replication, repair, recombination, DNA damage response and ...
Bryan Gibb +6 more
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Viruses, 2022 APOBEC3 enzymes are polynucleotide deaminases, converting cytosine to uracil on single-stranded DNA (ssDNA) and RNA as part of the innate immune response against viruses and retrotransposons. APOBEC3G is a two-domain protein that restricts HIV.
Fareeda M. Barzak +10 more
doaj +1 more source
Molecular Detection and Determination of Phylogenetic Position of Watermelon Chlorotic Stunt Virus Khouzestan Isolate Based on Coat Protein Gene [PDF]
Journal of Genetic ResourcesWatermelon chlorotic stunt virus (WmCSV) is a destructive Begomovirus from the family of Geminiviridae with a bipartite genome including similar-sized circular, single-stranded DNA (DNA-A and DNA-B) which has recently developed dangerously in many ...
Samira Pakbaz +3 more
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Forces in Mechanics, 2021 Single strand DNA-wrapped Single-walled carbon nanotubes (ssDNA-SWCNTs) have critical biomedical applications such as drug delivery, bio-imaging and bio-sensing; therefore, the mechanical interaction between ssDNA-SWCNTs and lipid membranes is an ...
Daisuke Miyashiro +3 more
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Methods and Protocols, 2022 The high failure rate of the in vitro aptamer selection process by SELEX (Systematic Evolution of Ligands by EXponential enrichment) limits the production of these innovative oligonucleotides and, consequently, limits their potential applications.
Lisa Lucie Le Dortz +7 more
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DSS1 and ssDNA regulate oligomerization of BRCA2 [PDF]
Nucleic Acids Research, 2020 Abstract The tumor suppressor BRCA2 plays a key role in initiating homologous recombination by facilitating RAD51 filament formation on single-stranded DNA. The small acidic protein DSS1 is a crucial partner to BRCA2 in this process. In vitro and in cells (1,2), BRCA2 associates into oligomeric complexes besides also existing as monomers.
Hang Phuong Le +6 more
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Mechanochemical regulations of RPA's binding to ssDNA [PDF]
Scientific Reports, 2015 AbstractReplication protein A (RPA) is a ubiquitous eukaryotic single-stranded DNA (ssDNA) binding protein that serves to protect ssDNA from degradation and annealing and as a template for recruitment of many downstream factors in virtually all DNA transactions in cell.
Chen, Jin +4 more
openaire +3 more sources