Results 41 to 50 of about 53,634 (224)
Fluorescent single-stranded DNA-binding protein from Plasmodium falciparum as a biosensor for single-stranded DNA. [PDF]
PLoS ONE, 2018 Single-stranded DNA (ssDNA) is a product of many cellular processes that involve double-stranded DNA, for example during DNA replication and repair, and is formed transiently in many others. Measurement of ssDNA formation is fundamental for understanding
Liisa T Chisty +2 more
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Label-free and sensitive fluorescent detection of sequence-specific single-strand DNA based on S1 nuclease cleavage effects. [PDF]
PLoS ONE, 2014 The ability to detect sequence-specific single-strand DNA (ssDNA) in complex, contaminant-ridden samples, using a fluorescent method directly without a DNA extraction and PCR step could simplify the detection of pathogens in the field and in the clinic ...
Zheng Guan +7 more
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Viruses, 2022 Gene V protein (gVp) of the bacteriophages of the Ff family is a non-specific single-stranded DNA (ssDNA) binding protein. gVp binds to viral DNA during phage replication inside host Escherichia coli cells, thereby blocking further replication and ...
Smadar Kedem +3 more
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Electrochemical and Spectroscopic Study of Samarium Ion Interaction with DNA in Different pHs
International Journal of Electrochemical Science, 2010 In this work, for the first time the electrochemical behavior of the Sm3+ and Sm3+ ion interaction with short single strand DNA (ssDNA) sequence in two pHs was studied. Then the UV-Vis spectroscopic method was used for supporting these evidences.
H. Ilkhani +3 more
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FEBS Open Bio, 2022 The initiation of Okazaki fragment synthesis during cellular DNA replication is a crucial step for lagging strand synthesis, which is carried out by the primase function of DNA polymerase α‐primase (Pol‐prim).
Nichodemus O. Onwubiko +3 more
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Structural Basis of SOSS1 Complex Assembly and Recognition of ssDNA
Cell Reports, 2014 The SOSS1 complex comprising SOSSA, SOSSB1, and SOSSC senses single-stranded DNA (ssDNA) and promotes repair of DNA double-strand breaks (DSBs). But how SOSS1 is assembled and recognizes ssDNA remains elusive. The crystal structure of the N-terminal half
Wendan Ren +6 more
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BMC Genomics, 2023 Background Recent advances in CRISPR technology have enabled us to perform gene knock-in in various species and cell lines. CRISPR-mediated knock-in requires donor DNA which serves as a template for homology-directed repair (HDR).
Akira Mabuchi +10 more
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Mechanism of Dynamic Binding of Replication Protein A to ssDNA [PDF]
Journal of Chemical Information and Modeling, 2020 Abstract Replication protein A (RPA) serves as hub protein inside eukaryotic cells, where it coordinates crucial DNA metabolic processes and activates the DNA-damage response system. A characteristic feature of its action is to associate with ssDNA intermediates before handing over them to downstream proteins.
Anupam Mondal, Arnab Bhattacherjee
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ssDNA sequencing by rectification
, 2018 26 pages, 15 ...
Djurišić, Ivana +5 more
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Biostable ssDNA Aptamers Specific for Hodgkin Lymphoma [PDF]
Sensors, 2013 As a “chemical antibody”, oligonucleotide aptamers can specifically bind to their target molecules. However, clinical potential of aptamers in disease diagnosis is not yet fully explored. Using a tumor cell-based selection protocol, we developed single-stranded DNA aptamers for Hodgkin lymphoma (HL) tumor cells.
Parag Parekh +6 more
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