Results 21 to 30 of about 53,634 (224)

Synthesis of Adenine-based Fluorescent and Naked-eye Chemosensors: Specific DNA Probes for The Detection of Bacterial Pathogens

open access: yesActa Chimica Slovenica, 2021
A rapid and confident tool to identify and diagnose bacterial pathogens with more accuracy using DNA as fingerprints is necessary. Herein, we report a smart chemosensor having a terminal adenine sticking to the thymine of single-stranded DNA (ssDNA ...
Burak Şener   +3 more
doaj   +1 more source

Carbon Nanostructure-Based DNA Sensor Used for Quickly Detecting Breast Cancer-Associated Genes

open access: yesNanoscale Research Letters, 2022
The early diagnosis of breast cancer highly relies on the detection of mutant DNA at low concentrations. Förster resonance energy transfer (FRET) quenching may offer a solution to quickly detect a small amount of single-strand DNA (ssDNA) through the ...
Yingqi Zhang   +4 more
doaj   +1 more source

Concentration-dependent exchange of replication protein A on single-stranded DNA revealed by single-molecule imaging. [PDF]

open access: yesPLoS ONE, 2014
Replication protein A (RPA) is a ubiquitous eukaryotic single-stranded DNA (ssDNA) binding protein necessary for all aspects of DNA metabolism involving an ssDNA intermediate, including DNA replication, repair, recombination, DNA damage response and ...
Bryan Gibb   +6 more
doaj   +1 more source

Small-Angle X-ray Scattering (SAXS) Measurements of APOBEC3G Provide Structural Basis for Binding of Single-Stranded DNA and Processivity

open access: yesViruses, 2022
APOBEC3 enzymes are polynucleotide deaminases, converting cytosine to uracil on single-stranded DNA (ssDNA) and RNA as part of the innate immune response against viruses and retrotransposons. APOBEC3G is a two-domain protein that restricts HIV.
Fareeda M. Barzak   +10 more
doaj   +1 more source

Molecular Detection and Determination of Phylogenetic Position of Watermelon Chlorotic Stunt Virus Khouzestan Isolate Based on Coat Protein Gene [PDF]

open access: yesJournal of Genetic Resources
Watermelon chlorotic stunt virus (WmCSV) is a destructive Begomovirus from the family of Geminiviridae with a bipartite genome including similar-sized circular, single-stranded DNA (DNA-A and DNA-B) which has recently developed dangerously in many ...
Samira Pakbaz   +3 more
doaj   +1 more source

DSS1 and ssDNA regulate oligomerization of BRCA2 [PDF]

open access: yesNucleic Acids Research, 2020
Abstract The tumor suppressor BRCA2 plays a key role in initiating homologous recombination by facilitating RAD51 filament formation on single-stranded DNA. The small acidic protein DSS1 is a crucial partner to BRCA2 in this process. In vitro and in cells (1,2), BRCA2 associates into oligomeric complexes besides also existing as monomers.
Hang Phuong Le   +6 more
openaire   +4 more sources

A real-time fluorescent gp32 probe-based assay for monitoring single-stranded DNA-dependent DNA processing enzymes

open access: yesBiochemistry and Biophysics Reports, 2023
Single-stranded DNA (ssDNA) generated during DNA replication, recombination and damage repair reactions is an important intermediate and ssDNA-binding proteins that binds these intermediates coordinate various DNA metabolic processes. Mechanistic details
Senthil K. Perumal
doaj   +1 more source

Analysis of vibration behavior in single strand DNA-wrapped single-walled carbon nanotubes adhered to lipid membranes

open access: yesForces in Mechanics, 2021
Single strand DNA-wrapped Single-walled carbon nanotubes (ssDNA-SWCNTs) have critical biomedical applications such as drug delivery, bio-imaging and bio-sensing; therefore, the mechanical interaction between ssDNA-SWCNTs and lipid membranes is an ...
Daisuke Miyashiro   +3 more
doaj   +1 more source

Selection and identification of an ssDNA aptamer to NB4 cell [PDF]

open access: yesJournal of Clinical Laboratory Analysis, 2021
AbstractThis study was to find the aptamers with high affinity and specificity binding to acute promyelocytic leukemia (APL) NB4 cell line.These aptamers targeted NB4 cells were selected from a random single‐stranded DNA (ssDNA) library of systematic evolution of ligands by exponential enrichment (CELL‐SELEX). The binding rate of FITC‐ssDNA library and
Xian‐hui Zhang, Wei Wang, Xin Chen
openaire   +2 more sources

Gas Biosensor Arrays Based on Single-Stranded DNA-Functionalized Single-Walled Carbon Nanotubes for the Detection of Volatile Organic Compound Biomarkers Released by Huanglongbing Disease-Infected Citrus Trees

open access: yesSensors, 2019
Volatile organic compounds (VOCs) released by plants are closely associated with plant metabolism and can serve as biomarkers for disease diagnosis. Huanglongbing (HLB), also known as citrus greening or yellow shoot disease, is a lethal threat to the ...
Hui Wang   +6 more
doaj   +1 more source

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